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Volume 98(9);  April 24, 2001
Commentaries
Acclimation of photosynthetic microorganisms to changing ambient CO2 concentration
Aaron Kaplan, Yael Helman, Dan Tchernov, and Leonora Reinhold
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4817–4818. doi: 10.1073/pnas.101119898.
PMCID: PMC33116
How activated receptors couple to G proteins
Heidi E. Hamm
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4819–4821. doi: 10.1073/pnas.011099798.
PMCID: PMC33117
Sea urchin recovery from mass mortality: New hope for Caribbean coral reefs?
Nancy Knowlton
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4822–4824. doi: 10.1073/pnas.091107198.
PMCID: PMC33118
mRNA display: Diversity matters during in vitro selection
Larry Gold
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4825–4826. doi: 10.1073/pnas.091101698.
PMCID: PMC33119
The future of electronics manufacturing is revealed in the fine print
Ralph G. Nuzzo
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4827–4829. doi: 10.1073/pnas.101134798.
PMCID: PMC33120
From molecular genetics to archaeogenetics
Colin Renfrew
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4830–4832. doi: 10.1073/pnas.091084198.
PMCID: PMC33121
Animals know more than we used to think
Donald R. Griffin
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4833–4834. doi: 10.1073/pnas.091088198.
PMCID: PMC33122
Physical Sciences
Applied Physical Sciences
From the Cover:
Paper-like electronic displays: Large-area rubber-stamped plastic sheets of electronics and microencapsulated electrophoretic inks
John A. Rogers, Zhenan Bao, Kirk Baldwin, Ananth Dodabalapur, Brian Crone, V. R. Raju, Valerie Kuck, Howard Katz, Karl Amundson, Jay Ewing, and Paul Drzaic
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4835–4840. doi: 10.1073/pnas.091588098.
PMCID: PMC33123
Chemistry
Even-odd alternation in mass spectrum of thymine and uracil clusters: Evidence of intracluster photodimerization
Nam Joon Kim, Hyuk Kang, Gawoon Jeong, Yung Sam Kim, Kang Taek Lee, and Seong Keun Kim
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4841–4843. Published online 2001 April 10. doi: 10.1073/pnas.091094998.
PMCID: PMC33124
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
Martin Read, R. John Harrison, Barbara Romagnoli, Farial A. Tanious, Sharon H. Gowan, Anthony P. Reszka, W. David Wilson, Lloyd R. Kelland, and Stephen Neidle
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4844–4849. Published online 2001 April 17. doi: 10.1073/pnas.081560598.
PMCID: PMC33125
Geophysics
On strategies for reducing greenhouse gas emissions
Bert Bolin and Haroon S. Kheshgi
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4850–4854. Published online 2001 April 10. doi: 10.1073/pnas.081078998.
PMCID: PMC33126
Physics
Pitch perception: A dynamical-systems perspective
Julyan H. E. Cartwright, Diego L. González, and Oreste Piro
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4855–4859. doi: 10.1073/pnas.081070998.
PMCID: PMC33127
Statistics
The asymptotic distribution of canonical correlations and vectors in higher-order cointegrated models
T. W. Anderson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4860–4865. doi: 10.1073/pnas.071060498.
PMCID: PMC33128
Significance analysis of microarrays applied to the ionizing radiation response
Virginia Goss Tusher, Robert Tibshirani, and Gilbert Chu
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5116–5121. Published online 2001 April 17. doi: 10.1073/pnas.091062498.
PMCID: PMC33173
Biological Sciences
Anthropology
Early Pleistocene 40Ar/39Ar ages for Bapang Formation hominins, Central Jawa, Indonesia
Roy Larick, Russell L. Ciochon, Yahdi Zaim, Sudijono, Suminto, Yan Rizal, Fachroel Aziz, Mark Reagan, and Matthew Heizler
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4866–4871. Published online 2001 April 17. doi: 10.1073/pnas.081077298.
PMCID: PMC33129
Biochemistry
Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants
John Hwa, Judith Klein-Seetharaman, and H. Gobind Khorana
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4872–4876. doi: 10.1073/pnas.061632798.
PMCID: PMC33130
From the Cover:
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: Use of a photoactivatable reagent
Kewen Cai, Yoshiki Itoh, and H. Gobind Khorana
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4877–4882. doi: 10.1073/pnas.051632898.
PMCID: PMC33131
Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: Use of a chemically preactivated reagent
Yoshiki Itoh, Kewen Cai, and H. Gobind Khorana
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4883–4887. doi: 10.1073/pnas.051632998.
PMCID: PMC33132
Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin
Michèle C. Loewen, Judith Klein-Seetharaman, Elena V. Getmanova, Philip J. Reeves, Harald Schwalbe, and H. Gobind Khorana
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4888–4892. doi: 10.1073/pnas.051633098.
PMCID: PMC33133
Dynamics of Fos-Jun-NFAT1 complexes
Vladimir R. Ramirez-Carrozzi and Tom K. Kerppola
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4893–4898. doi: 10.1073/pnas.091095998.
PMCID: PMC33134
RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
Poul Nissen, Joseph A. Ippolito, Nenad Ban, Peter B. Moore, and Thomas A. Steitz
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4899–4903. Published online 2001 April 10. doi: 10.1073/pnas.081082398.
PMCID: PMC33135
Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
John S. Sack, Kevin F. Kish, Chihuei Wang, Ricardo M. Attar, Susan E. Kiefer, Yongmi An, Ginger Y. Wu, Julie E. Scheffler, Mark E. Salvati, Stanley R. Krystek, Jr., Roberto Weinmann, and Howard M. Einspahr
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4904–4909. doi: 10.1073/pnas.081565498.
PMCID: PMC33136
Systemic spread of an RNA insect virus in plants expressing plant viral movement protein genes
Ranjit Dasgupta, Bradley H. Garcia, II, and Robert M. Goodman
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4910–4915. Published online 2001 April 10. doi: 10.1073/pnas.081288198.
PMCID: PMC33137
Vitamin B12 and hepatitis C: Molecular biology and human pathology
William B. Lott, Seyedtaghi S. Takyar, Joseph Tuppen, Darrell H. G. Crawford, Michael Harrison, Theo P. Sloots, and Eric J. Gowans
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4916–4921. Published online 2001 April 10. doi: 10.1073/pnas.081072798.
PMCID: PMC33138
Unnatural base pairs for specific transcription
Takashi Ohtsuki, Michiko Kimoto, Masahide Ishikawa, Tsuneo Mitsui, Ichiro Hirao, and Shigeyuki Yokoyama
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4922–4925. doi: 10.1073/pnas.091532698.
PMCID: PMC33139
Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts)
A. A. Waheed, Yukiko Shimada, Harry F. G. Heijnen, Megumi Nakamura, Mitsushi Inomata, Masami Hayashi, Shintaro Iwashita, Jan W. Slot, and Yoshiko Ohno-Iwashita
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4926–4931. Published online 2001 April 17. doi: 10.1073/pnas.091090798.
PMCID: PMC33140
Desorption/ionization on silicon (DIOS): A diverse mass spectrometry platform for protein characterization
John J. Thomas, Zhouxin Shen, John E. Crowell, M. G. Finn, and Gary Siuzdak
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4932–4937. Published online 2001 April 10. doi: 10.1073/pnas.081069298.
PMCID: PMC33141
Similarities between the DNA replication initiators of Gram-negative bacteria plasmids (RepA) and eukaryotes (Orc4p)/archaea (Cdc6p)
Rafael Giraldo and Ramón Díaz-Orejas
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4938–4943. Published online 2001 April 10. doi: 10.1073/pnas.081079298.
PMCID: PMC33142
Dynamic properties of the Ras switch I region and its importance for binding to effectors
Michael Spoerner, Christian Herrmann, Ingrid R. Vetter, Hans Robert Kalbitzer, and Alfred Wittinghofer
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4944–4949. doi: 10.1073/pnas.081441398.
PMCID: PMC33143
Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells
Brian M. Davis, Lance P. Encell, Steven P. Zielske, Fred C. Christians, Lili Liu, Sarah E. Friebert, Lawrence A. Loeb, and Stanton L. Gerson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4950–4954. Published online 2001 April 10. doi: 10.1073/pnas.091601198.
PMCID: PMC33144
Conversion of a maltose receptor into a zinc biosensor by computational design
Jonathan S. Marvin and Homme W. Hellinga
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4955–4960. doi: 10.1073/pnas.091083898.
PMCID: PMC33145
Controlling small guanine–nucleotide-exchange factor function through cytoplasmic RNA intramers
Günter Mayer, Michael Blind, Wolfgang Nagel, Thomas Böhm, Thomas Knorr, Catherine L. Jackson, Waldemar Kolanus, and Michael Famulok
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4961–4965. doi: 10.1073/pnas.091100698.
PMCID: PMC33146
The preferred stoichiometry of c subunits in the rotary motor sector of Escherichia coli ATP synthase is 10
Weiping Jiang, Joe Hermolin, and Robert H. Fillingame
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4966–4971. doi: 10.1073/pnas.081424898.
PMCID: PMC33147
Factors regulating template switch in vitro by viral RNA-dependent RNA polymerases: Implications for RNA–RNA recombination
M.-J. Kim and C. Kao
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4972–4977. Published online 2001 April 17. doi: 10.1073/pnas.081077198.
PMCID: PMC33148
DNA polymerase [var epsilon] is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts
Shou Waga, Taro Masuda, Haruhiko Takisawa, and Akio Sugino
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4978–4983. Published online 2001 April 10. doi: 10.1073/pnas.081088798.
PMCID: PMC33149
Efficient pyrophosphorolysis by a hepatitis B virus polymerase may be a primer-unblocking mechanism
Sinisa Urban, Severin Urban, Karl P. Fischer, and D. Lorne Tyrrell
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4984–4989. doi: 10.1073/pnas.091324398.
PMCID: PMC33150
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
Frédérique Magdinier and Alan P. Wolffe
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4990–4995. Published online 2001 April 17. doi: 10.1073/pnas.101617298.
PMCID: PMC33151
Hydrophobic moments of protein structures: Spatially profiling the distribution
B. David Silverman
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4996–5001. Published online 2001 April 17. doi: 10.1073/pnas.081086198.
PMCID: PMC33152
Biophysics
Electron tunneling in protein crystals
F. Akif Tezcan, Brian R. Crane, Jay R. Winkler, and Harry B. Gray
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5002–5006. Published online 2001 April 10. doi: 10.1073/pnas.081072898.
PMCID: PMC33153
Visualization of unwinding activity of duplex RNA by DbpA, a DEAD box helicase, at single-molecule resolution by atomic force microscopy
Arnon Henn, Ohad Medalia, Shu-Ping Shi, Michal Steinberg, Francois Franceschi, and Irit Sagi
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5007–5012. Published online 2001 April 10. doi: 10.1073/pnas.071372498.
PMCID: PMC33154
On the role of the K-proton transfer pathway in cytochrome c oxidase
Magnus Brändén, Håkan Sigurdson, Andreas Namslauer, Robert B. Gennis, Pia Ädelroth, and Peter Brzezinski
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5013–5018. Published online 2001 April 10. doi: 10.1073/pnas.081088398.
PMCID: PMC33155
Balanced branching in transcription termination
K. J. Harrington, R. B. Laughlin, and S. Liang
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5019–5024. Published online 2001 April 17. doi: 10.1073/pnas.240431598.
PMCID: PMC33156
Cell Biology
Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation
Athena W. Lin and Scott W. Lowe
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5025–5030. Published online 2001 April 17. doi: 10.1073/pnas.091100298.
PMCID: PMC33157
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene
Bing Zhu, Don Benjamin, Yong Zheng, Herbert Angliker, Stéphane Thiry, Michel Siegmann, and Jean-Pierre Jost
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5031–5036. Published online 2001 April 10. doi: 10.1073/pnas.091097298.
PMCID: PMC33158
Muscle-regulated expression and determinants for neuromuscular junctional localization of the mouse RIα regulatory subunit of cAMP- dependent protein kinase
Sébastien Barradeau, Tereza Imaizumi-Scherrer, Mary C. Weiss, and Daniela M. Faust
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5037–5042. Published online 2001 April 10. doi: 10.1073/pnas.081393598.
PMCID: PMC33159
Skp2 is oncogenic and overexpressed in human cancers
Matthias Gstaiger, Richard Jordan, Megan Lim, Charles Catzavelos, Jürgen Mestan, Joyce Slingerland, and Wilhelm Krek
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5043–5048. Published online 2001 April 17. doi: 10.1073/pnas.081474898.
PMCID: PMC33160
Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation
Damiano Conte, Peter Liston, James W. Wong, Kathryn E. Wright, and Robert G. Korneluk
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5049–5054. Published online 2001 April 17. doi: 10.1073/pnas.081547998.
PMCID: PMC33161
Developmental Biology
Activation of a protease cascade involved in patterning the Drosophila embryo
Ellen K. LeMosy, Yue-Qing Tan, and Carl Hashimoto
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5055–5060. Published online 2001 April 10. doi: 10.1073/pnas.081026598.
PMCID: PMC33162
The Caenorhabditis elegans maternal-effect sterile proteins, MES-2, MES-3, and MES-6, are associated in a complex in embryos
Lei Xu, Youyi Fong, and Susan Strome
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5061–5066. doi: 10.1073/pnas.081016198.
PMCID: PMC33163
Ecology
From the Cover:
Recovery of Diadema antillarum reduces macroalgal cover and increases abundance of juvenile corals on a Caribbean reef
Peter J. Edmunds and Robert C. Carpenter
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5067–5071. Published online 2001 March 27. doi: 10.1073/pnas.071524598.
PMCID: PMC33164
Estimating risks in declining populations with poor data
Elizabeth E. Holmes
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5072–5077. Published online 2001 April 17. doi: 10.1073/pnas.081055898.
PMCID: PMC33165
Evolution
From the Cover:
Genetic evidence for different male and female roles during cultural transitions in the British Isles
James F. Wilson, Deborah A. Weiss, Martin Richards, Mark G. Thomas, Neil Bradman, and David B. Goldstein
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5078–5083. Published online 2001 April 3. doi: 10.1073/pnas.071036898.
PMCID: PMC33166
Dynamics of mobile element activity in chalcone synthase loci in the common morning glory (Ipomoea purpurea)
Mary L. Durbin, Amy L. Denton, and Michael T. Clegg
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5084–5089. Published online 2001 April 17. doi: 10.1073/pnas.091095498.
PMCID: PMC33167
Genetic documentation of filial cannibalism in nature
J. Andrew DeWoody, Dean E. Fletcher, S. David Wilkins, and John C. Avise
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5090–5092. Published online 2001 April 17. doi: 10.1073/pnas.091102598.
PMCID: PMC33168
Genetics
Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys
Tsuyoshi Kayo, David B. Allison, Richard Weindruch, and Tomas A. Prolla
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5093–5098. Published online 2001 April 17. doi: 10.1073/pnas.081061898.
PMCID: PMC33169
Complex mtDNA constitutes an approximate 620-kb insertion on Arabidopsis thaliana chromosome 2: Implication of potential sequencing errors caused by large-unit repeats
Robert M. Stupar, Jason W. Lilly, Christopher D. Town, Zhukuan Cheng, Samir Kaul, C. Robin Buell, and Jiming Jiang
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5099–5103. Published online 2001 April 17. doi: 10.1073/pnas.091110398.
PMCID: PMC33170
Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes
Philippe Mulsant, Frédéric Lecerf, Stéphane Fabre, Laurent Schibler, Philippe Monget, Isabelle Lanneluc, Claudine Pisselet, Juliette Riquet, Danielle Monniaux, Isabelle Callebaut, Edmond Cribiu, Jacques Thimonier, Jacques Teyssier, Loys Bodin, Yves Cognié, Nour Chitour, and Jean-Michel Elsen
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5104–5109. doi: 10.1073/pnas.091577598.
PMCID: PMC33171
Gene discovery and gene function assignment in filamentous fungi
Lisbeth Hamer, Kiichi Adachi, Maria V. Montenegro-Chamorro, Matthew M. Tanzer, Sanjoy K. Mahanty, Clive Lo, Rex W. Tarpey, Amy R. Skalchunes, Ryan W. Heiniger, Sheryl A. Frank, Blaise A. Darveaux, David J. Lampe, Ted M. Slater, Lakshman Ramamurthy, Todd M. DeZwaan, Grant H. Nelson, Jeffrey R. Shuster, Jeffrey Woessner, and John E. Hamer
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5110–5115. Published online 2001 April 10. doi: 10.1073/pnas.091094198.
PMCID: PMC33172
Significance analysis of microarrays applied to the ionizing radiation response
Virginia Goss Tusher, Robert Tibshirani, and Gilbert Chu
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5116–5121. Published online 2001 April 17. doi: 10.1073/pnas.091062498.
PMCID: PMC33173
The 3′→5′ exonuclease of DNA polymerase δ can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability
Yong Hwan Jin, Robyn Obert, Peter M. J. Burgers, Thomas A. Kunkel, Michael A. Resnick, and Dmitry A. Gordenin
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5122–5127. Published online 2001 April 17. doi: 10.1073/pnas.091095198.
PMCID: PMC33174
An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY
Hiroyuki Mori and Koreaki Ito
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5128–5133. Published online 2001 April 17. doi: 10.1073/pnas.081617398.
PMCID: PMC33175
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
Heinz Ruffner, Claudio A. P. Joazeiro, Dan Hemmati, Tony Hunter, and Inder M. Verma
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5134–5139. doi: 10.1073/pnas.081068398.
PMCID: PMC33176
Immunology
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity
Pedro O. Flores-Villanueva, Edmond J. Yunis, Julio C. Delgado, Eric Vittinghoff, Susan Buchbinder, Jessica Y. Leung, Adele M. Uglialoro, Olga P. Clavijo, Eric S. Rosenberg, Spyros A. Kalams, James D. Braun, Stephen L. Boswell, Bruce D. Walker, and Anne E. Goldfeld
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5140–5145. Published online 2001 April 17. doi: 10.1073/pnas.071548198.
PMCID: PMC33177
Comparative assessment of virulence of recombinant vaccinia viruses expressing IL-2 and IL-15 in immunodeficient mice
Liyanage P. Perera, Carolyn K. Goldman, and Thomas A. Waldmann
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5146–5151. Published online 2001 April 10. doi: 10.1073/pnas.081080298.
PMCID: PMC33178
IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression
Rainer Spanbroek, Markus Hildner, André Köhler, Angelika Müller, Felix Zintl, Hartmut Kühn, Olof Rådmark, Bengt Samuelsson, and Andreas J. R. Habenicht
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5152–5157. doi: 10.1073/pnas.091076998.
PMCID: PMC33179
Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: Sensitivity of human thymocytes
Anna Katharina Simon, Owen Williams, Juthathip Mongkolsapaya, Boquan Jin, Xiao Ning Xu, Henning Walczak, and Gavin R. Screaton
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5158–5163. Published online 2001 April 17. doi: 10.1073/pnas.091100398.
PMCID: PMC33180
Commitment to natural killer cells requires the helix–loop–helix inhibitor Id2
Tomokatsu Ikawa, Shinji Fujimoto, Hiroshi Kawamoto, Yoshimoto Katsura, and Yoshifumi Yokota
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5164–5169. Published online 2001 April 10. doi: 10.1073/pnas.091537598.
PMCID: PMC33181
Medical Sciences
Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β2-microglobulin-deficient mice
Thomas J. Sproule, Elizabeth C. Jazwinska, Robert S. Britton, Bruce R. Bacon, Robert E. Fleming, William S. Sly, and Derry C. Roopenian
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5170–5174. Published online 2001 April 17. doi: 10.1073/pnas.091088998.
PMCID: PMC33182
Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma
Atsushi Nakanishi, Shigeru Morita, Hiroki Iwashita, Yoji Sagiya, Yasuko Ashida, Hideo Shirafuji, Yukio Fujisawa, Osamu Nishimura, and Masahiko Fujino
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5175–5180. Published online 2001 April 10. doi: 10.1073/pnas.081510898.
PMCID: PMC33183
Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models
Moshe Mittelman, Drorit Neumann, Alpha Peled, Pazit Kanter, and Nechama Haran-Ghera
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5181–5186. Published online 2001 April 17. doi: 10.1073/pnas.081275298.
PMCID: PMC33184
Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance
Janice M. Zabolotny, Young-Bum Kim, Odile D. Peroni, Jason K. Kim, Michael A. Pani, Olivier Boss, Lori D. Klaman, Shubhangi Kamatkar, Gerald I. Shulman, Barbara B. Kahn, and Benjamin G. Neel
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5187–5192. Published online 2001 April 17. doi: 10.1073/pnas.071050398.
PMCID: PMC33185
In vivo restoration of laminin 5 β3 expression and function in junctional epidermolysis bullosa
Paul B. Robbins, Qun Lin, Julia B. Goodnough, Hongsheng Tian, Xinjian Chen, and Paul A. Khavari
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5193–5198. Published online 2001 April 10. doi: 10.1073/pnas.091484998.
PMCID: PMC33186
Global survey of genetic variation in CCR5, RANTES, and MIP-1α: Impact on the epidemiology of the HIV-1 pandemic
Enrique Gonzalez, Rahul Dhanda, Mike Bamshad, Srinivas Mummidi, Reni Geevarghese, Gabriel Catano, Stephanie A. Anderson, Elizabeth A. Walter, Kevin T. Stephan, Michael F. Hammer, Andrea Mangano, Luisa Sen, Robert A. Clark, Seema S. Ahuja, Matthew J. Dolan, and Sunil K. Ahuja
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5199–5204. doi: 10.1073/pnas.091056898.
PMCID: PMC33187
In vivo detection of gene expression in liver by 31P nuclear magnetic resonance spectroscopy employing creatine kinase as a marker gene
Alberto Auricchio, Rong Zhou, James M. Wilson, and Jerry D. Glickson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5205–5210. Published online 2001 April 10. doi: 10.1073/pnas.081508598.
PMCID: PMC33188
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension
Vijaykumar R. Holla, Fadi Adas, John D. Imig, Xueying Zhao, Edward Price, Jr., Nancy Olsen, William J. Kovacs, Mark A. Magnuson, Diane S. Keeney, Matthew D. Breyer, John R. Falck, Michael R. Waterman, and Jorge H. Capdevila
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5211–5216. doi: 10.1073/pnas.081627898.
PMCID: PMC33189
The optimal measure of allelic association
N. E. Morton, W. Zhang, P. Taillon-Miller, S. Ennis, P.-Y. Kwok, and A. Collins
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5217–5221. Published online 2001 April 17. doi: 10.1073/pnas.091062198.
PMCID: PMC33190
Microbiology
Characterization of a Plasmodium falciparum erythrocyte-binding protein paralogous to EBA-175
D. C. Ghislaine Mayer, Osamu Kaneko, Diana E. Hudson-Taylor, Marion E. Reid, and Louis H. Miller
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5222–5227. Published online 2001 April 17. doi: 10.1073/pnas.081075398.
PMCID: PMC33191
Anti-mosquito midgut antibodies block development of Plasmodium falciparum and Plasmodium vivax in multiple species of Anopheles mosquitoes and reduce vector fecundity and survivorship
Altaf A. Lal, Pamela S. Patterson, John B. Sacci, Jefferson A. Vaughan, Chris Paul, William E. Collins, Robert A. Wirtz, and Abdu F. Azad
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5228–5233. Published online 2001 April 17. doi: 10.1073/pnas.091447398.
PMCID: PMC33192
Fit genotypes and escape variants of subgroup III Neisseria meningitidis during three pandemics of epidemic meningitis
Peixuan Zhu, Arie van der Ende, Daniel Falush, Norbert Brieske, Giovanna Morelli, Bodo Linz, Tanja Popovic, Ilse G. A. Schuurman, Richard A. Adegbola, Kerstin Zurth, Sébastien Gagneux, Alexander E. Platonov, Jean-Yves Riou, Dominique A. Caugant, Pierre Nicolas, and Mark Achtman
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5234–5239. Published online 2001 April 3. doi: 10.1073/pnas.061386098.
PMCID: PMC33193
Predicted highly expressed and putative alien genes of Deinococcus radiodurans and implications for resistance to ionizing radiation damage
Samuel Karlin and Jan Mrázek
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5240–5245. Published online 2001 April 10. doi: 10.1073/pnas.081077598.
PMCID: PMC33194
RNA is a structural element in retrovirus particles
Delphine Muriaux, Jane Mirro, Demetria Harvin, and Alan Rein
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5246–5251. doi: 10.1073/pnas.091000398.
PMCID: PMC33195
Neurobiology
Pitch perception: A dynamical-systems perspective
Julyan H. E. Cartwright, Diego L. González, and Oreste Piro
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4855–4859. doi: 10.1073/pnas.081070998.
PMCID: PMC33127
A wholly empirical explanation of perceived motion
Zhiyong Yang, Amita Shimpi, and Dale Purves
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5252–5257. doi: 10.1073/pnas.091095298.
PMCID: PMC33196
Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A
Ridwan Lin, Kelly Karpa, Nadine Kabbani, Patricia Goldman-Rakic, and Robert Levenson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5258–5263. doi: 10.1073/pnas.011538198.
PMCID: PMC33197
γ-Aminobutyric acid type A receptors modulate cAMP-mediated long-term potentiation and long-term depression at monosynaptic CA3–CA1 synapses
Tzu-ping Yu, Sheri McKinney, Henry A. Lester, and Norman Davidson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5264–5269. Published online 2001 April 10. doi: 10.1073/pnas.091093998.
PMCID: PMC33198
Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei
Mariela Zirlinger, Gabriel Kreiman, and David J. Anderson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5270–5275. doi: 10.1073/pnas.091094698.
PMCID: PMC33199
Characterization of a high-voltage-activated IA current with a role in spike timing and locomotor pattern generation
Dietmar Hess and Abdeljabbar El Manira
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5276–5281. Published online 2001 April 17. doi: 10.1073/pnas.091096198.
PMCID: PMC33200
From the Cover:
Tracking memory's trace
Gabriel Horn, Alister U. Nicol, and Malcolm W. Brown
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5282–5287. Published online 2001 April 10. doi: 10.1073/pnas.091094798.
PMCID: PMC33201
Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors
Baljit S. Khakh, W. Bryan Smith, Chi-Sung Chiu, Donghong Ju, Norman Davidson, and Henry A. Lester
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5288–5293. Published online 2001 April 10. doi: 10.1073/pnas.081089198.
PMCID: PMC33202
A new strategy to decrease N-methyl-d-aspartate (NMDA) receptor coactivation: Inhibition of d-serine synthesis by converting serine racemase into an eliminase
Rogério Panizzutti, Joari De Miranda, Cátia S. Ribeiro, Simone Engelender, and Herman Wolosker
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5294–5299. Published online 2001 April 17. doi: 10.1073/pnas.091002298.
PMCID: PMC33203
Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
Ichiro Sora, F. Scott Hall, Anne M. Andrews, Masanari Itokawa, Xiao-Fei Li, Hong-Bing Wei, Christine Wichems, Klaus-Peter Lesch, Dennis L. Murphy, and George R. Uhl
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5300–5305. doi: 10.1073/pnas.091039298.
PMCID: PMC33204
Pharmacology
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
William R. Oliver, Jr., Jennifer L. Shenk, Mike R. Snaith, Caroline S. Russell, Kelli D. Plunket, Noni L. Bodkin, Michael C. Lewis, Deborah A. Winegar, Marcos L. Sznaidman, Millard H. Lambert, H. Eric Xu, Daniel D. Sternbach, Steven A. Kliewer, Barbara C. Hansen, and Timothy M. Willson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5306–5311. Published online 2001 April 17. doi: 10.1073/pnas.091021198.
PMCID: PMC33205
The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density
James P. Snyder, James H. Nettles, Ben Cornett, Kenneth H. Downing, and Eva Nogales
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5312–5316. Published online 2001 April 17. doi: 10.1073/pnas.051309398.
PMCID: PMC33206
Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells
Gerson M. Rocha, Luis F. Michea, Eugenia M. Peters, Martha Kirby, Yuhui Xu, Douglas R. Ferguson, and Maurice B. Burg
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5317–5322. doi: 10.1073/pnas.091057698.
PMCID: PMC33207
Physiology
Functional disorders of the sympathetic nervous system in mice lacking the α1B subunit (Cav 2.2) of N-type calcium channels
Mitsuhiro Ino, Takashi Yoshinaga, Minoru Wakamori, Norimasa Miyamoto, Eiki Takahashi, Jiro Sonoda, Takaki Kagaya, Tohru Oki, Takeshi Nagasu, Yukio Nishizawa, Isao Tanaka, Keiji Imoto, Shinichi Aizawa, Sheryl Koch, Arnold Schwartz, Tetsuhiro Niidome, Kohei Sawada, and Yasuo Mori
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5323–5328. Published online 2001 April 10. doi: 10.1073/pnas.081089398.
PMCID: PMC33208
Defective regulatory volume decrease in human cystic fibrosis tracheal cells because of altered regulation of intermediate conductance Ca2+-dependent potassium channels
Esther Vázquez, Muriel Nobles, and Miguel A. Valverde
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5329–5334. Published online 2001 April 17. doi: 10.1073/pnas.091096498.
PMCID: PMC33209
Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1
Uta C. Hoppe, Eduardo Marbán, and David C. Johns
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5335–5340. doi: 10.1073/pnas.091239098.
PMCID: PMC33210
Plant Biology
The Cia5 gene controls formation of the carbon concentrating mechanism in Chlamydomonas reinhardtii
Youbin Xiang, Jun Zhang, and Donald P. Weeks
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5341–5346. Published online 2001 April 17. doi: 10.1073/pnas.101534498.
PMCID: PMC33211
Ccm1, a regulatory gene controlling the induction of a carbon-concentrating mechanism in Chlamydomonas reinhardtii by sensing CO2 availability
Hideya Fukuzawa, Kenji Miura, Kimitsune Ishizaki, Ken-ichi Kucho, Tatsuaki Saito, Tsutomu Kohinata, and Kanji Ohyama
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5347–5352. Published online 2001 April 3. doi: 10.1073/pnas.081593498.
PMCID: PMC33212
The ricinosomes of senescing plant tissue bud from the endoplasmic reticulum
Markus Schmid, David J. Simpson, Hakan Sarioglu, Friedrich Lottspeich, and Christine Gietl
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5353–5358. Published online 2001 April 10. doi: 10.1073/pnas.061038298.
PMCID: PMC33213
Psychology
Rhesus monkeys know when they remember
Robert R. Hampton
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5359–5362. Published online 2001 March 27. doi: 10.1073/pnas.071600998.
PMCID: PMC33214
Covert attention accelerates the rate of visual information processing
Marisa Carrasco and Brian McElree
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5363–5367. Published online 2001 April 17. doi: 10.1073/pnas.081074098.
PMCID: PMC33215
Social Sciences
Economic Sciences
The asymptotic distribution of canonical correlations and vectors in higher-order cointegrated models
T. W. Anderson
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 4860–4865. doi: 10.1073/pnas.071060498.
PMCID: PMC33128
Corrections
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5368. doi: 10.1073/pnas.111142398.
PMCID: PMC55948
Corrects: Bradley E. Bernstein, et al. Genomewide studies of histone deacetylase function in yeast. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13708–13713.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5368. doi: 10.1073/pnas.111142498.
PMCID: PMC55949
Corrects: Giampaolo Zuccheri, et al. Mapping the intrinsic curvature and flexibility along the DNA chain. Proc Natl Acad Sci U S A. 2001 March 13; 98(6): 3074–3079.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5368. doi: 10.1073/pnas.111142598.
PMCID: PMC55950
Corrects: Santos Alonso, et al. A highly variable segment of human subterminal 16p reveals a history of population growth for modern humans outside Africa. Proc Natl Acad Sci U S A. 2001 January 30; 98(3): 864–869.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.111149198.
PMCID: PMC55951
Corrects: Hirofumi Onishi, et al. Functional transitions in myosin: Formation of a critical salt-bridge and transmission of effect to the sensitive tryptophan. Proc Natl Acad Sci U S A. 1998 June 9; 95(12): 6653–6658.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. Published online 2001 April 10. doi: 10.1073/pnas.111142898.
PMCID: PMC55952
Corrects: Shila Jalali, et al. Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc Natl Acad Sci U S A. 2001 January 30; 98(3): 1042–1046.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.101139898.
PMCID: PMC55953
Corrects: Hyoung Doo Shin, et al. Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10. Proc Natl Acad Sci U S A. 2000 December 19; 97(26): 14467–14472.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.111148898.
PMCID: PMC55954
Corrects: Lubor Borsig, et al. Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci U S A. 2001 March 13; 98(6): 3352–3357.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.111153498.
PMCID: PMC55955
Corrects: Kelly A. Brayton, et al. Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens. Proc Natl Acad Sci U S A. 2001 March 27; 98(7): 4130–4135.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.091115198.
PMCID: PMC55956
Corrects: E. Imre Friedmann, et al. Special Feature: Chains of magnetite crystals in the meteorite ALH84001: Evidence of biological origin. Proc Natl Acad Sci U S A. 2001 February 27; 98(5): 2176–2181.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. doi: 10.1073/pnas.091115298.
PMCID: PMC55957
Corrects: Jeremy K. Seamans, et al. Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons. Proc Natl Acad Sci U S A. 2001 January 2; 98(1): 301–306.
Correction
Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5369. Published online 2001 April 10. doi: 10.1073/pnas.101139998.
PMCID: PMC55958
Corrects: Kinji Ohno, et al. Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans. Proc Natl Acad Sci U S A. 2001 February 13; 98(4): 2017–2022.
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