| | This journal provides immediate access to some articles. Commentaries Networking proteins in yeast Tony R. Hazbun and Stanley Fields Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4277–4278. doi: 10.1073/pnas.091096398.PMCID: PMC33318 Circumventing leptin resistance for weight control Satya P. Kalra Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4279–4281. doi: 10.1073/pnas.091101498.PMCID: PMC33319 Who's got pull around here? Cell organization in development and
tissue engineering D. A. Lauffenburger and L. G. Griffith Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4282–4284. doi: 10.1073/pnas.081083698.PMCID: PMC33320 New transformation tricks from a barnyard retrovirus:
Implications for human lung cancer Naomi Rosenberg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4285–4287. doi: 10.1073/pnas.091097698.PMCID: PMC33321 Delivering messages from the 3′ end Gabriele Varani Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4288–4289. doi: 10.1073/pnas.091108098.PMCID: PMC33322 Biological diversity and resource plunder in the geological
record: Casual correlations or causal relationships? Paul G. Falkowski and Yair Rosenthal Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4290–4292. doi: 10.1073/pnas.091096798.PMCID: PMC33323 Retroviruses and the pathogenesis of schizophrenia David A. Lewis Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4293–4294. doi: 10.1073/pnas.081075898.PMCID: PMC33324 Perspective The many ways to cross the plasma membrane David J. Stephens and Rainer Pepperkok Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4295–4298. Published online 2001 March 27. doi: 10.1073/pnas.081065198.PMCID: PMC33325 Physical Sciences Chemistry On the absorbance changes in the photocycle of the photoactive
yellow protein: A quantum-chemical analysis Vicent Molina and Manuela Merchán Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4299–4304. Published online 2001 April 3. doi: 10.1073/pnas.071058098.PMCID: PMC31828 Geology From the Cover: Global biodiversity and the ancient carbon cycle Daniel H. Rothman Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4305–4310. doi: 10.1073/pnas.071047798.PMCID: PMC31829 Mathematics Behavior of several two-dimensional fluid equations in singular
scenarios Diego Cordoba and Charles Fefferman Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4311–4312. Published online 2001 March 27. doi: 10.1073/pnas.061038998.PMCID: PMC31830 A positivity result in the theory of Macdonald polynomials A. M. Garsia and J. Haglund Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4313–4316. Published online 2001 March 27. doi: 10.1073/pnas.071043398.PMCID: PMC31831 Biological Sciences Anthropology A molecular analysis of dietary diversity for three archaic
Native Americans Hendrik N. Poinar, Melanie Kuch, Kristin D. Sobolik, Ian Barnes, Artur B. Stankiewicz, Tomasz Kuder, W. Geofferey Spaulding, Vaughn M. Bryant, Alan Cooper, and Svante Pääbo Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4317–4322. doi: 10.1073/pnas.061014798.PMCID: PMC31832 Applied Biological Sciences Tissue spreading on implantable substrates is a competitive
outcome of cell–cell vs. cell–substratum adhesivity Peter L. Ryan, Ramsey A. Foty, Joachim Kohn, and Malcolm S. Steinberg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4323–4327. Published online 2001 March 27. doi: 10.1073/pnas.071615398.PMCID: PMC31833 Biochemistry Translocation pathway of protein substrates in ClpAP protease Takashi Ishikawa, Fabienne Beuron, Martin Kessel, Sue Wickner, Michael R. Maurizi, and Alasdair C. Steven Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4328–4333. Published online 2001 April 3. doi: 10.1073/pnas.081543698.PMCID: PMC31834 A role for intermolecular disulfide bonds in prion diseases? Ervin Welker, William J. Wedemeyer, and Harold A. Scheraga Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4334–4336. Published online 2001 March 27. doi: 10.1073/pnas.071066598.PMCID: PMC31835 Crystal structure of cis-prenyl chain elongating
enzyme, undecaprenyl diphosphate synthase Masahiro Fujihashi, Yuan-Wei Zhang, Yoshiki Higuchi, Xiao-Yuan Li, Tanetoshi Koyama, and Kunio Miki Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4337–4342. Published online 2001 April 3. doi: 10.1073/pnas.071514398.PMCID: PMC31836 Toward rules for 1:1 polyamide:DNA recognition Adam R. Urbach and Peter B. Dervan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4343–4348. doi: 10.1073/pnas.081070798.PMCID: PMC31837 Protein folding from a highly disordered denatured state: The
folding pathway of chymotrypsin inhibitor 2 at
atomic resolution Steven L. Kazmirski, Kam-Bo Wong, Stefan M. V. Freund, Yee-Joo Tan, Alan R. Fersht, and Valerie Daggett Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4349–4354. Published online 2001 March 27. doi: 10.1073/pnas.071054398.PMCID: PMC31838 The thermodynamic origin of the stability of a thermophilic
ribozyme X.-W. Fang, B. L. Golden, K. Littrell, V. Shelton, P. Thiyagarajan, T. Pan, and T. R. Sosnick Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4355–4360. doi: 10.1073/pnas.071050698.PMCID: PMC31839 Three-dimensional image reconstruction of dephosphorylated smooth
muscle heavy meromyosin reveals asymmetry in the interaction
between myosin heads and placement of subfragment 2 Thomas Wendt, Dianne Taylor, Kathleen M. Trybus, and Kenneth Taylor Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4361–4366. Published online 2001 April 3. doi: 10.1073/pnas.071051098.PMCID: PMC31840 Prediction of protein deamidation rates from primary and
three-dimensional structure Noah E. Robinson and Arthur B. Robinson Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4367–4372. doi: 10.1073/pnas.071066498.PMCID: PMC31841 Chrysanthemyl diphosphate synthase: Isolation of the gene and
characterization of the recombinant non-head-to-tail monoterpene
synthase from Chrysanthemum cinerariaefolium Susan B. Rivera, Bradley D. Swedlund, Gretchen J. King, Russell N. Bell, Charles E. Hussey, Jr., Donna M. Shattuck-Eidens, Wislawa M. Wrobel, Galen D. Peiser, and C. Dale Poulter Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4373–4378. Published online 2001 April 3. doi: 10.1073/pnas.071543598.PMCID: PMC31842 Ligand-independent oligomerization of cell-surface erythropoietin
receptor is mediated by the transmembrane domain Stefan N. Constantinescu, Tzvia Keren, Merav Socolovsky, Hyung-song Nam, Yoav I. Henis, and Harvey F. Lodish Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4379–4384. doi: 10.1073/pnas.081069198.PMCID: PMC31843 Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by
interaction with Tiam1 Yoshiro Otsuki, Masamitsu Tanaka, Shigeto Yoshii, Nobuko Kawazoe, Kazuyasu Nakaya, and Haruhiko Sugimura Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4385–4390. Published online 2001 March 27. doi: 10.1073/pnas.071411598.PMCID: PMC31844 HDA2 and HDA3 are related proteins that interact with and are
essential for the activity of the yeast histone deacetylase HDA1 Jiansheng Wu, Andrew A. Carmen, Ryuji Kobayashi, Noriyuki Suka, and Michael Grunstein Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4391–4396. Published online 2001 April 3. doi: 10.1073/pnas.081560698.PMCID: PMC31845 A ribulose-1,5-bisphosphate carboxylase/oxygenase
(RubisCO)-like protein from Chlorobium tepidum that
is involved with sulfur metabolism and the response to
oxidative stress Thomas E. Hanson and F. Robert Tabita Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4397–4402. Published online 2001 April 3. doi: 10.1073/pnas.081610398.PMCID: PMC31846 Attomole level protein sequencing by Edman degradation coupled
with accelerator mass spectrometry Masahiro Miyashita, Jack M. Presley, Bruce A. Buchholz, Kit S. Lam, Young Moo Lee, John S. Vogel, and Bruce D. Hammock Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4403–4408. Published online 2001 April 3. doi: 10.1073/pnas.071047998.PMCID: PMC31847 From the Cover: Structure and function of the C-terminal PABC domain of human
poly(A)-binding protein Guennadi Kozlov, Jean-François Trempe, Kianoush Khaleghpour, Avak Kahvejian, Irena Ekiel, and Kalle Gehring Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4409–4413. Published online 2001 April 3. doi: 10.1073/pnas.071024998.PMCID: PMC31848 Biophysics From the Cover: X-ray structure of the human hyperplastic discs protein: An
ortholog of the C-terminal domain of poly(A)-binding protein Rahul C. Deo, Nahum Sonenberg, and Stephen K. Burley Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4414–4419. Published online 2001 April 3. doi: 10.1073/pnas.071552198.PMCID: PMC31849 Noninvasive functional optical spectroscopy of human
breast tissue Natasha Shah, Albert Cerussi, Charlotta Eker, Jenny Espinoza, John Butler, Joshua Fishkin, Rene Hornung, and Bruce Tromberg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4420–4425. Published online 2001 April 3. doi: 10.1073/pnas.071511098.PMCID: PMC31850 Deuterium isotope effect on the intramolecular electron transfer
in Pseudomonas aeruginosa azurin Ole Farver, Jingdong Zhang, Qijin Chi, Israel Pecht, and Jens Ulstrup Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4426–4430. Published online 2001 April 3. doi: 10.1073/pnas.071043798.PMCID: PMC31851 Prion protein: Evolution caught en route P. Tompa, G. E. Tusnády, M. Cserző, and I. Simon Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4431–4436. Published online 2001 April 3. doi: 10.1073/pnas.071308398.PMCID: PMC31852 Evidence for two active branches for electron transfer in
photosystem I Mariana Guergova-Kuras, Brent Boudreaux, Anne Joliot, Pierre Joliot, and Kevin Redding Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4437–4442. Published online 2001 March 27. doi: 10.1073/pnas.081078898.PMCID: PMC31853 Cell Biology Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for
jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation Sharath K. Rai, Fuh-Mei Duh, Vladimir Vigdorovich, Alla Danilkovitch-Miagkova, Michael I. Lerman, and A. Dusty Miller Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4443–4448. doi: 10.1073/pnas.071572898.PMCID: PMC31854 Direct transformation of rodent fibroblasts by jaagsiekte sheep
retrovirus DNA Naoyoshi Maeda, Massimo Palmarini, Claudio Murgia, and Hung Fan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4449–4454. doi: 10.1073/pnas.071547598.PMCID: PMC31855 p19ARF targets certain E2F species for degradation Fabio Martelli, Timothy Hamilton, Daniel P. Silver, Norman E. Sharpless, Nabeel Bardeesy, Mihail Rokas, Ronald A. DePinho, David M. Livingston, and Steven R. Grossman Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4455–4460. Published online 2001 March 27. doi: 10.1073/pnas.081061398.PMCID: PMC31856 IL-1-induced NFκB and c-Jun N-terminal kinase (JNK) activation
diverge at IL-1 receptor-associated kinase (IRAK) Xiaoxia Li, Mairead Commane, Zhengfan Jiang, and George R. Stark Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4461–4465. Published online 2001 April 3. doi: 10.1073/pnas.071054198.PMCID: PMC31857 Cessation of rapid late endosomal tubulovesicular trafficking in
Niemann–Pick type C1 disease Mei Zhang, Nancy K. Dwyer, Dona C. Love, Adele Cooney, Marcy Comly, Edward Neufeld, Peter G. Pentchev, E. Joan Blanchette-Mackie, and John A. Hanover Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4466–4471. doi: 10.1073/pnas.081070898.PMCID: PMC31858 Extracellular matrix composition determines the transcriptional
response to epidermal growth factor receptor activation Stephen J. Yarwood and James R. Woodgett Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4472–4477. Published online 2001 April 3. doi: 10.1073/pnas.081069098.PMCID: PMC31859 INAUGURAL ARTICLE by a Recently Elected Academy Member: Biomechanical activation of vascular endothelium as a determinant
of its functional phenotype Guillermo García-Cardeña, Jason Comander, Keith R. Anderson, Brett R. Blackman, and Michael A. Gimbrone, Jr. Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4478–4485. doi: 10.1073/pnas.071052598.PMCID: PMC31860 Multicopy plasmids are clustered and localized in
Escherichia coli Joe Pogliano, Thanh Quoc Ho, Zhenping Zhong, and Donald R. Helinski Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4486–4491. Published online 2001 March 27. doi: 10.1073/pnas.081075798.PMCID: PMC31861 Mammalian mad2 and bub1/bubR1 recognize distinct
spindle-attachment and kinetochore-tension checkpoints Dimitrios A. Skoufias, Paul R. Andreassen, Françoise B. Lacroix, Leslie Wilson, and Robert L. Margolis Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4492–4497. Published online 2001 March 27. doi: 10.1073/pnas.081076898.PMCID: PMC31862 Expression of the telomerase catalytic subunit, hTERT, induces
resistance to transforming growth factor β growth inhibition in
p16INK4A(−) human mammary epithelial cells Martha R. Stampfer, James Garbe, Gerri Levine, Serge Lichtsteiner, Alain P. Vasserot, and Paul Yaswen Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4498–4503. Published online 2001 April 3. doi: 10.1073/pnas.071483998.PMCID: PMC31863 Migration of keratinocytes through tunnels of digested fibrin Vincent Ronfard and Yann Barrandon Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4504–4509. Published online 2001 March 27. doi: 10.1073/pnas.071631698.PMCID: PMC31864 Myc represses the p21(WAF1/CIP1) promoter and
interacts with Sp1/Sp3 Andrei L. Gartel, Xin Ye, Eugene Goufman, Pavel Shianov, Nissim Hay, Feridoon Najmabadi, and Angela L. Tyner Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4510–4515. Published online 2001 March 27. doi: 10.1073/pnas.081074898.PMCID: PMC31865 Differentiation of embryonic mesenchymal cells to
odontoblast-like cells by overexpression of dentin
matrix protein 1 Karthikeyan Narayanan, Rampalli Srinivas, Amsaveni Ramachandran, Jianjun Hao, Bruce Quinn, and Anne George Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4516–4521. Published online 2001 April 3. doi: 10.1073/pnas.081075198.PMCID: PMC31866 Developmental Biology Roles for genomic imprinting and the zygotic genome in
placental development Pantelis Georgiades, Marie Watkins, Graham J. Burton, and Anne C. Ferguson-Smith Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4522–4527. Published online 2001 March 27. doi: 10.1073/pnas.081540898.PMCID: PMC31867 Spatial and temporal emergence of high proliferative potential
hematopoietic precursors during murine embryogenesis J. Palis, R. J. Chan, A. Koniski, R. Patel, M. Starr, and M. C. Yoder Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4528–4533. doi: 10.1073/pnas.071002398.PMCID: PMC31868 Ecology Multiscale assessment of patterns of avian species richness Carsten Rahbek and Gary R. Graves Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4534–4539. doi: 10.1073/pnas.071034898.PMCID: PMC31869 Galactosides in the rhizosphere: Utilization by
Sinorhizobium meliloti and development of
a biosensor Ryan M. Bringhurst, Zoe G. Cardon, and Daniel J. Gage Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4540–4545. Published online 2001 March 27. doi: 10.1073/pnas.071375898.PMCID: PMC31870 Evolution From the Cover: Global biodiversity and the ancient carbon cycle Daniel H. Rothman Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4305–4310. doi: 10.1073/pnas.071047798.PMCID: PMC31829 Structures of two molluscan hemocyanin genes: Significance for
gene evolution Bernhard Lieb, Benjamin Altenhein, Jürgen Markl, Alexandra Vincent, Erin van Olden, Kensal E. van Holde, and Karen I. Miller Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4546–4551. Published online 2001 April 3. doi: 10.1073/pnas.071049998.PMCID: PMC31871 Directed evolution of polymerase function by
compartmentalized self-replication Farid J. Ghadessy, Jennifer L. Ong, and Philipp Holliger Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4552–4557. Published online 2001 March 27. doi: 10.1073/pnas.071052198.PMCID: PMC31872 From the Cover: Biogeographic range expansion into South America by
Coccidioides immitis mirrors New World patterns of
human migration Matthew C. Fisher, Gina L. Koenig, Thomas J. White, Gioconda San-Blas, Ricardo Negroni, Isidro Gutiérrez Alvarez, Bodo Wanke, and John W. Taylor Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4558–4562. Published online 2001 April 3. doi: 10.1073/pnas.071406098.PMCID: PMC31873 Maximum likelihood estimation of a migration matrix and effective
population sizes in n subpopulations by using a
coalescent approach Peter Beerli and Joseph Felsenstein Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4563–4568. Published online 2001 April 3. doi: 10.1073/pnas.081068098.PMCID: PMC31874 Genetics A comprehensive two-hybrid analysis to explore the yeast
protein interactome Takashi Ito, Tomoko Chiba, Ritsuko Ozawa, Mikio Yoshida, Masahira Hattori, and Yoshiyuki Sakaki Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4569–4574. Published online 2001 March 13. doi: 10.1073/pnas.061034498.PMCID: PMC31875 ANX7, a candidate tumor suppressor gene for prostate cancer Meera Srivastava, Lukas Bubendorf, Vasantha Srikantan, Linda Fossom, Lisa Nolan, Mirta Glasman, Ximena Leighton, Wilfred Fehrle, Stefania Pittaluga, Mark Raffeld, Pasi Koivisto, Niels Willi, Thomas C. Gasser, Juha Kononen, Guido Sauter, Olli P. Kallioniemi, Shiv Srivastava, and Harvey B. Pollard Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4575–4580. Published online 2001 April 3. doi: 10.1073/pnas.071055798.PMCID: PMC31876 Selective ablation of retinoid X receptor α in hepatocytes
impairs their lifespan and regenerative capacity Takeshi Imai, Ming Jiang, Philippe Kastner, Pierre Chambon, and Daniel Metzger Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4581–4586. Published online 2001 April 3. doi: 10.1073/pnas.071056098.PMCID: PMC31877 Immunology Localization of CD4+ T cell epitope hotspots to
exposed strands of HIV envelope glycoprotein suggests structural
influences on antigen processing Sherri Surman, Timothy D. Lockey, Karen S. Slobod, Bart Jones, Janice M. Riberdy, Stephen W. White, Peter C. Doherty, and Julia L. Hurwitz Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4587–4592. Published online 2001 April 3. doi: 10.1073/pnas.071063898.PMCID: PMC31878 Immucillin H, a powerful transition-state analog inhibitor of
purine nucleoside phosphorylase, selectively inhibits human
T lymphocytes Greg A. Kicska, Li Long, Heidi Hörig, Craig Fairchild, Peter C. Tyler, Richard H. Furneaux, Vern L. Schramm, and Howard L. Kaufman Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4593–4598. Published online 2001 April 3. doi: 10.1073/pnas.071050798.PMCID: PMC31879 Role of MEKK2-MEK5 in the regulation of TNF-α gene
expression and MEKK2-MKK7 in the activation of c-Jun N-terminal
kinase in mast cells Kosuke Chayama, Philip J. Papst, Timothy P. Garrington, Joanne C. Pratt, Tamotsu Ishizuka, Saiphone Webb, Soula Ganiatsas, Leonard I. Zon, Weiyong Sun, Gary L. Johnson, and Erwin W. Gelfand Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4599–4604. Published online 2001 March 27. doi: 10.1073/pnas.081021898.PMCID: PMC31880 Medical Sciences Comparative evaluation of the antitumor activity of
antiangiogenic proteins delivered by gene transfer Calvin J. Kuo, Filip Farnebo, Evan Y. Yu, Rolf Christofferson, Rebecca A. Swearingen, Robert Carter, Horst A. von Recum, Jenny Yuan, Junne Kamihara, Evelyn Flynn, Robert D'Amato, Judah Folkman, and Richard C. Mulligan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4605–4610. Published online 2001 March 27. doi: 10.1073/pnas.081615298.PMCID: PMC31881 An important function of Nrf2 in combating oxidative stress:
Detoxification of acetaminophen Kaimin Chan, Xiao-Dong Han, and Yuet Wai Kan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4611–4616. Published online 2001 April 3. doi: 10.1073/pnas.081082098.PMCID: PMC31882 Correlation of breath ammonia with blood urea nitrogen and
creatinine during hemodialysis L. R. Narasimhan, William Goodman, and C. Kumar N. Patel Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4617–4621. doi: 10.1073/pnas.071057598.PMCID: PMC31883 PTEN controls tumor-induced angiogenesis Shenghua Wen, Javor Stolarov, Michael P. Myers, Jing Dong Su, Michael H. Wigler, Nicholas K. Tonks, and Donald L. Durden Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4622–4627. Published online 2001 March 27. doi: 10.1073/pnas.081063798.PMCID: PMC31884 Role of tumor–host interactions in interstitial diffusion of
macromolecules: Cranial vs. subcutaneous tumors Alain Pluen, Yves Boucher, Saroja Ramanujan, Trevor D. McKee, Takeshi Gohongi, Emmanuelle di Tomaso, Edward B. Brown, Yotaro Izumi, Robert B. Campbell, David A. Berk, and Rakesh K. Jain Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4628–4633. Published online 2001 March 27. doi: 10.1073/pnas.081626898.PMCID: PMC31885 From the Cover: Retroviral RNA identified in the cerebrospinal fluids and brains
of individuals with schizophrenia Håkan Karlsson, Silke Bachmann, Johannes Schröder, Justin McArthur, E. Fuller Torrey, and Robert H. Yolken Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4634–4639. doi: 10.1073/pnas.061021998.PMCID: PMC31886 A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and
PTEN antagonizes tumor necrosis factor inhibition of insulin
signaling through insulin receptor substrate-1 Osman Nidai Ozes, Hakan Akca, Lindsey D. Mayo, Jason A. Gustin, Tomohiko Maehama, Jack E. Dixon, and David B. Donner Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4640–4645. Published online 2001 April 3. doi: 10.1073/pnas.051042298.PMCID: PMC31887 Antisense-mediated depletion of p300 in human cells leads to
premature G1 exit and up-regulation
of c-MYC Sivanagarani Kolli, Ann Marie Buchmann, Justin Williams, Sigmund Weitzman, and Bayar Thimmapaya Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4646–4651. doi: 10.1073/pnas.081141998.PMCID: PMC31888 From the Cover: Ciliary neurotrophic factor activates leptin-like pathways and
reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity P. D. Lambert, K. D. Anderson, M. W. Sleeman, V. Wong, J. Tan, A. Hijarunguru, T. L. Corcoran, J. D. Murray, K. E. Thabet, G. D. Yancopoulos, and S. J. Wiegand Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4652–4657. Published online 2001 March 20. doi: 10.1073/pnas.061034298.PMCID: PMC31889 Microbiology Complete genome sequence of an M1 strain of
Streptococcus pyogenes Joseph J. Ferretti, William M. McShan, Dragana Ajdic, Dragutin J. Savic, Gorana Savic, Kevin Lyon, Charles Primeaux, Steven Sezate, Alexander N. Suvorov, Steve Kenton, Hong Shing Lai, Shao Ping Lin, Yudong Qian, Hong Gui Jia, Fares Z. Najar, Qun Ren, Hua Zhu, Lin Song, Jim White, Xiling Yuan, Sandra W. Clifton, Bruce A. Roe, and Robert McLaughlin Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4658–4663. doi: 10.1073/pnas.071559398.PMCID: PMC31890 Purification and characterization of an autoregulatory substance
capable of regulating the morphological transition in
Candida albicans Ki-Bong Oh, Hiroshi Miyazawa, Toshimichi Naito, and Hideaki Matsuoka Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4664–4668. Published online 2001 March 27. doi: 10.1073/pnas.071404698.PMCID: PMC31891 Polymerization of a single protein of the pathogen
Yersinia enterocolitica into needles punctures
eukaryotic cells Egbert Hoiczyk and Günter Blobel Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4669–4674. Published online 2001 April 3. doi: 10.1073/pnas.071065798.PMCID: PMC31892 Epstein–Barr virus latent-infection membrane proteins are
palmitoylated and raft-associated: Protein 1 binds to the
cytoskeleton through TNF receptor cytoplasmic factors Masaya Higuchi, Kenneth M. Izumi, and Elliott Kieff Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4675–4680. doi: 10.1073/pnas.081075298.PMCID: PMC31893 Proteomic analysis of the bacterial cell cycle Björn Grünenfelder, Gabriele Rummel, Jiri Vohradsky, Daniel Röder, Hanno Langen, and Urs Jenal Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4681–4686. Published online 2001 April 3. doi: 10.1073/pnas.071538098.PMCID: PMC31894 Neurobiology Mechanisms of migraine aura revealed by functional MRI in human
visual cortex Nouchine Hadjikhani, Margarita Sanchez del Rio, Ona Wu, Denis Schwartz, Dick Bakker, Bruce Fischl, Kenneth K. Kwong, F. Michael Cutrer, Bruce R. Rosen, Roger B. H. Tootell, A. Gregory Sorensen, and Michael A. Moskowitz Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4687–4692. Published online 2001 April 3. doi: 10.1073/pnas.071582498.PMCID: PMC31895 Rethinking the role of phosducin: Light-regulated binding of
phosducin to 14-3-3 in rod inner segments Koichi Nakano, Jing Chen, George E. Tarr, Tatsuro Yoshida, Julia M. Flynn, and Mark W. Bitensky Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4693–4698. Published online 2001 April 3. doi: 10.1073/pnas.071067198.PMCID: PMC31896 Allosteric modulation of Ca2+ channels by G proteins,
voltage-dependent facilitation, protein kinase C, and
Cavβ subunits Stefan Herlitze, Huijun Zhong, Todd Scheuer, and William A. Catterall Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4699–4704. doi: 10.1073/pnas.051628998.PMCID: PMC31897 Control of gating mode by a single amino acid residue in
transmembrane segment IS3 of the N-type Ca2+ channel Huijun Zhong, Bin Li, Todd Scheuer, and William A. Catterall Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4705–4709. doi: 10.1073/pnas.051629098.PMCID: PMC31898 Neurogenesis in dentate subgranular zone and rostral
subventricular zone after focal cerebral ischemia in the rat Kunlin Jin, Manabu Minami, Jing Q. Lan, Xiao Ou Mao, Sophie Batteur, Roger P. Simon, and David A. Greenberg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4710–4715. doi: 10.1073/pnas.081011098.PMCID: PMC31899 Lack of tissue glucocorticoid reactivation in
11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates
age-related learning impairments Joyce L. W. Yau, June Noble, Christopher J. Kenyon, Carina Hibberd, Yuri Kotelevtsev, John J. Mullins, and Jonathan R. Seckl Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4716–4721. Published online 2001 March 27. doi: 10.1073/pnas.071562698.PMCID: PMC31900 F-spondin is a contact-repellent molecule for embryonic
motor neurons Vered Tzarfati-Majar, Tal Burstyn-Cohen, and Avihu Klar Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4722–4727. Published online 2001 April 3. doi: 10.1073/pnas.081062398.PMCID: PMC31901 Effect of nicotine on brain activation during performance of a
working memory task Monique Ernst, John A. Matochik, Stephen J. Heishman, John D. Van Horn, Peter H. Jons, Jack E. Henningfield, and Edythe D. London Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4728–4733. Published online 2001 March 27. doi: 10.1073/pnas.061369098.PMCID: PMC31902 β-Amyloid peptide blocks the response of α7-containing
nicotinic receptors on hippocampal neurons Qing-song Liu, Hideki Kawai, and Darwin K. Berg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4734–4739. Published online 2001 March 27. doi: 10.1073/pnas.081553598.PMCID: PMC31903 Diacylglycerol kinase regulates seizure
susceptibility and long-term potentiation through
arachidonoyl– inositol lipid signaling Elena B. Rodriguez de Turco, Wen Tang, Matthew K. Topham, Fumio Sakane, Victor L. Marcheselli, Chu Chen, Akinobu Taketomi, Stephen M. Prescott, and Nicolas G. Bazan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4740–4745. Published online 2001 April 3. doi: 10.1073/pnas.081536298.PMCID: PMC31904 Genome-wide expression analysis reveals dysregulation of
myelination-related genes in chronic schizophrenia Yaron Hakak, John R. Walker, Cheng Li, Wing Hung Wong, Kenneth L. Davis, Joseph D. Buxbaum, Vahram Haroutunian, and Allen A. Fienberg Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4746–4751. doi: 10.1073/pnas.081071198.PMCID: PMC31905 The generation, migration, and differentiation of olfactory
neurons in the adult primate brain David R. Kornack and Pasko Rakic Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4752–4757. doi: 10.1073/pnas.081074998.PMCID: PMC31906 Regulation of neuroblast mitosis is determined by PACAP receptor
isoform expression Arnaud Nicot and Emanuel DiCicco-Bloom Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4758–4763. doi: 10.1073/pnas.071465398.PMCID: PMC31907 Human single-chain Fv intrabodies counteract in
situ huntingtin aggregation in cellular models of
Huntington's disease Jean-Michel Lecerf, Thomas L. Shirley, Quan Zhu, Aleksey Kazantsev, Peter Amersdorfer, David E. Housman, Anne Messer, and James S. Huston Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4764–4769. doi: 10.1073/pnas.071058398.PMCID: PMC31908 Physiology Allostatic load as a marker of cumulative biological risk:
MacArthur studies of successful aging Teresa E. Seeman, Bruce S. McEwen, John W. Rowe, and Burton H. Singer Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4770–4775. Published online 2001 April 3. doi: 10.1073/pnas.081072698.PMCID: PMC31909 Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in
Ca2+-dependent activation Shumin Bian, Isabelle Favre, and Edward Moczydlowski Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4776–4781. Published online 2001 March 27. doi: 10.1073/pnas.081072398.PMCID: PMC31910 Plant Biology A postgermination developmental arrest checkpoint is mediated by
abscisic acid and requires the ABI5 transcription factor in
Arabidopsis Luis Lopez-Molina, Sébastien Mongrand, and Nam-Hai Chua Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4782–4787. Published online 2001 April 3. doi: 10.1073/pnas.081594298.PMCID: PMC31911 Jasmonic acid carboxyl methyltransferase: A key enzyme for
jasmonate-regulated plant responses Hak Soo Seo, Jong Tae Song, Jong-Joo Cheong, Yong-Hwan Lee, Yin-Won Lee, Ingyu Hwang, Jong Seob Lee, and Yang Do Choi Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4788–4793. Published online 2001 April 3. doi: 10.1073/pnas.081557298.PMCID: PMC31912 A strategy for the identification of proteins targeted
by thioredoxin Hiroyuki Yano, Joshua H. Wong, Young Moo Lee, Myeong-Je Cho, and Bob B. Buchanan Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4794–4799. Published online 2001 March 27. doi: 10.1073/pnas.071041998.PMCID: PMC31913 Psychology Effects of temporal association on recognition memory Guy Wallis and Heinrich H. Bülthoff Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4800–4804. Published online 2001 April 3. doi: 10.1073/pnas.071028598.PMCID: PMC31914 Can medial temporal lobe regions distinguish true from false? An
event-related functional MRI study of veridical and illusory
recognition memory Roberto Cabeza, Stephen M. Rao, Anthony D. Wagner, Andrew R. Mayer, and Daniel L. Schacter Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4805–4810. Published online 2001 April 3. doi: 10.1073/pnas.081082698.PMCID: PMC31915 Social Sciences Psychology Effects of temporal association on recognition memory Guy Wallis and Heinrich H. Bülthoff Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4800–4804. Published online 2001 April 3. doi: 10.1073/pnas.071028598.PMCID: PMC31914 On a psychophysical transformed-rule up and down method
converging on a 75% level of correct responses Jozef J. Zwislocki and Evan M. Relkin Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4811–4814. Published online 2001 April 3. doi: 10.1073/pnas.081082598.PMCID: PMC31916 Corrections Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. Published online 2001 April 3. doi: 10.1073/pnas.081082198.PMCID: PMC55945 Corrects: Gunilla B. Toth, et al. Water-borne cues induce chemical defense in a marine alga
(Ascophyllum nodosum). Proc Natl Acad Sci U S A. 2000 December 19; 97(26): 14418–14420. Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. Published online 2001 April 3. doi: 10.1073/pnas.091112698.PMCID: PMC55946 Corrects: John D. Rummel. Special Feature: Planetary exploration in the time of astrobiology: Protecting
against biological contamination. Proc Natl Acad Sci U S A. 2001 February 27; 98(5): 2128–2131. Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. doi: 10.1073/pnas.091112798.PMCID: PMC55947 Corrects: Pierre Colas, et al. Targeted modification and transportation of cellular proteins. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13720–13725. |