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Volume 98(8);  April 10, 2001
Commentaries
Networking proteins in yeast
Tony R. Hazbun and Stanley Fields
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4277–4278. doi: 10.1073/pnas.091096398.
PMCID: PMC33318
Circumventing leptin resistance for weight control
Satya P. Kalra
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4279–4281. doi: 10.1073/pnas.091101498.
PMCID: PMC33319
Who's got pull around here? Cell organization in development and tissue engineering
D. A. Lauffenburger and L. G. Griffith
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4282–4284. doi: 10.1073/pnas.081083698.
PMCID: PMC33320
New transformation tricks from a barnyard retrovirus: Implications for human lung cancer
Naomi Rosenberg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4285–4287. doi: 10.1073/pnas.091097698.
PMCID: PMC33321
Delivering messages from the 3′ end
Gabriele Varani
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4288–4289. doi: 10.1073/pnas.091108098.
PMCID: PMC33322
Biological diversity and resource plunder in the geological record: Casual correlations or causal relationships?
Paul G. Falkowski and Yair Rosenthal
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4290–4292. doi: 10.1073/pnas.091096798.
PMCID: PMC33323
Retroviruses and the pathogenesis of schizophrenia
David A. Lewis
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4293–4294. doi: 10.1073/pnas.081075898.
PMCID: PMC33324
Perspective
The many ways to cross the plasma membrane
David J. Stephens and Rainer Pepperkok
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4295–4298. Published online 2001 March 27. doi: 10.1073/pnas.081065198.
PMCID: PMC33325
Physical Sciences
Chemistry
On the absorbance changes in the photocycle of the photoactive yellow protein: A quantum-chemical analysis
Vicent Molina and Manuela Merchán
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4299–4304. Published online 2001 April 3. doi: 10.1073/pnas.071058098.
PMCID: PMC31828
Geology
From the Cover:
Global biodiversity and the ancient carbon cycle
Daniel H. Rothman
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4305–4310. doi: 10.1073/pnas.071047798.
PMCID: PMC31829
Mathematics
Behavior of several two-dimensional fluid equations in singular scenarios
Diego Cordoba and Charles Fefferman
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4311–4312. Published online 2001 March 27. doi: 10.1073/pnas.061038998.
PMCID: PMC31830
A positivity result in the theory of Macdonald polynomials
A. M. Garsia and J. Haglund
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4313–4316. Published online 2001 March 27. doi: 10.1073/pnas.071043398.
PMCID: PMC31831
Biological Sciences
Anthropology
A molecular analysis of dietary diversity for three archaic Native Americans
Hendrik N. Poinar, Melanie Kuch, Kristin D. Sobolik, Ian Barnes, Artur B. Stankiewicz, Tomasz Kuder, W. Geofferey Spaulding, Vaughn M. Bryant, Alan Cooper, and Svante Pääbo
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4317–4322. doi: 10.1073/pnas.061014798.
PMCID: PMC31832
Applied Biological Sciences
Tissue spreading on implantable substrates is a competitive outcome of cell–cell vs. cell–substratum adhesivity
Peter L. Ryan, Ramsey A. Foty, Joachim Kohn, and Malcolm S. Steinberg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4323–4327. Published online 2001 March 27. doi: 10.1073/pnas.071615398.
PMCID: PMC31833
Biochemistry
Translocation pathway of protein substrates in ClpAP protease
Takashi Ishikawa, Fabienne Beuron, Martin Kessel, Sue Wickner, Michael R. Maurizi, and Alasdair C. Steven
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4328–4333. Published online 2001 April 3. doi: 10.1073/pnas.081543698.
PMCID: PMC31834
A role for intermolecular disulfide bonds in prion diseases?
Ervin Welker, William J. Wedemeyer, and Harold A. Scheraga
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4334–4336. Published online 2001 March 27. doi: 10.1073/pnas.071066598.
PMCID: PMC31835
Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase
Masahiro Fujihashi, Yuan-Wei Zhang, Yoshiki Higuchi, Xiao-Yuan Li, Tanetoshi Koyama, and Kunio Miki
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4337–4342. Published online 2001 April 3. doi: 10.1073/pnas.071514398.
PMCID: PMC31836
Toward rules for 1:1 polyamide:DNA recognition
Adam R. Urbach and Peter B. Dervan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4343–4348. doi: 10.1073/pnas.081070798.
PMCID: PMC31837
Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution
Steven L. Kazmirski, Kam-Bo Wong, Stefan M. V. Freund, Yee-Joo Tan, Alan R. Fersht, and Valerie Daggett
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4349–4354. Published online 2001 March 27. doi: 10.1073/pnas.071054398.
PMCID: PMC31838
The thermodynamic origin of the stability of a thermophilic ribozyme
X.-W. Fang, B. L. Golden, K. Littrell, V. Shelton, P. Thiyagarajan, T. Pan, and T. R. Sosnick
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4355–4360. doi: 10.1073/pnas.071050698.
PMCID: PMC31839
Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2
Thomas Wendt, Dianne Taylor, Kathleen M. Trybus, and Kenneth Taylor
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4361–4366. Published online 2001 April 3. doi: 10.1073/pnas.071051098.
PMCID: PMC31840
Prediction of protein deamidation rates from primary and three-dimensional structure
Noah E. Robinson and Arthur B. Robinson
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4367–4372. doi: 10.1073/pnas.071066498.
PMCID: PMC31841
Chrysanthemyl diphosphate synthase: Isolation of the gene and characterization of the recombinant non-head-to-tail monoterpene synthase from Chrysanthemum cinerariaefolium
Susan B. Rivera, Bradley D. Swedlund, Gretchen J. King, Russell N. Bell, Charles E. Hussey, Jr., Donna M. Shattuck-Eidens, Wislawa M. Wrobel, Galen D. Peiser, and C. Dale Poulter
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4373–4378. Published online 2001 April 3. doi: 10.1073/pnas.071543598.
PMCID: PMC31842
Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain
Stefan N. Constantinescu, Tzvia Keren, Merav Socolovsky, Hyung-song Nam, Yoav I. Henis, and Harvey F. Lodish
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4379–4384. doi: 10.1073/pnas.081069198.
PMCID: PMC31843
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1
Yoshiro Otsuki, Masamitsu Tanaka, Shigeto Yoshii, Nobuko Kawazoe, Kazuyasu Nakaya, and Haruhiko Sugimura
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4385–4390. Published online 2001 March 27. doi: 10.1073/pnas.071411598.
PMCID: PMC31844
HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1
Jiansheng Wu, Andrew A. Carmen, Ryuji Kobayashi, Noriyuki Suka, and Michael Grunstein
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4391–4396. Published online 2001 April 3. doi: 10.1073/pnas.081560698.
PMCID: PMC31845
A ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO)-like protein from Chlorobium tepidum that is involved with sulfur metabolism and the response to oxidative stress
Thomas E. Hanson and F. Robert Tabita
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4397–4402. Published online 2001 April 3. doi: 10.1073/pnas.081610398.
PMCID: PMC31846
Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry
Masahiro Miyashita, Jack M. Presley, Bruce A. Buchholz, Kit S. Lam, Young Moo Lee, John S. Vogel, and Bruce D. Hammock
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4403–4408. Published online 2001 April 3. doi: 10.1073/pnas.071047998.
PMCID: PMC31847
From the Cover:
Structure and function of the C-terminal PABC domain of human poly(A)-binding protein
Guennadi Kozlov, Jean-François Trempe, Kianoush Khaleghpour, Avak Kahvejian, Irena Ekiel, and Kalle Gehring
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4409–4413. Published online 2001 April 3. doi: 10.1073/pnas.071024998.
PMCID: PMC31848
Biophysics
From the Cover:
X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein
Rahul C. Deo, Nahum Sonenberg, and Stephen K. Burley
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4414–4419. Published online 2001 April 3. doi: 10.1073/pnas.071552198.
PMCID: PMC31849
Noninvasive functional optical spectroscopy of human breast tissue
Natasha Shah, Albert Cerussi, Charlotta Eker, Jenny Espinoza, John Butler, Joshua Fishkin, Rene Hornung, and Bruce Tromberg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4420–4425. Published online 2001 April 3. doi: 10.1073/pnas.071511098.
PMCID: PMC31850
Deuterium isotope effect on the intramolecular electron transfer in Pseudomonas aeruginosa azurin
Ole Farver, Jingdong Zhang, Qijin Chi, Israel Pecht, and Jens Ulstrup
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4426–4430. Published online 2001 April 3. doi: 10.1073/pnas.071043798.
PMCID: PMC31851
Prion protein: Evolution caught en route
P. Tompa, G. E. Tusnády, M. Cserző, and I. Simon
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4431–4436. Published online 2001 April 3. doi: 10.1073/pnas.071308398.
PMCID: PMC31852
Evidence for two active branches for electron transfer in photosystem I
Mariana Guergova-Kuras, Brent Boudreaux, Anne Joliot, Pierre Joliot, and Kevin Redding
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4437–4442. Published online 2001 March 27. doi: 10.1073/pnas.081078898.
PMCID: PMC31853
Cell Biology
Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
Sharath K. Rai, Fuh-Mei Duh, Vladimir Vigdorovich, Alla Danilkovitch-Miagkova, Michael I. Lerman, and A. Dusty Miller
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4443–4448. doi: 10.1073/pnas.071572898.
PMCID: PMC31854
Direct transformation of rodent fibroblasts by jaagsiekte sheep retrovirus DNA
Naoyoshi Maeda, Massimo Palmarini, Claudio Murgia, and Hung Fan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4449–4454. doi: 10.1073/pnas.071547598.
PMCID: PMC31855
p19ARF targets certain E2F species for degradation
Fabio Martelli, Timothy Hamilton, Daniel P. Silver, Norman E. Sharpless, Nabeel Bardeesy, Mihail Rokas, Ronald A. DePinho, David M. Livingston, and Steven R. Grossman
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4455–4460. Published online 2001 March 27. doi: 10.1073/pnas.081061398.
PMCID: PMC31856
IL-1-induced NFκB and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)
Xiaoxia Li, Mairead Commane, Zhengfan Jiang, and George R. Stark
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4461–4465. Published online 2001 April 3. doi: 10.1073/pnas.071054198.
PMCID: PMC31857
Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease
Mei Zhang, Nancy K. Dwyer, Dona C. Love, Adele Cooney, Marcy Comly, Edward Neufeld, Peter G. Pentchev, E. Joan Blanchette-Mackie, and John A. Hanover
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4466–4471. doi: 10.1073/pnas.081070898.
PMCID: PMC31858
Extracellular matrix composition determines the transcriptional response to epidermal growth factor receptor activation
Stephen J. Yarwood and James R. Woodgett
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4472–4477. Published online 2001 April 3. doi: 10.1073/pnas.081069098.
PMCID: PMC31859
Biomechanical activation of vascular endothelium as a determinant of its functional phenotype
Guillermo García-Cardeña, Jason Comander, Keith R. Anderson, Brett R. Blackman, and Michael A. Gimbrone, Jr.
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4478–4485. doi: 10.1073/pnas.071052598.
PMCID: PMC31860
Multicopy plasmids are clustered and localized in Escherichia coli
Joe Pogliano, Thanh Quoc Ho, Zhenping Zhong, and Donald R. Helinski
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4486–4491. Published online 2001 March 27. doi: 10.1073/pnas.081075798.
PMCID: PMC31861
Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints
Dimitrios A. Skoufias, Paul R. Andreassen, Françoise B. Lacroix, Leslie Wilson, and Robert L. Margolis
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4492–4497. Published online 2001 March 27. doi: 10.1073/pnas.081076898.
PMCID: PMC31862
Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor β growth inhibition in p16INK4A(−) human mammary epithelial cells
Martha R. Stampfer, James Garbe, Gerri Levine, Serge Lichtsteiner, Alain P. Vasserot, and Paul Yaswen
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4498–4503. Published online 2001 April 3. doi: 10.1073/pnas.071483998.
PMCID: PMC31863
Migration of keratinocytes through tunnels of digested fibrin
Vincent Ronfard and Yann Barrandon
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4504–4509. Published online 2001 March 27. doi: 10.1073/pnas.071631698.
PMCID: PMC31864
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
Andrei L. Gartel, Xin Ye, Eugene Goufman, Pavel Shianov, Nissim Hay, Feridoon Najmabadi, and Angela L. Tyner
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4510–4515. Published online 2001 March 27. doi: 10.1073/pnas.081074898.
PMCID: PMC31865
Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1
Karthikeyan Narayanan, Rampalli Srinivas, Amsaveni Ramachandran, Jianjun Hao, Bruce Quinn, and Anne George
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4516–4521. Published online 2001 April 3. doi: 10.1073/pnas.081075198.
PMCID: PMC31866
Developmental Biology
Roles for genomic imprinting and the zygotic genome in placental development
Pantelis Georgiades, Marie Watkins, Graham J. Burton, and Anne C. Ferguson-Smith
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4522–4527. Published online 2001 March 27. doi: 10.1073/pnas.081540898.
PMCID: PMC31867
Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis
J. Palis, R. J. Chan, A. Koniski, R. Patel, M. Starr, and M. C. Yoder
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4528–4533. doi: 10.1073/pnas.071002398.
PMCID: PMC31868
Ecology
Multiscale assessment of patterns of avian species richness
Carsten Rahbek and Gary R. Graves
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4534–4539. doi: 10.1073/pnas.071034898.
PMCID: PMC31869
Galactosides in the rhizosphere: Utilization by Sinorhizobium meliloti and development of a biosensor
Ryan M. Bringhurst, Zoe G. Cardon, and Daniel J. Gage
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4540–4545. Published online 2001 March 27. doi: 10.1073/pnas.071375898.
PMCID: PMC31870
Evolution
From the Cover:
Global biodiversity and the ancient carbon cycle
Daniel H. Rothman
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4305–4310. doi: 10.1073/pnas.071047798.
PMCID: PMC31829
Structures of two molluscan hemocyanin genes: Significance for gene evolution
Bernhard Lieb, Benjamin Altenhein, Jürgen Markl, Alexandra Vincent, Erin van Olden, Kensal E. van Holde, and Karen I. Miller
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4546–4551. Published online 2001 April 3. doi: 10.1073/pnas.071049998.
PMCID: PMC31871
Directed evolution of polymerase function by compartmentalized self-replication
Farid J. Ghadessy, Jennifer L. Ong, and Philipp Holliger
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4552–4557. Published online 2001 March 27. doi: 10.1073/pnas.071052198.
PMCID: PMC31872
From the Cover:
Biogeographic range expansion into South America by Coccidioides immitis mirrors New World patterns of human migration
Matthew C. Fisher, Gina L. Koenig, Thomas J. White, Gioconda San-Blas, Ricardo Negroni, Isidro Gutiérrez Alvarez, Bodo Wanke, and John W. Taylor
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4558–4562. Published online 2001 April 3. doi: 10.1073/pnas.071406098.
PMCID: PMC31873
Maximum likelihood estimation of a migration matrix and effective population sizes in n subpopulations by using a coalescent approach
Peter Beerli and Joseph Felsenstein
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4563–4568. Published online 2001 April 3. doi: 10.1073/pnas.081068098.
PMCID: PMC31874
Genetics
A comprehensive two-hybrid analysis to explore the yeast protein interactome
Takashi Ito, Tomoko Chiba, Ritsuko Ozawa, Mikio Yoshida, Masahira Hattori, and Yoshiyuki Sakaki
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4569–4574. Published online 2001 March 13. doi: 10.1073/pnas.061034498.
PMCID: PMC31875
ANX7, a candidate tumor suppressor gene for prostate cancer
Meera Srivastava, Lukas Bubendorf, Vasantha Srikantan, Linda Fossom, Lisa Nolan, Mirta Glasman, Ximena Leighton, Wilfred Fehrle, Stefania Pittaluga, Mark Raffeld, Pasi Koivisto, Niels Willi, Thomas C. Gasser, Juha Kononen, Guido Sauter, Olli P. Kallioniemi, Shiv Srivastava, and Harvey B. Pollard
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4575–4580. Published online 2001 April 3. doi: 10.1073/pnas.071055798.
PMCID: PMC31876
Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity
Takeshi Imai, Ming Jiang, Philippe Kastner, Pierre Chambon, and Daniel Metzger
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4581–4586. Published online 2001 April 3. doi: 10.1073/pnas.071056098.
PMCID: PMC31877
Immunology
Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing
Sherri Surman, Timothy D. Lockey, Karen S. Slobod, Bart Jones, Janice M. Riberdy, Stephen W. White, Peter C. Doherty, and Julia L. Hurwitz
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4587–4592. Published online 2001 April 3. doi: 10.1073/pnas.071063898.
PMCID: PMC31878
Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes
Greg A. Kicska, Li Long, Heidi Hörig, Craig Fairchild, Peter C. Tyler, Richard H. Furneaux, Vern L. Schramm, and Howard L. Kaufman
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4593–4598. Published online 2001 April 3. doi: 10.1073/pnas.071050798.
PMCID: PMC31879
Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
Kosuke Chayama, Philip J. Papst, Timothy P. Garrington, Joanne C. Pratt, Tamotsu Ishizuka, Saiphone Webb, Soula Ganiatsas, Leonard I. Zon, Weiyong Sun, Gary L. Johnson, and Erwin W. Gelfand
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4599–4604. Published online 2001 March 27. doi: 10.1073/pnas.081021898.
PMCID: PMC31880
Medical Sciences
Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer
Calvin J. Kuo, Filip Farnebo, Evan Y. Yu, Rolf Christofferson, Rebecca A. Swearingen, Robert Carter, Horst A. von Recum, Jenny Yuan, Junne Kamihara, Evelyn Flynn, Robert D'Amato, Judah Folkman, and Richard C. Mulligan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4605–4610. Published online 2001 March 27. doi: 10.1073/pnas.081615298.
PMCID: PMC31881
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
Kaimin Chan, Xiao-Dong Han, and Yuet Wai Kan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4611–4616. Published online 2001 April 3. doi: 10.1073/pnas.081082098.
PMCID: PMC31882
Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis
L. R. Narasimhan, William Goodman, and C. Kumar N. Patel
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4617–4621. doi: 10.1073/pnas.071057598.
PMCID: PMC31883
PTEN controls tumor-induced angiogenesis
Shenghua Wen, Javor Stolarov, Michael P. Myers, Jing Dong Su, Michael H. Wigler, Nicholas K. Tonks, and Donald L. Durden
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4622–4627. Published online 2001 March 27. doi: 10.1073/pnas.081063798.
PMCID: PMC31884
Role of tumor–host interactions in interstitial diffusion of macromolecules: Cranial vs. subcutaneous tumors
Alain Pluen, Yves Boucher, Saroja Ramanujan, Trevor D. McKee, Takeshi Gohongi, Emmanuelle di Tomaso, Edward B. Brown, Yotaro Izumi, Robert B. Campbell, David A. Berk, and Rakesh K. Jain
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4628–4633. Published online 2001 March 27. doi: 10.1073/pnas.081626898.
PMCID: PMC31885
From the Cover:
Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia
Håkan Karlsson, Silke Bachmann, Johannes Schröder, Justin McArthur, E. Fuller Torrey, and Robert H. Yolken
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4634–4639. doi: 10.1073/pnas.061021998.
PMCID: PMC31886
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1
Osman Nidai Ozes, Hakan Akca, Lindsey D. Mayo, Jason A. Gustin, Tomohiko Maehama, Jack E. Dixon, and David B. Donner
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4640–4645. Published online 2001 April 3. doi: 10.1073/pnas.051042298.
PMCID: PMC31887
Antisense-mediated depletion of p300 in human cells leads to premature G1 exit and up-regulation of c-MYC
Sivanagarani Kolli, Ann Marie Buchmann, Justin Williams, Sigmund Weitzman, and Bayar Thimmapaya
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4646–4651. doi: 10.1073/pnas.081141998.
PMCID: PMC31888
From the Cover:
Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity
P. D. Lambert, K. D. Anderson, M. W. Sleeman, V. Wong, J. Tan, A. Hijarunguru, T. L. Corcoran, J. D. Murray, K. E. Thabet, G. D. Yancopoulos, and S. J. Wiegand
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4652–4657. Published online 2001 March 20. doi: 10.1073/pnas.061034298.
PMCID: PMC31889
Microbiology
Complete genome sequence of an M1 strain of Streptococcus pyogenes
Joseph J. Ferretti, William M. McShan, Dragana Ajdic, Dragutin J. Savic, Gorana Savic, Kevin Lyon, Charles Primeaux, Steven Sezate, Alexander N. Suvorov, Steve Kenton, Hong Shing Lai, Shao Ping Lin, Yudong Qian, Hong Gui Jia, Fares Z. Najar, Qun Ren, Hua Zhu, Lin Song, Jim White, Xiling Yuan, Sandra W. Clifton, Bruce A. Roe, and Robert McLaughlin
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4658–4663. doi: 10.1073/pnas.071559398.
PMCID: PMC31890
Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans
Ki-Bong Oh, Hiroshi Miyazawa, Toshimichi Naito, and Hideaki Matsuoka
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4664–4668. Published online 2001 March 27. doi: 10.1073/pnas.071404698.
PMCID: PMC31891
Polymerization of a single protein of the pathogen Yersinia enterocolitica into needles punctures eukaryotic cells
Egbert Hoiczyk and Günter Blobel
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4669–4674. Published online 2001 April 3. doi: 10.1073/pnas.071065798.
PMCID: PMC31892
Epstein–Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: Protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors
Masaya Higuchi, Kenneth M. Izumi, and Elliott Kieff
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4675–4680. doi: 10.1073/pnas.081075298.
PMCID: PMC31893
Proteomic analysis of the bacterial cell cycle
Björn Grünenfelder, Gabriele Rummel, Jiri Vohradsky, Daniel Röder, Hanno Langen, and Urs Jenal
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4681–4686. Published online 2001 April 3. doi: 10.1073/pnas.071538098.
PMCID: PMC31894
Neurobiology
Mechanisms of migraine aura revealed by functional MRI in human visual cortex
Nouchine Hadjikhani, Margarita Sanchez del Rio, Ona Wu, Denis Schwartz, Dick Bakker, Bruce Fischl, Kenneth K. Kwong, F. Michael Cutrer, Bruce R. Rosen, Roger B. H. Tootell, A. Gregory Sorensen, and Michael A. Moskowitz
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4687–4692. Published online 2001 April 3. doi: 10.1073/pnas.071582498.
PMCID: PMC31895
Rethinking the role of phosducin: Light-regulated binding of phosducin to 14-3-3 in rod inner segments
Koichi Nakano, Jing Chen, George E. Tarr, Tatsuro Yoshida, Julia M. Flynn, and Mark W. Bitensky
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4693–4698. Published online 2001 April 3. doi: 10.1073/pnas.071067198.
PMCID: PMC31896
Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Cavβ subunits
Stefan Herlitze, Huijun Zhong, Todd Scheuer, and William A. Catterall
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4699–4704. doi: 10.1073/pnas.051628998.
PMCID: PMC31897
Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel
Huijun Zhong, Bin Li, Todd Scheuer, and William A. Catterall
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4705–4709. doi: 10.1073/pnas.051629098.
PMCID: PMC31898
Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
Kunlin Jin, Manabu Minami, Jing Q. Lan, Xiao Ou Mao, Sophie Batteur, Roger P. Simon, and David A. Greenberg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4710–4715. doi: 10.1073/pnas.081011098.
PMCID: PMC31899
Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments
Joyce L. W. Yau, June Noble, Christopher J. Kenyon, Carina Hibberd, Yuri Kotelevtsev, John J. Mullins, and Jonathan R. Seckl
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4716–4721. Published online 2001 March 27. doi: 10.1073/pnas.071562698.
PMCID: PMC31900
F-spondin is a contact-repellent molecule for embryonic motor neurons
Vered Tzarfati-Majar, Tal Burstyn-Cohen, and Avihu Klar
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4722–4727. Published online 2001 April 3. doi: 10.1073/pnas.081062398.
PMCID: PMC31901
Effect of nicotine on brain activation during performance of a working memory task
Monique Ernst, John A. Matochik, Stephen J. Heishman, John D. Van Horn, Peter H. Jons, Jack E. Henningfield, and Edythe D. London
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4728–4733. Published online 2001 March 27. doi: 10.1073/pnas.061369098.
PMCID: PMC31902
β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons
Qing-song Liu, Hideki Kawai, and Darwin K. Berg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4734–4739. Published online 2001 March 27. doi: 10.1073/pnas.081553598.
PMCID: PMC31903
Diacylglycerol kinase [var epsilon] regulates seizure susceptibility and long-term potentiation through arachidonoyl– inositol lipid signaling
Elena B. Rodriguez de Turco, Wen Tang, Matthew K. Topham, Fumio Sakane, Victor L. Marcheselli, Chu Chen, Akinobu Taketomi, Stephen M. Prescott, and Nicolas G. Bazan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4740–4745. Published online 2001 April 3. doi: 10.1073/pnas.081536298.
PMCID: PMC31904
Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
Yaron Hakak, John R. Walker, Cheng Li, Wing Hung Wong, Kenneth L. Davis, Joseph D. Buxbaum, Vahram Haroutunian, and Allen A. Fienberg
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4746–4751. doi: 10.1073/pnas.081071198.
PMCID: PMC31905
The generation, migration, and differentiation of olfactory neurons in the adult primate brain
David R. Kornack and Pasko Rakic
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4752–4757. doi: 10.1073/pnas.081074998.
PMCID: PMC31906
Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression
Arnaud Nicot and Emanuel DiCicco-Bloom
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4758–4763. doi: 10.1073/pnas.071465398.
PMCID: PMC31907
Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease
Jean-Michel Lecerf, Thomas L. Shirley, Quan Zhu, Aleksey Kazantsev, Peter Amersdorfer, David E. Housman, Anne Messer, and James S. Huston
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4764–4769. doi: 10.1073/pnas.071058398.
PMCID: PMC31908
Physiology
Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging
Teresa E. Seeman, Bruce S. McEwen, John W. Rowe, and Burton H. Singer
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4770–4775. Published online 2001 April 3. doi: 10.1073/pnas.081072698.
PMCID: PMC31909
Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation
Shumin Bian, Isabelle Favre, and Edward Moczydlowski
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4776–4781. Published online 2001 March 27. doi: 10.1073/pnas.081072398.
PMCID: PMC31910
Plant Biology
A postgermination developmental arrest checkpoint is mediated by abscisic acid and requires the ABI5 transcription factor in Arabidopsis
Luis Lopez-Molina, Sébastien Mongrand, and Nam-Hai Chua
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4782–4787. Published online 2001 April 3. doi: 10.1073/pnas.081594298.
PMCID: PMC31911
Jasmonic acid carboxyl methyltransferase: A key enzyme for jasmonate-regulated plant responses
Hak Soo Seo, Jong Tae Song, Jong-Joo Cheong, Yong-Hwan Lee, Yin-Won Lee, Ingyu Hwang, Jong Seob Lee, and Yang Do Choi
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4788–4793. Published online 2001 April 3. doi: 10.1073/pnas.081557298.
PMCID: PMC31912
A strategy for the identification of proteins targeted by thioredoxin
Hiroyuki Yano, Joshua H. Wong, Young Moo Lee, Myeong-Je Cho, and Bob B. Buchanan
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4794–4799. Published online 2001 March 27. doi: 10.1073/pnas.071041998.
PMCID: PMC31913
Psychology
Effects of temporal association on recognition memory
Guy Wallis and Heinrich H. Bülthoff
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4800–4804. Published online 2001 April 3. doi: 10.1073/pnas.071028598.
PMCID: PMC31914
Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory
Roberto Cabeza, Stephen M. Rao, Anthony D. Wagner, Andrew R. Mayer, and Daniel L. Schacter
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4805–4810. Published online 2001 April 3. doi: 10.1073/pnas.081082698.
PMCID: PMC31915
Social Sciences
Psychology
Effects of temporal association on recognition memory
Guy Wallis and Heinrich H. Bülthoff
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4800–4804. Published online 2001 April 3. doi: 10.1073/pnas.071028598.
PMCID: PMC31914
On a psychophysical transformed-rule up and down method converging on a 75% level of correct responses
Jozef J. Zwislocki and Evan M. Relkin
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4811–4814. Published online 2001 April 3. doi: 10.1073/pnas.081082598.
PMCID: PMC31916
Corrections
Correction
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. Published online 2001 April 3. doi: 10.1073/pnas.081082198.
PMCID: PMC55945
Corrects: Gunilla B. Toth, et al. Water-borne cues induce chemical defense in a marine alga (Ascophyllum nodosum). Proc Natl Acad Sci U S A. 2000 December 19; 97(26): 14418–14420.
Correction
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. Published online 2001 April 3. doi: 10.1073/pnas.091112698.
PMCID: PMC55946
Corrects: John D. Rummel. Special Feature: Planetary exploration in the time of astrobiology: Protecting against biological contamination. Proc Natl Acad Sci U S A. 2001 February 27; 98(5): 2128–2131.
Correction
Proc Natl Acad Sci U S A. 2001 April 10; 98(8): 4815. doi: 10.1073/pnas.091112798.
PMCID: PMC55947
Corrects: Pierre Colas, et al. Targeted modification and transportation of cellular proteins. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13720–13725.
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