Schedule
2008-2009 NIH Seminar Series: Advances in Public Health Genomics
In 2007, the NCI organized a highly successful monthly seminar series entitled, "Public Health Genomics: Closing the Gap Between Gene Discoveries and Population Health." Over nine months, 18 lectures by various expert speakers explored the topic of public health genomics, with a focus on cancer control and prevention. The lectures’ power point slides, reading materials and webcasts are all archived on the NCI website at: http://dceg.cancer.gov/news/meetings-events-upcoming/genomicscourse.
The 2007 series introduced NIH audiences and beyond to basic concepts of public health genomics. Nevertheless, there is a continued need for raising awareness, developing competencies and generating ideas for initiatives that can integrate genomics into population sciences to assess the role of genomics in practice and prevention. In addition, there are major ongoing genomics initiatives at NCI and other Institutes, as well as cross-cutting NIH Roadmap Initiatives related to genomics. All of these initiatives will lead to new knowledge and gene discoveries that could have lasting impact on healthcare and population health.
Nevertheless, the emerging scientific translation needs in the genomics era are substantial. Population sciences are now urgently needed to assess the distribution of genetic variants and their products, biomarkers and interactions with other genes and environmental factors. New methods are needed to assess the contribution of genes and gene-environment interactions (behavior, nutrition, chemicals and other exposures) to individual and population risks for various cancers. Behavioral and social sciences are needed to assess how genetic information can be used to affect behavior change to reduce the burden of cancer. Moreover, delivery research on clinical utility, effectiveness and economics of genomics-based health care applications are needed to assess their added value in cancer care and prevention. Genomics and related fields will also affect surveillance, dissemination and diffusion research as well as evaluation of cancer progression and survivorship. Without the expansion of population sciences in genomics, the promise of genome research and discoveries may not reach its full potential.
The 2008-2009 monthly one-hour seminar series entitled, "Advances in Public Health Genomics," will specifically explore ongoing, planned and future initiatives led by the NIH and other groups designed to accelerate the process for integrating advances in genomics and related fields into practice. A population approach will be emphasized and partnerships between basic sciences, medicine and public health will be highlighted.
Session 1: Introduction: The genomics translation highway presentation
Muin J. Khoury (CDC, NCI-DCCPS)
The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?
The NCI TRWG plan for early translational research presentation
Lynn M. Matrisian, PhD (Special Assistant to the Director, NCI)
NCI’s Translational Research Working Group (TRWG)’s webpage
TRWG Report-June 2007
Wednesday, September 24, 2008 1:00-2:30 EPN C-F
Session 2: Genomics in the GWAS era: What’s next for translation? presentation
Teri A. Manolio, MD, PhD
Director, Office of Population Genomics
Senior Advisor to the Director, NHGRI, for Population Genomics
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
Genetic mapping in human disease
Genomics in the (Cancer) GWAS era: What’s next for translation? presentation
Daniela Seminara, PhD, MPH
Epidemiology and Genetics Research Program, DCCPS, NCI
Wednesday, October 22, 2008 1:00-2:30 EPN H
Session 3: Challenges in the analysis of gene-environment interaction in the GWAS era
Exploiting Interactions for Enhanced Detection of Genetic and Environmental Risk-Factors for Complex Diseases presentation
Nilanjan Chatterjee, PhD
Biostatistics Branch, Division of Cancer Epidemiology and Genetics (DCEG), NCI
Studying Interactions between Environmental Exposures and Genetic Variants: Examples and Lessons Learned presentation
Nathaniel Rothman, MD, MPH, MHS
Occupational and Environmental Epidemiology Branch, DCEG, NCI
Wednesday, November 19, 2008 1:00-2:30 EPN H
Session 4: Can multiple genetic variants improve risk assessment and disease prevention?
Sholom Wacholder and Mitchell Gail (NCI-DCEG)
Wednesday, January 28, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
Session 5: Public health approach to pharmacogenomics: From discovery to translation
Andy Freedman (NCI-DCCPS) and Rochelle Long (NIGMS)
Wednesday, February 25, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
Session 6: Translation and health services research in the genomics era
Rebekah Rassoly (NIDDK) and Gurvaneet Randhawa (AHRQ)
Wednesday, March 25, 2009 1:00-2:30 EPN G
(30 minute PHGIG meeting to follow)
Session 7: Personal genome profiles: Science and policy issues
Kathy Hudson (Genetics and Public Policy Center) and Muin J. Khoury (CDC, NCI-DCCPS)
Wednesday, April 29, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
Session 8: What genomics decision support tools are needed for health practice?
Greg Feero (NHGRI), Mark Greene (NCI-DCEG)
Wednesday, May 27, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
Session 9: Obesity as a paradigm in public health genomics
Colleen Mc Bride (NHGRI) and Tanya Augurs-Collins (NCI-DCCPS)
Wednesday, June 24, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
Session 10: Epigenetics in disease control and prevention: When will it be ready for prime time?
Mukesh Verma (NCI-DCCPS)
Wednesday, August 26, 2009 1:00-2:30 EPN H
(30 minute PHGIG meeting to follow)
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