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Volume 2;  2005
Book Review
Review of "Systems Biology in Practice" by Edda Klipp, Ralf Hertwig, Axel Kowald, Christoph Wierling and Hans Lehrach
Paul S Agutter
Theor Biol Med Model. 2005; 2: 34. Published online 2005 August 26. doi: 10.1186/1742-4682-2-34.
PMCID: PMC1215524
Commentaries
The complexity of anatomical systems
Fabio Grizzi and Maurizio Chiriva-Internati
Theor Biol Med Model. 2005; 2: 26. Published online 2005 July 19. doi: 10.1186/1742-4682-2-26.
PMCID: PMC1180857
Uncertainty principle of genetic information in a living cell
Pierluigi Strippoli, Silvia Canaider, Francesco Noferini, Pietro D'Addabbo, Lorenza Vitale, Federica Facchin, Luca Lenzi, Raffaella Casadei, Paolo Carinci, Maria Zannotti, and Flavia Frabetti
Theor Biol Med Model. 2005; 2: 40. Published online 2005 September 30. doi: 10.1186/1742-4682-2-40.
PMCID: PMC1262781
Comment on and reply to "Analysis of variation of amplitudes in cell cycle gene expression" by Liu, Gaido and Wolfinger: On the analysis of gene expression during the normal, eukaryotic, cell cycle
Stephen Cooper
Theor Biol Med Model. 2005; 2: 47. Published online 2005 November 18. doi: 10.1186/1742-4682-2-47.
PMCID: PMC1298338
Editorial
A new journal – "Theoretical Biology and Medical Modelling"
Denys N Wheatley
Theor Biol Med Model. 2005; 2: 21. Published online 2005 June 12. doi: 10.1186/1742-4682-2-21.
PMCID: PMC1156957
Research
Human embryonal epithelial cells of the developing small intestinal crypts can express the Hodgkin-cell associated antigen Ki-1 (CD30) in spontaneous abortions during the first trimester of gestation
Demetrio Tamiolakis, John Venizelos, Maria Lambropoulou, Silva Nikolaidou, Sophia Bolioti, Maria Tsiapali, Dionysios Verettas, Panagiotis Tsikouras, Athanasios Chatzimichail, and Nikolas Papadopoulos
Theor Biol Med Model. 2005; 2: 1. Published online 2005 January 11. doi: 10.1186/1742-4682-2-1.
PMCID: PMC546234
Construction of predictive promoter models on the example of antibacterial response of human epithelial cells
Ekaterina Shelest and Edgar Wingender
Theor Biol Med Model. 2005; 2: 2. Published online 2005 January 12. doi: 10.1186/1742-4682-2-2.
PMCID: PMC546226
In vitro bioassay as a predictor of in vivo response
Ross Barnard and Konstantin G Gurevich
Theor Biol Med Model. 2005; 2: 3. Published online 2005 February 7. doi: 10.1186/1742-4682-2-3.
PMCID: PMC549212
Single cell studies of the cell cycle and some models
JM Mitchison
Theor Biol Med Model. 2005; 2: 4. Published online 2005 February 9. doi: 10.1186/1742-4682-2-4.
PMCID: PMC550673
Propagated repolarization of simulated action potentials in cardiac muscle and smooth muscle
Nicholas Sperelakis, Lakshminarayanan Ramasamy, and Bijoy Kalloor
Theor Biol Med Model. 2005; 2: 5. Published online 2005 February 14. doi: 10.1186/1742-4682-2-5.
PMCID: PMC550671
Volume-based non-continuum modeling of bone functional adaptation
Zhengyuan Wang and Adrian Mondry
Theor Biol Med Model. 2005; 2: 6. Published online 2005 February 28. doi: 10.1186/1742-4682-2-6.
PMCID: PMC553991
High-Temperature unfolding of a trp-Cage mini-protein: a molecular dynamics simulation study
Aswin Sai Narain Seshasayee
Theor Biol Med Model. 2005; 2: 7. Published online 2005 March 11. doi: 10.1186/1742-4682-2-7.
PMCID: PMC555740
The quantitation of buffering action I. A formal & general approach
Bernhard M Schmitt
Theor Biol Med Model. 2005; 2: 8. Published online 2005 March 15. doi: 10.1186/1742-4682-2-8.
PMCID: PMC1079953
The quantitation of buffering action II. Applications of the formal & general approach
Bernhard M Schmitt
Theor Biol Med Model. 2005; 2: 9. Published online 2005 March 16. doi: 10.1186/1742-4682-2-9.
PMCID: PMC1079954
The Estradiol-Dihydrotestosterone model of prostate cancer
A Edward Friedman
Theor Biol Med Model. 2005; 2: 10. Published online 2005 March 18. doi: 10.1186/1742-4682-2-10.
PMCID: PMC1079949
A topological model of biofeedback based on catecholamine interactions
Tapas K Basak, Suman Halder, Madona Kumar, Renu Sharma, and Bijoylaxmi Midya
Theor Biol Med Model. 2005; 2: 11. Published online 2005 March 21. doi: 10.1186/1742-4682-2-11.
PMCID: PMC1079950
Tyrosine phosphorylation of myosin heavy chain during skeletal muscle differentiation: an integrated bioinformatics approach
DF Harney, RK Butler, and RJ Edwards
Theor Biol Med Model. 2005; 2: 12. Published online 2005 March 25. doi: 10.1186/1742-4682-2-12.
PMCID: PMC1079951
Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction
Rovshan M Ismailov
Theor Biol Med Model. 2005; 2: 13. Published online 2005 March 30. doi: 10.1186/1742-4682-2-13.
PMCID: PMC1079952
Hyperbolastic growth models: theory and application
Mohammad Tabatabai, David Keith Williams, and Zoran Bursac
Theor Biol Med Model. 2005; 2: 14. Published online 2005 March 30. doi: 10.1186/1742-4682-2-14.
PMCID: PMC1084364
Location of DNA damage by charge exchanging repair enzymes: effects of cooperativity on location time
Kasper Astrup Eriksen
Theor Biol Med Model. 2005; 2: 15. Published online 2005 April 8. doi: 10.1186/1742-4682-2-15.
PMCID: PMC1142343
Breakdown of accommodation in nerve: a possible role for persistent sodium current
Kristian Hennings, Lars Arendt-Nielsen, and Ole K Andersen
Theor Biol Med Model. 2005; 2: 16. Published online 2005 April 12. doi: 10.1186/1742-4682-2-16.
PMCID: PMC1090618
An ETP model (exclusion-tolerance-progression) for multi drug resistance
Subburaj Kannan
Theor Biol Med Model. 2005; 2: 17. Published online 2005 April 27. doi: 10.1186/1742-4682-2-17.
PMCID: PMC1131929
Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition
Yoichi Nakayama, Ayako Kinoshita, and Masaru Tomita
Theor Biol Med Model. 2005; 2: 18. Published online 2005 May 9. doi: 10.1186/1742-4682-2-18.
PMCID: PMC1142344
Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs
Vivek K Mutalik and KV Venkatesh
Theor Biol Med Model. 2005; 2: 19. Published online 2005 May 20. doi: 10.1186/1742-4682-2-19.
PMCID: PMC1180476
Promoter addresses: revelations from oligonucleotide profiling applied to the Escherichia coli genome
Karthikeyan Sivaraman, Aswin Sai Narain Seshasayee, Krishnakumar Swaminathan, Geetha Muthukumaran, and Gautam Pennathur
Theor Biol Med Model. 2005; 2: 20. Published online 2005 May 31. doi: 10.1186/1742-4682-2-20.
PMCID: PMC1166578
The ups and downs of biological timers
Noa Rappaport, Shay Winter, and Naama Barkai
Theor Biol Med Model. 2005; 2: 22. Published online 2005 June 20. doi: 10.1186/1742-4682-2-22.
PMCID: PMC1208956
Predicting transcription factor activities from combined analysis of microarray and ChIP data: a partial least squares approach
Anne-Laure Boulesteix and Korbinian Strimmer
Theor Biol Med Model. 2005; 2: 23. Published online 2005 June 24. doi: 10.1186/1742-4682-2-23.
PMCID: PMC1182396
Identification and isolation of embryonic stem cells in reproductive endocrinology: theoretical protocols for conservation of human embryos derived from in vitro fertilization
Eric Scott Sills, Takumi Takeuchi, Noriko Tanaka, Queenie V Neri, and Gianpiero D Palermo
Theor Biol Med Model. 2005; 2: 25. Published online 2005 July 18. doi: 10.1186/1742-4682-2-25.
PMCID: PMC1185568
Statistical distribution of blood serotonin as a predictor of early autistic brain abnormalities
Skirmantas Janušonis
Theor Biol Med Model. 2005; 2: 27. Published online 2005 July 19. doi: 10.1186/1742-4682-2-27.
PMCID: PMC1199627
Modelling of oedemous limbs and venous ulcers using partial differential equations
Hassan Ugail and Michael J Wilson
Theor Biol Med Model. 2005; 2: 28. Published online 2005 August 3. doi: 10.1186/1742-4682-2-28.
PMCID: PMC1198260
The fractal geometry of nutrient exchange surfaces does not provide an explanation for 3/4-power metabolic scaling
Page R Painter
Theor Biol Med Model. 2005; 2: 30. Published online 2005 August 11. doi: 10.1186/1742-4682-2-30.
PMCID: PMC1226149
Allometric scaling of the maximum metabolic rate of mammals: oxygen transport from the lungs to the heart is a limiting step
Page R Painter
Theor Biol Med Model. 2005; 2: 31. Published online 2005 August 11. doi: 10.1186/1742-4682-2-31.
PMCID: PMC1236962
On the number of founding germ cells in humans
Chang-Jiang Zheng, E Georg Luebeck, Breck Byers, and Suresh H Moolgavkar
Theor Biol Med Model. 2005; 2: 32. Published online 2005 August 24. doi: 10.1186/1742-4682-2-32.
PMCID: PMC1215522
Possible Cis-acting signal that could be involved in the localization of different mRNAs in neuronal axons
Gonzalo E Aranda-Abreu, Ma Elena Hernández, Abraham Soto, and Jorge Manzo
Theor Biol Med Model. 2005; 2: 33. Published online 2005 August 24. doi: 10.1186/1742-4682-2-33.
PMCID: PMC1215523
Nucleic acid chaperons: a theory of an RNA-assisted protein folding
Jan C Biro
Theor Biol Med Model. 2005; 2: 35. Published online 2005 September 1. doi: 10.1186/1742-4682-2-35.
PMCID: PMC1232867
Boundary effects influence velocity of transverse propagation of simulated cardiac action potentials
Nicholas Sperelakis, Bijoy Kalloor, and Lakshminarayanan Ramasamy
Theor Biol Med Model. 2005; 2: 36. Published online 2005 September 6. doi: 10.1186/1742-4682-2-36.
PMCID: PMC1236963
A comparative study of a theoretical neural net model with MEG data from epileptic patients and normal individuals
A Kotini, P Anninos, AN Anastasiadis, and D Tamiolakis
Theor Biol Med Model. 2005; 2: 37. Published online 2005 September 7. doi: 10.1186/1742-4682-2-37.
PMCID: PMC1236964
Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer
L Michel Espinoza-Fonseca
Theor Biol Med Model. 2005; 2: 38. Published online 2005 September 20. doi: 10.1186/1742-4682-2-38.
PMCID: PMC1243243
Volume of the effect compartment in simulations of neuromuscular block
Vladimir Nigrovic, Johannes H Proost, Anton Amann, and Shashi B Bhatt
Theor Biol Med Model. 2005; 2: 41. Published online 2005 October 3. doi: 10.1186/1742-4682-2-41.
PMCID: PMC1262782
Hybrid dynamic/static method for large-scale simulation of metabolism
Katsuyuki Yugi, Yoichi Nakayama, Ayako Kinoshita, and Masaru Tomita
Theor Biol Med Model. 2005; 2: 42. Published online 2005 October 4. doi: 10.1186/1742-4682-2-42.
PMCID: PMC1262783
Modeling the signaling endosome hypothesis: Why a drive to the nucleus is better than a (random) walk
Charles L Howe
Theor Biol Med Model. 2005; 2: 43. Published online 2005 October 19. doi: 10.1186/1742-4682-2-43.
PMCID: PMC1276819
A mathematical model of the euglycemic hyperinsulinemic clamp
Umberto Picchini, Andrea De Gaetano, Simona Panunzi, Susanne Ditlevsen, and Geltrude Mingrone
Theor Biol Med Model. 2005; 2: 44. Published online 2005 November 3. doi: 10.1186/1742-4682-2-44.
PMCID: PMC1291408
Supply-demand balance in outward-directed networks and Kleiber's law
Page R Painter
Theor Biol Med Model. 2005; 2: 45. Published online 2005 November 10. doi: 10.1186/1742-4682-2-45.
PMCID: PMC1325050
Analysis of variation of amplitudes in cell cycle gene expression
Delong Liu, Kevin W Gaido, and Russ Wolfinger
Theor Biol Med Model. 2005; 2: 46. Published online 2005 November 11. doi: 10.1186/1742-4682-2-46.
PMCID: PMC1315354
Repolarization of the action potential enabled by Na+ channel deactivation in PSpice simulation of cardiac muscle propagation
Lakshminarayanan Ramasamy and Nicholas Sperelakis
Theor Biol Med Model. 2005; 2: 48. Published online 2005 December 12. doi: 10.1186/1742-4682-2-48.
PMCID: PMC1326226
A Global Workspace perspective on mental disorders
Rodrick Wallace
Theor Biol Med Model. 2005; 2: 49. Published online 2005 December 21. doi: 10.1186/1742-4682-2-49.
PMCID: PMC1343591
Reviews
Vasculature deprivation – induced osteonecrosis of the rat femoral head as a model for therapeutic trials
Jacob Bejar, Eli Peled, and Jochanan H Boss
Theor Biol Med Model. 2005; 2: 24. Published online 2005 July 5. doi: 10.1186/1742-4682-2-24.
PMCID: PMC1208957
Three subsets of sequence complexity and their relevance to biopolymeric information
David L Abel and Jack T Trevors
Theor Biol Med Model. 2005; 2: 29. Published online 2005 August 11. doi: 10.1186/1742-4682-2-29.
PMCID: PMC1208958
Data from necropsy studies and in vitro tissue studies lead to a model for allometric scaling of basal metabolic rate
Page R Painter
Theor Biol Med Model. 2005; 2: 39. Published online 2005 September 27. doi: 10.1186/1742-4682-2-39.
PMCID: PMC1262780
Neurogenetic interactions and aberrant behavioral co-morbidity of attention deficit hyperactivity disorder (ADHD): dispelling myths
David E Comings, Thomas JH Chen, Kenneth Blum, Julie F Mengucci, Seth H Blum, and Brian Meshkin
Theor Biol Med Model. 2005; 2: 50. Published online 2005 December 23. doi: 10.1186/1742-4682-2-50.
PMCID: PMC1352384
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