MLSCN Centers
The MLSCN Pilot Phase ended in June 2008.
Assays may now be submitted to the Molecular Libraries Probe Production Network.
Please see: Access to MLPCN Screening, in the MLPCN section of the website, for more information on submitting an assay to the MLPCN.
Since the MLPCN Screening Centers will vary from those in the pilot phase, please be sure to look at the MLPCN Centers Information (when it becomes available) for more information on screening center capabilities.
The Molecular Libraries Screening Centers Network (MLSCN) consists of 10 centers with a diverse set of screening platform technologies that include ultraHTS, cell based imaging, and flow cytometry. The network is capable of implementing many assay formats including cell-based, biochemical, protein-protein interactions and some model organisms. At this time, whole organism assay capability is being developed within the network and is currently available to a limited extent and only at very low throughput. The network can implement biological assays using a variety of detection systems that include: luminescence, fluorescence, FLIPR, FRET, SPA, absorbance, ELISA, microscopy-based imaging, and small molecule microarray.
MLSCN Centers
| PI Name | Institution Name | Title |
|---|---|---|
| Austin, Chris | NHGRI | NIH Chemical Genomics Center (NCGC) Center Website Center Summary Page |
| Diamond, Scott | University Of Pennsylvania | The Penn Center for Molecular Discovery Center Website Abstract (from CRISP) Center Summary Page |
| Dingledine, Raymond | Emory University | Emory Chemistry-Biology Center in the MLSCN Abstract (from CRISP) Center Summary Page |
| Lazo, John | University Of Pittsburgh At Pittsburgh | University of Pittsburgh Molecular Libraries Screening Center Center Website Abstract (from CRISP) Center Summary Page |
| Piazza, Gary | Southern Research Institute | Southern Research Molecular Libraries Screening Center Abstract (from CRISP) Center Summary Page |
| Reed, John | The Burnham Institute | San Diego Center for Chemical Genomics Abstract (from CRISP) Center Summary Page |
| Rosen, Hugh | The Scripps Research Institute | Scripps Research Institute Molecular Screening Center Abstract (from CRISP) Center Summary Page |
| Rothman, James | Columbia University Medical Center | MLSCN Center at Columbia University Abstract (from CRISP) Center Summary Page |
| Sklar, Larry | University Of New Mexico Albuquerque | New Mexico Molecular Libraries Screening Center Center Website Abstract (from CRISP) Center Summary Page |
| Weaver, C. David | Vanderbilt University | Vanderbilt Screening Center for GPCRs, Ion Channels, and Transporters Center Website Abstract (from CRISP) Center Summary Page |
MLSCN Capabilities
A brief summary of each of the Center’s capabilities can be found below.
