NIH Resources
The links below represent resources for investigators who wish to use MLSCN output as a starting point for the development of clinical candidates.
NIH
- Public private partnerships: http://www.ippph.org
- US-Japan Brain Research Cooperative Program (BRCP)
- National Technology Centers for Networks and Pathways (TCNP)
- NIH RAID program (Rapid Access to Interventional Development)
- Send queries to: NIH-RAID@niddk.nih.gov
NIAID
- Development of Novel Interventions and Tools for the Control of Malaria, Neglected Tropical Diseases and their Vectors (R01)
- Resource Guide for the Development of AIDS Therapies
- In Vitro and Animal Models for Emerging Infectious Diseases and Biodefense
- In Vitro and Antiviral Screening Program
- RFP for support of preclinical services for pathogens of potential BioD concern
- NIH DAIDS Research
- DAIDS resources that could possibly be used for further probe/drug lead follow-up can be found at http://www3.niaid.nih.gov/research/resources/default.htm
- NIH AIDS Research and Reference Reagent Program: This program provides various reagents and probes; could be a vehicle for making new reagents/probes available to the research community
- Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF): The TAACF Web site describes compound evaluation in various in vitro and in vivo models.
- Drug Formulation and Manufacture: This resource can provide scale up synthesis and drug formulation development and production.
- Drug Resynthesis: This resource provides for scale up synthesis of compounds.
- Resource Guide for the Development of AIDS Therapies: This site describes the preclinical resources that cover the HIV and opportunistic infectious agents resources available to support most of the needed preclinical studies on novel compounds. The list of capabilities is as follows:
- Drug Discovery / Basic Research
- Animal Efficacy
- Pharmacokinetics and Toxicology
- Chemistry, Formulation, and ManufacturingAntiviral (non-HIV) Therapeutics
- Databases
- HIV Therapeutics
- Immunologic Evaluations
- Opportunistic Infection Therapeutics
- SIV and SHIV Evaluations
- TB Therapeutics
- Topical Microbicides
NCI
- Development of Clinical Imaging Drugs & Enhancers (DCIDE)
- Human tumor cell line screen
- Rapid Access to NCI Discovery Resources (R*A*N*D)
- Rapid Access to Intervention Development (RAID)
- Drug Development Group (DDG)
NIDDK
- Type 1 Diabetes (T1D) Special Statutory Funding Program - Pre-clinical development of therapeutic agents
- Type 1 diabetes mellitus RAID program: See also,http://www.niaid.nih.gov/daids/pdatguide/topmic.htm
- Animal Models of Diabetic Complications Consortium (NIDDK)
- Mouse metabolic phenotyping centers (NIDDK)
NINDS
- Anticonvulsant Screening Program
- NINDS Translational Research Opportunities
- Counterterrorism Research: See also, http://www.ninds.nih.gov/funding/research/counterterrorism/index.htm
