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Technologies Available for Licensing from NIH/FDA
Rotavirus
| Multivalent Human-Bovine Rotavirus Vaccine |
This invention describes multivalent immunogenic compositions comprising at least four (4) human-bovine reassortant rotaviruses, where the gene encoding VP7 protein of G1, G2, G3, or G4 human rotavirus strain is inserted into a bovine rotavirus backbone. These VP7 serotypes represent the clinically most important human rotavirus serotypes, which depends on VP4 and VP7 proteins, both found in the viral capsid and both of which independently induc... More ...
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| Attenuated Human Rotavirus Vaccine
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Rotaviruses are recognized as the single most important etiologic agent of severe diarrhea in both developed and nondeveloped countries. This invention embodies an attenuated rotavirus as a vaccine. The claims of the invention relate to the generation of a cold-adapted virus that is not efficient in replication at normal human body temperatures and therefore may be capable of stimulating an immune response without causing illness. In a limited... More ...
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Technologies Available for Licensing from Non-Profit Institutions
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