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Announcement Date Announcement Comment or Action Deadline
2008
November 24, 2008 Availability of the ICCVAM Test Method Evaluation Report: Validation Status of Five In Vitro Test Methods Proposed for Assessing Potential Pyrogenicity of Pharmaceuticals and Other Products and Final Background Review Document: Validation Status of Five In Vitro Test Methods Proposed for Assessing Potential Pyrogenicity of Pharmaceuticals and Other Products; Notice of Transmittal of ICCVAM Test Method Recommendations to Federal Agencies -
October 16, 2008 ICCVAM 2006-2007 Biennial Report now available -
September 4, 2008 Acceptance of ICCVAM-Recommended Ocular Safety Methods Featured in Journal Environmental Health Perspectives -
August 25, 2008 ICCVAM Preparation of OECD Test Guidelines for In Vitro Ocular Test Methods -
June 23, 2008 Press Release: Newly Approved Ocular Safety Methods Reduce Animal Testing -
June 15, 2008 Update on U.S. regulatory acceptance of alternative methods -
May 20, 2008 Independent Scientific Peer Review Panel Report on the Murine Local Lymph Node Assay now available July 7, 2008
Apr. 7, 2008 Non-Animal Assessment Approach for Evaluating Eye Irritation Potential for Anti-Microbial Cleaning Products: Request for Nominations for an Independent Expert Panel and Submission of Relevant Data May 19, 2008
Apr. 2, 2008 View NICEATM-ICCVAM Posters presented at the 2008 Society of Toxicology Meeting -
March 25, 2008 ICCVAM Recommendations on Use of In Vitro Cytotoxicity Assays for Estimating Acute Systemic Toxicity -
Mar. 18, 2008 Materials from the February 2008 Scientific Workshop on Acute Chemical Safety Testing now available -
Feb. 29, 2008 ICCVAM Recommendations on Use of In Vitro Cytotoxicity Assays for Estimating Acute Systemic Toxicity -
Feb. 5, 2008 Availability of the NICEATM-ICCVAM Five-Year Plan -
Jan. 8, 2008 Independent Scientific Peer Review Panel Meeting on the Murine Local Lymph Node Assay; Availability of Draft Background Review Documents; Request for Comments Registration: February 20, 2008
Comments: February 22, 2008
2007
Dec. 6, 2007 Workshop on Acute Chemical Testing Registration: January 22, 2008
Nov. 26, 2007 ICCVAM Releases Test Method Evaluation Report and final Background Review Documents (BRDs) on In Vitro Ocular Test Methods for Identifying Corrosives and Severe Irritants; Recommendations Transmitted to Federal Agencies -
Nov 15, 2007 ICCVAM Tenth Anniversary Symposium Registration: January 25, 2008
Oct 25, 2007 ICCVAM Recommendations on In Vitro Test Methods for Detecting Ocular Corrosives and Severe Irritants -
Sep 12, 2007 Draft Performance Standards for the Murine Local Lymph Node Assay: Request for Comments Comment: Oct 29, 2007
Aug 16, 2007 View NICEATM/ICCVAM Presentations at the Sixth World Congress on Alternatives and Animal Use in the Life Sciences -
June 7, 2007 Request for Ocular Irritancy Test Data From Human, Rabbit, and In Vitro Studies Using Standardized Testing Methods Data Submission: July 23, 2007
May 17, 2007 The Murine Local Lymph Node Assay: Request for Comments, Nominations of Scientific Experts, and Submission of Data Data Submission, Comments and Nominations: June 15, 2007
May 9, 2007 Request for Data on the Use of Topical Anesthetics and Systemic Analgesics for In Vivo Eye Irritation Testing Data Submission: June 25, 2007
May 9, 2007 Submit Public Comments on the Independent Peer Review Panel Report: Five In Vitro Test Methods Proposed for Assessing Potential Pyrogenicity of Pharmaceuticals and Other Products Comment: June 25, 2007
May 7, 2007 Availability of the Draft NICEATM-ICCVAM Five-Year Plan Comment: June 7, 2007
May 2, 2007 Availability of the Independent Peer Review Panel Report: Five In Vitro Test Methods Proposed for Assessing Potential Pyrogenicity of Pharmaceuticals and Other Products -
Apr. 6, 2007 Town Meeting to Receive Public Comment on the Draft NICEATM-ICCVAM Five-Year Plan Registration: June 7, 2007

Comment: June 7, 2007
2006
Dec. 11, 2006 Announcement of an Independent Scientific Peer Review Meeting on the Use of In Vitro Pyrogenicity Testing Methods; Request for Comments
Registration: Jan. 23, 2007

Comment: Jan. 26, 2007
Nov. 30, 2006 ICCVAM Releases Test Method Evaluation Report and Background Review Document (BRD) on In Vitro Cytotoxicity Test Methods for Estimating Acute Oral Systemic Toxicity -
Nov. 17, 2006 ICCVAM releases Biennial Progress Report -
Nov. 13, 2006 Request for Public Comments on
The Development of a 5-Year Plan to Research, Develop, Translate, and Validate New and Revised Non-animal and Other Alternative Assays for Integration of Relevant and Reliable Methods into Federal Agency Testing Programs
Comment: Dec. 31, 2006
Nov. 1, 2006 Availability of the Pre-Publication Release:
ICCVAM Test Method Evaluation Report: In Vitro Cytotoxicity Test Method for Estimating Starting Doses for Acute Oral Systemic Toxicity
and the
In Vitro Acute Toxicity Test Methods Background Review Document (BRD)

For consideration at the November 30, 2006, meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM)
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Nov. 16, 2006 Availability of the Biennial Progress Report:
Interagency Coordinating Committee on the Validation of Alternative Methods
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Oct. 16, 2006 Availability of the NICEATM Pre-Screen Evaluation of the In Vitro Endocrine Disruptor Assay (Robotic MCF-7 Cell Proliferation Assay of Estrogenic Activity); Request for Comments and Nominations of Other In Vitro Endocrine Disruptor Test Methods Nov. 30, 2006
Sept. 28, 2006 Availability of the Finalized Addendum To Report:
ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential Endocrine Disruptors: Estrogen Receptor and Androgen Receptor Binding and Transcriptional Activation Assays (NIH Publication No. 03-4503, May 2003)
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Oct. 25, 2006 Availability of the Current Status of In Vitro Test Methods for Detecting Ocular Corrosives and Severe Irritants:

View ICCVAM Ocular Test Method Evaluation Report
and Background Review Documents (BRDs)

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July 11, 2006 Availability of the Peer Review Panel Report: The Use of In Vitro Basal Cytotoxicity Test Methods for Estimating Starting Doses for Acute Oral Systemic Toxicity Testing Aug. 25, 2006

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