Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsored by: |
Northwestern University |
---|---|
Information provided by: | Northwestern University |
ClinicalTrials.gov Identifier: | NCT00787176 |
Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at Prentice Women's Hospital. Optimizing the variables which could affect fetal heart rate patterns at the time of initiation of analgesia, such as fluid administration and oxytocin management, could help us provide better care for our patients and their fetuses.
Hypotheses: Patients who receive a 1000 mL fluid bolus and lower rates of oxytocin administration will have fewer non-reassuring FHR changes.
Condition | Intervention |
---|---|
Pregnancy Labor |
Drug: lactated ringers solution and normal oxytocin dose Drug: 1000 mL bolus Half-dose oxytocin Drug: No bolus of lactated ringers solution and routine oxytocin Drug: No bolus of lactated ringers solution and a half-dose oxytocin |
Study Type: | Interventional |
Study Design: | Prevention, Randomized, Single Blind (Subject), Dose Comparison, Parallel Assignment, Safety/Efficacy Study |
Official Title: | The Association Between Fluid Administration,Oxytocin Administration, and Fetal Heart Rate Changes |
Estimated Enrollment: | 352 |
Study Start Date: | September 2007 |
Estimated Study Completion Date: | September 2009 |
Arms | Assigned Interventions |
---|---|
1: Experimental
A 1000 mL bolus Routine oxytocin
|
Drug: lactated ringers solution and normal oxytocin dose
lactated ringers solution and normal oxytocin dose
|
2: Experimental
1000 mL bolus Half-dose oxytocin
|
Drug: 1000 mL bolus Half-dose oxytocin
1000 mL bolus Half-dose oxytocin
|
3: Experimental
No bolus of lactated ringers solution and routine oxytocin
|
Drug: No bolus of lactated ringers solution and routine oxytocin
No bolus of lactated ringers Routine oxytocin
|
4: Experimental
No bolus Half-dose oxytocin
|
Drug: No bolus of lactated ringers solution and a half-dose oxytocin
No bolus of lactated ringers solution and a half-dose oxytocin
|
Ages Eligible for Study: | 18 Years to 60 Years |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Cynthia A Wong, M.D. | 321-472-3590 | c-wong2@Northwestern.edu |
Contact: Robert McCarthy, PharmD |
United States, Illinois | |
Prentice WOmen's Hospital | Recruiting |
Chicago, Illinois, United States, 60611 |
Responsible Party: | NOrthwestern University ( Cynthia A. WOng, M.D. ) |
Study ID Numbers: | 0524-034 |
Study First Received: | November 6, 2008 |
Last Updated: | November 6, 2008 |
ClinicalTrials.gov Identifier: | NCT00787176 |
Health Authority: | United States: Institutional Review Board |
Oxytocin Term Singleton Labor, Obstetric |
Oxytocin |
Oxytocics Therapeutic Uses Physiological Effects of Drugs Reproductive Control Agents Pharmacologic Actions |