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Sponsored by: |
University of California, San Francisco |
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Information provided by: | University of California, San Francisco |
ClinicalTrials.gov Identifier: | NCT00187733 |
The current study is part of a large multi-investigator grant to look at the pharmacogenetics of a number of membrane transporters. Previously, the investigators have recruited a cohort of healthy volunteers (Studies of Pharmacogenetics in Ethnically-Diverse Populations, or SOPHIE) and have resequenced the coding region of a number of membrane transporter genes to identify genetic polymorphisms in these genes. Subjects in this cohort have agreed to be called back for recruitment in further studies based on their own genetic sequence, allowing the investigators the possibility to prospectively study the influence of genetic polymorphisms on particular phenotypes (i.e., genotype-to-phenotype studies). The investigators plan to take a genotype-to-phenotype approach to study the influence of specific polymorphisms in the novel organic cation transporter 2 (OCTN2) gene on carnitine and lipid metabolism in healthy subjects.
Condition |
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Healthy |
Study Type: | Observational |
Study Design: | Natural History, Cross-Sectional, Defined Population, Prospective Study |
Ages Eligible for Study: | 18 Years to 45 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Tom Urban, PharmD | 415-476-6756 | urbant@pharmacy.ucsf.edu |
United States, California | |
San Francisco General Hospital | Recruiting |
San Francisco, California, United States, 94143 | |
Contact: Tom Urban, PharmD 415-476-6756 urbant@pharmacy.ucsf.edu |
Principal Investigator: | Kathleen Giacomini, PhD | University of California, San Francisco |
Study ID Numbers: | 1005 |
Study First Received: | September 14, 2005 |
Last Updated: | September 24, 2007 |
ClinicalTrials.gov Identifier: | NCT00187733 |
Health Authority: | United States: Institutional Review Board |
healthy volunteer |
Healthy Carnitine |