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Porphyrins - urine

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Contents of this page:

Illustrations

Female urinary tract
Female urinary tract
Male urinary tract
Male urinary tract
Porphyrin urine test
Porphyrin urine test

Alternative Names    Return to top

Uroporphyrin

Definition    Return to top

Porphyrins help form many important substances in the body including hemoglobin, a part of red blood cells that carries oxygen in the blood.

Porphyrins can be found in urine. A urine porphyrins test can be done to tell how many porphyrins you have in your urine.

How the Test is Performed    Return to top

A 24-hour urine sample is needed.

In infants:

Thoroughly wash the area around the urethra (the area where urine exits). Open the urine collection bag provided by your doctor. For boys, place the entire penis in the bag and attach it to the surrounding skin. For girls, place the bag over the labia.

You can diaper the baby as usual, over the collection bag.

Note: It may take a few tries to get the bag correctly into place. Check the infant frequently and change the bag after the infant has urinated. Drain the urine into the special container provided by your health care provider. Take the container to the laboratory or your health care provider as soon as possible.

How to Prepare for the Test    Return to top

Extra collection bags may be necessary if the urine sample is being taken from an infant.

Your doctor may tell you to stop taking any medicines that may affect the test results. NEVER stop taking any medicine without first talking to your doctor.

Drugs that can affect test measurements include:

How the Test Will Feel    Return to top

The test will feel the same as normal urination.

Why the Test is Performed    Return to top

Your doctor will order this test if you have signs of porphyria or other disorders that can cause abnormal urine porphyrins.

Normal Results    Return to top

Normal results vary. In general, for a 24-hour urine test, the range is about 50 - 300 mg (milligrams).

What Abnormal Results Mean    Return to top

Abnormal results may be due to:

References    Return to top

Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingston; 2005:505.

McPherson RA and Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. Philadelphia, Pa: WB Saunders; 2007:408-9.

Update Date: 3/8/2007

Updated by: Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network.

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