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Lead poisoning

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Alternative Names   

Plumbism

Definition    Return to top

Lead is a very strong poison. When a person swallows a lead object or inhales lead dust, some of the poison can stay in the body and cause serious health problems. A single high, toxic dose of lead can cause severe emergency symptoms. However, it is more common for lead poisoning to build up slowly over time. This occurs from repeated exposure to small amounts of lead. In this case, there may not be any obvious symptoms, but the lead can still cause serious health problems over time, such as difficulty sleeping or lowered IQ in children.

Lead is much more harmful to children than adults because it can affect children's developing nerves and brains. The younger the child, the more harmful lead can be. Unborn children are the most vulnerable.

Children get lead in their bodies when they put lead objects in their mouths, especially if they swallow the lead object. They can even get lead poison on their fingers from touching a dusty or peeling lead object, and then putting their fingers in their mouths or eating food afterward. Tiny amounts of lead can also be inhaled.

Testing shows that many children have too much lead in their blood. Overall, about 1 in 20 preschoolers have high levels of lead in their blood. Any child can be affected. Children living in cities or older houses are more likely to have high levels.

Where Found    Return to top

Lead used to be very common in gasoline and house paint in the U.S. Although these items are no longer made with lead in them, lead is still a health problem. Lead is everywhere, including dirt, dust, new toys, and old house paint. Unfortunately, you can't see, taste, or smell lead.

Lead is found in:

Symptoms    Return to top

There are many possible symptoms of lead poisoning. Lead can affect many different parts of the body. Over time, even low levels of lead exposure can harm a child's mental development. The possible health problems get worse as the level of lead in the blood gets higher. Possible complications include:

The symptoms of lead poisoning may include:

Home Care    Return to top

You can reduce your exposure to lead. Consider the following steps:

Another excellent source of information is the National Lead Information Center at (800) 424-5323.

Before Calling Emergency    Return to top

Try to identify the following information:

Poison Control    Return to top

If someone has severe symptoms from possible lead exposure, such as vomiting or seizures, call 911 immediately.

For other symptoms that you think may be caused by lead poisoning, call your local poison control center.

The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the U.S. use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

What to Expect at the Emergency Room    Return to top

Except in severe cases where someone has received a high toxic dose, a trip to the emergency room is not necessary. Contact your health care provider or department of public health if you suspect possible low-level lead exposure. A blood lead test can help identify whether a problem exists. Over 10 micrograms per deciliter is a concern. In many states, blood screening is recommended for young children at risk. 

Other lab tests may include:

For children whose blood levels are at a moderately concerning level, the steps are to identify all major sources of lead exposure and keep the child away from it. Follow-up blood testing may be needed.

Chelation therapy is a procedure that can remove higher levels of lead that have built up in a person's body over time.

In cases where someone has potentially eaten a high toxic dose of lead in a short period of time, the following treatments might be done:

Outlook (Prognosis)    Return to top

Adults who have had mildly elevated lead levels often recover without problems. In children, even mild lead poisoning can have a permanent impact on attention and IQ.

People with higher lead levels have a greater risk of long-lasting health problems, and must be followed carefully. Their nerves and muscles can be greatly affected and may no longer function as well as they should. Other body systems may be harmed to various degrees, such as the kidneys and blood vessels. People who survive toxic lead levels may suffer some permanent brain damage. Children are more vulnerable to serious long-term problems.

A complete recovery from chronic lead poisoning may take months to years. Symptoms resembling chronic intoxication may be develop over a period weeks or months.

References    Return to top

Bleecker ML, et al. Differential effects of lead exposure on components of verbal memory. Occup Environ Med. 2005 Mar;62(3):181-7.

Chen A, Dietrick, KN, Ware, JH, et al.  IQ and Blood Lead from 2 to 7 Years of Age: Are the Effects in Older Children the Residual of High Blood Lead Concentrations in 2-Year-Olds? Environ Health Perspect. 2005 May;113(5):597-601.

Tong S, et al. Environmental Lead Exposure: A Public Health Problem of Global Dimensions. Bull World Health Organ. 2000; 78(9): 1068-77.

Wright RO, et al. Association between iron deficiency and blood lead level in a longitudinal analysis of children followed in an urban primary care clinic. J Pediatr. 2003;142: 9–14.

Update Date: 4/19/2007

Updated by: Eric Perez, MD, Department of Emergency Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network.

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