How Can Thrombotic Thrombocytopenic Purpura Be Prevented?

Both inherited and acquired thrombotic thrombocytopenic purpura (TTP) appear suddenly with no clear cause. You can’t prevent either type.

If you’ve had TTP, it’s important to watch for signs and symptoms of a relapse (flareup). (See "Living With Thrombotic Thrombocytopenic Purpura” for more information.)

You also should talk to your doctor about factors that may trigger TTP or a flareup, including:

• Diseases or conditions you may have, such as pregnancy, cancer, HIV, infection, or lupus.
• Any prior medical procedures, such as a bone marrow transplant.
• Medicines you may take, such as ticlopidine, clopidogrel, cyclosporine A, chemotherapy, and hormone replacement therapy and estrogens. Your doctor may change some of these medicines.