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Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
November 8, 2007
Volume 19, No. 19

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Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Analysing two dinucleotide repeats of FVIII gene in Iranian population
Rabbani B, et al.
Haemophilia 2007 Nov;13(6):740-4

Genetic polymorphism of CYP2C19 in Maharashtrian population
Ghodke Y, et al.
Eur J Epidemiol 2007 Nov

 

Infectious and Parasitic Diseases

Association of TNF-alpha -308 polymorphism with the outcome of hepatitis B virus  infection in Turkey
Basturk B, et al.
Infect Genet Evol 2007 Sep

 

Neoplasms

Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma
Katkoori VR, et al.
Front Biosci 2008;13:1050-61

BRCA1 and BRCA2 germline mutation analysis in the Indonesian population
Purnomosari D, et al.
Breast Cancer Res Treat 2007 Dec;106(2):297-304

Analysis of CXCL12 3'UTR G>A polymorphism in colorectal cancer
Hidalgo-Pascual M, et al.
Oncol Rep 2007 Dec;18(6):1583-7

Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII
Vairaktaris E, et al.
Oncol Rep 2007 Dec;18(6):1537-43

p53 pathway gene single nucleotide polymorphisms and chronic lymphocytic leukemia
Lahiri O, et al.
Cancer Genet Cytogenet 2007 Nov;179(1):36-44

Variants in circadian genes and prostate cancer risk: a population-based study in China
Chu LW, et al.
Prostate Cancer Prostatic Dis 2007 Nov

Polymorphisms in genes related to activation or detoxification of carcinogens might interact with smoking to increase renal cancer risk: results from The Netherlands Cohort Study on diet and cancer
Smits KM, et al.
World J Urol 2007 Nov

Vascular endothelial growth factor (VEGF) gene (VEGFA) polymorphism can predict the prognosis in acute myeloid leukaemia patients
Kim DH, et al.
Br J Haematol 2007 Nov

No Association of Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism  in Susceptibility to Gallbladder Cancer
Srivastava A, et al.
DNA Cell Biol 2007 Nov

MCP-1 Promoter Polymorphism at 2518 Is Associated with Metastasis of Nasopharyngeal Carcinoma after Treatment
Tse KP, et al.
Clin Cancer Res 2007 Nov;13(21):6320-6

Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis
Decock J, et al.
Cancer Res 2007 Nov;67(21):10214-21

CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women
Yoon KA, et al.
Lung Cancer 2007 Nov

A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer risk
Talbott KE, et al.
Breast Cancer Res Treat 2007 Nov

A polymorphism in the G protein beta3-subunit gene is associated with bone metastasis risk in breast cancer patients
Clar H, et al.
Breast Cancer Res Treat 2007 Nov

Selected Base Excision Repair Gene Polymorphisms and Susceptibility to Biliary Tract Cancer and Biliary Stones: A Population-Based Case-Control Study in China
Huang WY, et al.
Carcinogenesis 2007 Nov

Epstein-Barr virus infection and single nucleotide polymorphisms in the promoter  region of interleukin 10 gene in patients with Hodgkin lymphoma
da Silva GN, et al.
Arch Pathol Lab Med 2007 Nov;131(11):1691-6

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population
Boccia S, et al.
Biomarkers 2007 Nov-2007 Dec;12(6):635-44

Genetic variation in interleukin-10 gene and risk of oral cancer
Yao JG, et al.
Clin Chim Acta 2007 Oct

 

Endocrine, Nutritional and Metabolic Diseases

STAT1 gene variations, IgE regulation and atopy
Pinto LA, et al.
Allergy 2007 Dec;62(12):1456-61

Oatp1b1 polymorphism is a major determinant of serum bilirubin level but not associated with rifampicin-mediated bilirubin elevation
Zhang W, et al.
Clin Exp Pharmacol Physiol 2007 Dec;34(12):1240-4

Associations between 45t/g polymorphism of the adiponectin gene and plasma adiponectin levels with type 2 diabetes
Li LL, et al.
Clin Exp Pharmacol Physiol 2007 Dec;34(12):1287-90

Genetic polymorphisms associated with cigarette smoking and the risk of Graves' Disease
Bufalo NE, et al.
Clin Endocrinol (Oxf) 2007 Nov

Flutamide metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotype
Ong KK, et al.
Eur J Endocrinol 2007 Nov;157(5):661-8

Association of adipose most abundant transcript 1 (apM1) gene with type 2 diabetes mellitus in a Chinese population: A Meta-analysis of case-control studies
Li S, et al.
Clin Endocrinol (Oxf) 2007 Nov

Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations
Ma J, et al.
Eur J Endocrinol 2007 Nov;157(5):641-5

Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the  metabolic syndrome
Lindner I, et al.
Mol Nutr Food Res 2007 Nov

Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: Clinical and immunologic outcomes  in heterozygotes
Zhang L, et al.
J Allergy Clin Immunol 2007 Nov;120(5):1178-85

Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study
Wu K, et al.
Eur Heart J 2007 Nov

Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid  metabolism
Caspi A, et al.
Proc Natl Acad Sci U S A 2007 Nov

 

Diseases of the Blood & Blood-Forming Organ Disorders

Prevalence of thrombotic risk factors among beta-thalassemia patients from Western Iran
Rahimi Z, et al.
J Thromb Thrombolysis 2007 Nov

 

Mental Disorders

The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults
Kilpatrick DG, et al.
Am J Psychiatry 2007 Nov;164(11):1693-9

Genetic variation in mu-opioid-receptor-interacting proteins and smoking cessation in a nicotine replacement therapy trial
Ray R, et al.
Nicotine Tob Res 2007 Nov;9(11):1237-41

Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use
Zammit S, et al.
Br J Psychiatry 2007 Nov;191:402-7

 

Diseases of the Nervous System and Sense Organs

Nonsynonymous Polymorphisms of Histamine-Metabolising Enzymes in Patients with Parkinson's Disease
Agundez JA, et al.
Neuromolecular Med 2007 Nov

Sorl1 as an Alzheimer's Disease Predisposition Gene?
Webster JA, et al.
Neurodegener Dis 2007 Nov

Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly
Miyajima F, et al.
Genes Brain Behav 2007 Oct

 

Diseases of the Circulatory System

Association of alpha-adducin Gly460Trp polymorphism with coronary artery disease  in a Korean population
Cha SH, et al.
J Hypertens 2007 Dec;25(12):2413-20

Association between factor V Leiden mutation and coronary artery disease in the northeast region of Turkey
Gurlertop HY, et al.
Blood Coagul Fibrinolysis 2007 Dec;18(8):719-22

Effect of Variation in CYP11B1 and CYP11B2 on Corticosteroid Phenotype and Hypothalamic-Pituitary-Adrenal Axis Activity in Hypertensive and Normotensive Subjects
Freel EM, et al.
Clin Endocrinol (Oxf) 2007 Nov

Natriuretic Peptide Precursor A Gene Polymorphisms and Risk of Blood Pressure Progression and Incident Hypertension
Conen D, et al.
Hypertension 2007 Nov

The association of interleukin-18 genotype and serum levels with metabolic risk factors for cardiovascular disease
Evans J, et al.
Eur J Endocrinol 2007 Nov;157(5):633-40

The polymorphism in acetaldehyde dehydrogenase 2 gene, causing a substitution of  glu > lys(504), is not associated with coronary atherosclerosis severity in han chinese
Xu F, et al.
Tohoku J Exp Med 2007 Nov;213(3):215-20

Variation in inflammation-related genes and risk of incident nonfatal myocardial  infarction or ischemic stroke
Bis JC, et al.
Atherosclerosis 2007 Nov

Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study
Shiffman D, et al.
Arterioscler Thromb Vasc Biol 2007 Nov

 

Diseases of the Respiratory System

Genetic effect of CCR3 and IL5RA gene polymorphisms on eosinophilia in asthmatic  patients
Lee JH, et al.
J Allergy Clin Immunol 2007 Nov;120(5):1110-7

 

Diseases of the Digestive System

Association between promoter polymorphisms of nuclear factor-erythroid 2-related  factor 2 gene and peptic ulcer diseases
Arisawa T, et al.
Int J Mol Med 2007 Dec;20(6):849-53

Association of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation/Variant/Haplotype and Tumor Necrosis Factor (TNF) Promoter Polymorphism  in Hyperlipidemic Pancreatitis
Chang YT, et al.
Clin Chem 2007 Nov

DMBT1 Confers Mucosal Protection In Vivo and a Deletion Variant Is Associated With Crohn's Disease
Renner M, et al.
Gastroenterology 2007 Nov;133(5):1499-509

1007fs, G908R, R702W Mutations and P268S, IVS8(+158) Polymorphisms of the CARD15  Gene in Turkish Inflammatory Bowel Disease Patients and Their Relationship with Disease-Related Surgery
Ince AT, et al.
Dig Dis Sci 2007 Nov

SPARC Gene Polymorphism in Renal Transplant Patients With Gingival Overgrowth
Drozdzik A, et al.
J Periodontol 2007 Nov;78(11):2185-9

 

Diseases of the Genitourinary System

Comprehensive and rapid genotyping of mutations and haplotypes in congenital bilateral absence of the vas deferens and other cystic fibrosis transmembrane conductance regulator-related disorders
Bareil C, et al.
J Mol Diagn 2007 Nov;9(5):582-8

The Androgen Receptor CAG Repeat Length Polymorphism Associates with Prostate Volume in Finnish Men with Benign Prostatic Hyperplasia
Renko O, et al.
DNA Cell Biol 2007 Nov

Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System and Angiotensin II Type 1-Receptor Activating Antibodies in Renal Rejection
Zhang G, et al.
Tohoku J Exp Med 2007 Nov;213(3):203-14

 

Diseases of the Musculoskeletal System and Connective Tissue

Polymorphisms in the interleukin-6 receptor gene are associated with bone mineral density and body mass index in Spanish postmenopausal women
Bustamante M, et al.
Eur J Endocrinol 2007 Nov;157(5):677-84

Significant Association of Insertion/Deletion Polymorphism of the Angiotensin-Converting Enzyme Gene with Rheumatoid Arthritis
Uppal SS, et al.
J Rheumatol 2007 Nov

Frequency of HLA-B27 alleles in Brazilian patients with psoriatic arthritis
Bonfiglioli R, et al.
Clin Rheumatol 2007 Nov

Genetic Contribution to Carotid Vascular Disease in Patients with Systemic Lupus  Erythematosus
Marasini B, et al.
J Clin Immunol 2007 Nov

Association Between the T-786C eNOS Polymorphism and Idiopathic Osteonecrosis of  the Head of the Femur
Glueck CJ, et al.
J Bone Joint Surg Am 2007 Nov;89(11):2460-8

Rheumatoid arthritis association at 6q23
Thomson W, et al.
Nat Genet 2007 Nov

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
Plenge RM, et al.
Nat Genet 2007 Nov

CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythematosus
Mamtani M, et al.
Ann Rheum Dis 2007 Nov

 

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