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 Thursday, November 8, 2007 Volume 19   Number 19
update banner Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events

The 6th Georgia Tech- ORNL International Conference on Bioinformatics. In silico Biology: Gene Discovery and Systems Genomics non-gov warning icon

Fourteenth Meeting of the Secretary's Advisory Committee on Genetics, Health, and Society 

Genetics and Mechanisms of Susceptibility to Infectious Diseases non-gov warning icon



 Let's Go Surfing

Family Health History Newsletter, Michigan Department of Community Health  non-gov warning icon (last accessed 2/2008)

My Family Health
Portrait, U.S. Surgeon General

Diabetes is a Family Affair Campaign  non-gov warning icon

mother and daughter

When is BRCA Genetic Testing for Breast and Ovarian Cancer Appropriate?
The U.S. Preventive Services Task Force (USPSTF) recommends against routine referral for BRCA testing if a woman’s

family history does not suggest an increased risk for harmful BRCA mutations. The USPSTF recommends that women with a family history associated with an increased risk for BRCA mutations be referred to suitably trained health care providers.
Read the USPSTF recommendations PDF icon (142KB) & clinical considerations.

Genomics Announcements
   
CDC-sponsored event

New Genomics Forum of the American Public Health Association was approved this month. Interested individuals can join for free.  non-gov warning icon

   
CDC-sponsored event

The Secretary’s Advisory Committee on Genetics, Health, and Society invites input on the Committee’s draft report, U.S. System of Oversight of Genetic Testing: A Response to the Charge of the Secretary of HHS, by December 21, 2007.

   
CDC-sponsored event
What's New in HuGENet™
November 2007


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Five facts about genetics and
cancer
non-gov warning icon Lansing State Journal, November 7

Study identifies novel gene alterations in lung cancernon-gov warning icon NIH News, November 4

New role for p53 gene in childhood cancernon-gov warning icon News-Medical.Net, November 6

 

line

Cardiovascular Disease

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heartnon-gov warning icon Science Daily, November 2

Researchers discover new gene responsible for Brugada syndromenon-gov warning icon News-Medical.Net, November 1

line

Ethical, Legal and Social Issues (ELSI)

U. to launch center for genetic ethicsnon-gov warning icon The Daily Pennsylvanian, November 5

line

Genetic Testing

DIY genetic test: I want to know the
worst
non-gov warning icon The Independent, November 6

Is there a heart attack in your futurenon-gov warning icon Yahoo Finance, November 6

Govt. calls for better genetic testing regulationnon-gov warning icon MSNBC, November 6

Genetic testing rarely used but effective weapon to prevent diseasenon-gov warning icon (last accessed 2/2008) Gulfnews.com, November 2

line

Mental Health

Results of gene study could lead to tailored treatment for depressionnon-gov warning icon Medical News Today, November 8

Unique database mapping 'expression' of genes in the brain could lead to new, targeted
treatments
non-gov warning icon Medical News Today, November 5

line

Obesity

"Nutrigenetic" diets may aid weight loss: studynon-gov warning icon Reuters Health, November 7

line

Other News

World experts gather in Cambridge to bid to unravel MS genes, UKnon-gov warning icon Medical News Today, November 8

When it comes to brain power for some babies breast is definitely bestnon-gov warning icon News-Medical.Net, November 6

Genome sequencing center opens in Santa Fenon-gov warning icon Web Wire, November 6

Researchers identify gene behind rheumatoid arthritisnon-gov warning icon News-Medical.Net, November 5

Expanded access program for treatment of PKU, a rare genetic metabolic disordernon-gov warning icon Medical News Today, November 6

Genes play important role in risk for dependence on illicit and licit drugsnon-gov warning icon EurekAlert, November 5

Gene expression profiling of dengue virus infection in cell lines and patientsnon-gov warning icon Medical News Today, November 6

XX. International Congress of Genetics (ICG) in Berlin from July 12-17, 2008non-gov warning icon www.uni-protokolle.de, November 5

Researchers chart the genetic mechanisms behind the genesis of fat cellsnon-gov warning icon EurekAlert, November 6

Genetic mapping: By the numbersnon-gov warning icon
MercuryNews.com, November 4

UMC takes part in largest ever study of child and human healthnon-gov warning icon News-Medical.Net, November 6

The brother and sister, aged 11 and 9, doomed to die early of genetic disordernon-gov warning icon Daily Mail, November 1

line
Genomics in Scientific Literature
Featured Item

Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid  metabolism
Caspi A, et al.
Proc Natl Acad Sci U S A 2007 Nov

 General Articles

Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges
Wilke RA, et al.
Nat Rev Drug Discov 2007 Nov;6(11):904-16

Investigating gene environment interaction in complex diseases: increasing power  by selective sampling for environmental exposure
Boks MP, et al.
Int J Epidemiol 2007 Oct

Testing and Estimating Gene-Environment Interactions in Family-Based Association  Studies
Vansteelandt S, et al.
Biometrics 2007 Oct

The role of circadian clock genes in mental disorders
Lamont EW, et al.
Dialogues Clin Neurosci 2007;9(3):333-42

Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer
Newcomb PA, et al.
Cancer Epidemiol Biomarkers Prev 2007 Nov

Sequentially testing for a gene-drug interaction in a genomewide analysis
Kelly P, et al.
Stat Med 2007 Nov

Use of whole-genome association scans in disease gene identification, drug discovery and development
Roses AD, et al.
IDrugs 2007 Nov;10(11):797-804

How Risk is Perceived, Constructed and Interpreted by Clients in Clinical Genetics, and the Effects on Decision Making: Systematic Review
Sivell S, et al.
J Genet Couns 2007 Oct

Human Genetics: The Hidden Text of Genome-wide Associations
Gibson G & Goldstein DB
Curr Biol 2007 Nov;17(21):R929-32

 

 Family History

Cholesterol screening in school children: is family history reliable to choose the ones to screen?
Derinoz O, et al.
Acta Paediatr 2007 Oct

Family history of breast or ovarian cancer modifies the risk of secondary leukemia after breast cancer: Results from a population-based study
Verkooijen HM, et al.
Int J Cancer 2007 Oct

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending November 7, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Musculoskeletal System and Connective Tissue

For more information on HuGE, please visit the HuGENet™ home page

 

 

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