Section Contents

First-Line Medications

Case Contents

Table of Contents

How to Use the Course

Mass Casualty Events

Cholinesterase Inhibitors

Pathological Conditions

Cholinergic Toxidrome

Nicotinic Receptors

Muscarinic Receptors

Nicotinic/Muscarinic Mixture

Signs and Symptoms

Laboratory Tests

Differential Diagnosis

Pediatric Cases

Exposure History

RBC & Serum Tests

Inhibitors & Byproducts

Management Strategies

Secondary Exposure

Supportive Care

First-Line Medications

Medications: Atropine

Medications: Pralidoxime

Medications: Diazepam

Antidote Stocking

Deprecated Treatments

Medico-Legal Issues

Intermediate Syndrome

Delayed Neuropathy

Chronic Neurotoxicity

Literature Cited

Related Documents

MMG: Nerve Agents

ToxFAQs™: Nerve Agents

Case Studies (CSEM)

Continuing Education

Online Registration

ATSDR Resources

Case Studies (CSEM)

Exposure Pathways

Health Assessments

Health Statements

Interaction Profiles

Interactive Learning

Managing Incidents

Medical Guidelines

Minimal Risk Levels

ToxFAQs™ CABS

Toxicological Profiles

Toxicology Curriculum

External Resources

Agency for Toxic Substances and Disease Registry
Case Studies in Environmental Medicine (CSEM)

Cholinesterase Inhibitors
Including Insecticides and Chemical Warfare Nerve Agents
Part 4: The Cholinergic Toxidrome
Section 11: Management of the Cholinergic Toxidrome
Management Strategy 3: Medications

Three First-Line Medications

Three first-line medications are recommended for cholinesterase inhibitor toxicity. These will be discussed in detail in the following sections.

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Revised 2007-10-16.