October is National Breast Cancer Awareness Month. See the USPSTF recommendations on BRCA mutation testing for breast and ovarian cancer susceptibility, and learn more about breast cancer from the CDC and NIH.
	NIH's National Institute on Alcohol Abuse and Alcoholism is now accepting applications for projects on epigenomics of human health and disease. Read the announcement.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cancer
Genetic analysis predicts whether liver cancer likely to recur, Medical News Today, October 16	Is breast cancer in your genes, WSLS10, October 14
Prostate cancer gene test provides new early detection - urine test may reduce needless and expensive biopsies, Medical News Today, October 16	New approach to genetic testing could halve deaths from inherited bowel cancer, Science Daily, October 13
Yale scientists identify genetic marker to predict lung cancer risk, Medical News Today, October 15	Two more genes linked to common skin cancer, Medline Plus, October 13
Health matters, The Chronicle, October 14	Keeping abreast, Herald Sun, October 12

The regulation of direct-to-consumer genetic tests Kaye J Hum Mol Genet 2008 Oct;17(R2):R180-3

{alpha}1-Antitrypsin Augmentation Therapy for PI*MZ Heterozygotes: A Cautionary Note
Sandhaus RA, et al.
Chest 2008 Oct;134(4):831-4

Proceedings of the International Consensus Conference on Breast Cancer Risk, Genetics, & Risk Management, April, 2007
Schwartz GF, et al.
Cancer 2008 Oct

Comparison of population-based association study methods correcting for population stratification
Zhang F, et al.
PLoS ONE 2008;3(10):e3392

Genome-wide association studies: potential next steps on a genetic journey
McCarthy MI & Hirschhorn JN
Hum Mol Genet 2008 Oct;17(R2):R156-65

Accounting for ancestry: population substructure and genome-wide association studies
Tian C, et al.
Hum Mol Genet 2008 Oct;17(R2):R143-50

Extending genome-wide association studies to copy-number variation
McCarroll SA
Hum Mol Genet 2008 Oct;17(R2):R135-42

Using gene expression to investigate the genetic basis of complex disorders
Nica AC & Dermitzakis ET
Hum Mol Genet 2008 Oct;17(R2):R129-34

Practical aspects of imputation-driven meta-analysis of genome-wide association studies
de Bakker PI, et al.
Hum Mol Genet 2008 Oct;17(R2):R122-8

Autoimmune diseases: insights from genome-wide association studies
Lettre G & Rioux JD
Hum Mol Genet 2008 Oct;17(R2):R116-21

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants
Mohlke KL, et al.
Hum Mol Genet 2008 Oct;17(R2):R102-8

Nutrients: the environmental regulation of cardiovascular gene expression
Minieri M & Di Nardo P
Genes Nutr 2007 Nov;2(2):163-8

Overview of genes, diet and cancer
Mathers JC
Genes Nutr 2007 Oct;2(1):67-70

NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure-A literature review
Dougherty D, et al.
Toxicol Lett 2008 Sep

Accuracy of predicting the genetic risk of disease using a genome-wide approach
Daetwyler HD, et al.
PLoS ONE 2008;3(10):e3395

Genome-based prediction of common diseases: advances and prospects
Janssens AC & van Duijn CM
Hum Mol Genet 2008 Oct;17(R2):R166-73

Genes, diet and public health
Seedorf U, et al.
Genes Nutr 2007 Oct;2(1):75-80

Genetic susceptibility to radiogenic cancer in humans
Allan JM
Health Phys 2008 Nov;95(5):677-86

The Role of Pharmacogentics in Treating Central Nervous System Disorders
Patnaik M, et al.
Exp Biol Med (Maywood) 2008 Oct

Genetic association studies in nursing practice and scholarship
Underwood PC & Read CY
J Nurs Scholarsh 2008;40(3):212-8

Risk for multiple sclerosis in relatives and spouses of patients diagnosed with autoimmune and related conditions
Hemminki K, et al.
Neurogenetics 2008 Oct

Differences in Estrogen Receptor Subtype According to Family History of Breast Cancer among Hispanic, but not Non-Hispanic White Women
Hines LM, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2700-6

 

Patient-Specific Decision-Making for Warfarin Therapy in Nonvalvular Atrial Fibrillation. How Will Screening With Genetics and Imaging Help?
Eckman MH, et al.
Stroke 2008 Oct

Hereditary breast cancer: from bench to bedside
De Greve J, et al.
Curr Opin Oncol 2008 Nov;20(6):605-13

 

Does parental expressed emotion moderate genetic effects in ADHD? an exploration  using a genome wide association scan
Sonuga-Barke EJ, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 Oct

Male-pattern baldness susceptibility locus at 20p11
Richards JB, et al.
Nat Genet 2008 Oct

Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits
Stacey SN, et al.
Nat Genet 2008 Oct

Genome wide identification of recessive cancer genes by combinatorial mutation analysis
Volinia S, et al.
PLoS ONE 2008;3(10):e3380

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus
Weidinger S, et al.
PLoS Genet 2008 Aug;4(8):e1000166

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending October 15, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page