Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
October 16, 2008
Volume 21, No. 16

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.

Gene Variant Frequency

The Prevalence of Methylenetetrahydrofolate Reductase 677 C-T, Factor V 1691 G-A, and Prothrombin 20210 G-A Mutations in Healthy Populations in Setif, Algeria
Bouroba R, et al.
Clin Appl Thromb Hemost 2008 Oct

New sequence variants in BRCA1 and BRCA2 genes detected by high-resolution melting analysis in an elderly healthy female population in Croatia
Cvok ML, et al.
Clin Chem Lab Med 2008;46(10):1376-83

 

Infectious and Parasitic Diseases

Polymorphisms in the Mannan-Binding Lectin Gene Are Not Associated with Questionnaire-Reported Respiratory Tract Infections in Children
Ruskamp JM, et al.
J Infect Dis 2008 Oct

Associations of Chemokine Receptor Polymorphisms With HIV-1 Mother-to-Child Transmission in Sub-Saharan Africa: Possible Modulation of Genetic Effects by Antiretrovirals
Singh KK, et al.
J Acquir Immune Defic Syndr 2008 Oct

DC-SIGNR polymorphisms and its association with HIV-1 infection.
Wang H, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008 Oct;25(5):542-5

 

Neoplasms

Association of Genetic Polymorphisms in Vitamin D Receptor Gene and Susceptibility to Sporadic Prostate Cancer
Onen IH, et al.
Exp Biol Med (Maywood) 2008 Oct

The Val allele of HER-2 codon 655 predicts the progression of oral squamous cell  carcinoma
Wu CH, et al.
Oral Oncol 2008 Oct

Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women
Liang J, et al.
Carcinogenesis 2008 Oct

Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk
Suzuki T, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2742-7

PTPRJ Haplotypes and Colorectal Cancer Risk
Toland AE, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2782-5

5-lipoxygenase and 5-lipoxygenase-activating protein gene polymorphisms, dietary  linoleic Acid, and risk for breast cancer
Wang J, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2748-54

Genetic variation in calcium-sensing receptor and risk for colon cancer
Dong LM, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2755-65

Cyclin D1 Pro241Pro (CCND1-G870A) Polymorphism Is Associated with Increased Cancer Risk in Human Populations: A Meta-Analysis
Pabalan N, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2773-81

XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response to platinum-based neoadjuvant chemotherapy in cervical cancer
Kim K, et al.
Gynecol Oncol 2008 Oct

HSD17B1 Genetic Variants and Hormone Receptor-Defined Breast Cancer
Gaudet MM, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2766-72

A Prospective Study of Dietary Folate and Vitamin B and Colon Cancer According to Microsatellite Instability and KRAS Mutational Status
Schernhammer ES, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2895-8

 

Endocrine, Nutritional and Metabolic Diseases

Analysis of Polymorphisms in Olive Pollen Allergy: IL13, IL4RA, IL5 and ADRB2 Genes
Llanes E, et al.
Int Arch Allergy Immunol 2008 Oct;148(3):228-38

Absence of association of the L296Q polymorphism in the cholesteryl ester transfer protein gene with type 2 diabetes mellitus in Chinese.
Gao Y, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008 Oct;25(5):555-9

Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes
Kawasaki E, et al.
Diabetologia 2008 Oct

Increasing Heritability of BMI and Stronger Associations With the FTO Gene Over Childhood
Haworth CM, et al.
Obesity (Silver Spring) 2008 Oct

Genetic Variation in ABC G5/G8 and NPC1L1 Impact Cholesterol Response to Plant Sterols in Hypercholesterolemic Men
Zhao HL, et al.
Lipids 2008 Oct

No Association of PTPN1 Polymorphisms With Macronutrient Intake and Measures of Adiposity
Bauer F, et al.
Obesity (Silver Spring) 2008 Oct

The fat mass- and obesity-associated locus and dietary intake in children
Timpson NJ, et al.
Am J Clin Nutr 2008 Oct;88(4):971-8

Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes
Grant SF, et al.
Diabetes 2008 Oct

The search for putative unifying genetic factors for components of the metabolic  syndrome
Sjogren M, et al.
Diabetologia 2008 Oct

Gene variants influencing measures of inflammation or predisposing to autoimmune  and inflammatory diseases are not associated with the risk of type 2 diabetes
Rafiq S, et al.
Diabetologia 2008 Oct

Relationship Between Functional Promoter Polymorphism in the XBP1 Gene (-116C/G)  and Obesity
Yilmaz E, et al.
Clin Appl Thromb Hemost 2008 Oct

CETP TaqIB polymorphism in Turkish adults: association with dyslipidemia and metabolic syndrome
Ozsait B, et al.
Anadolu Kardiyol Derg 2008 Oct;8(5):324-30

 

Mental Disorders

Genetic association between -93A/G polymorphism in the Fyn kinase gene and alcohol dependence in Spanish men
Pastor IJ, et al.
Eur Psychiatry 2008 Oct

The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population
Zhang K, et al.
J Affect Disord 2008 Oct

Association of HPA axis genes with suicidal behaviour in schizophrenia
De Luca V, et al.
J Psychopharmacol 2008 Oct

Functional serotonin 1A receptor variant influences treatment response to atypical antipsychotics in schizophrenia
Mossner R, et al.
Pharmacogenet Genomics 2008 Oct

Association of the Apolipoprotein E Gene, Its Promoter Polymorphisms and Haplotypes with Depressive Symptoms. The Cardiovascular Risk in Young Finns Study
Elovainio M, et al.
Neuropsychobiology 2008 Oct;58(2):91-6

Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity
Verhagen M, et al.
Mol Psychiatry 2008 Oct

Brain-Derived Neurotrophic Factor Val/Met Polymorphism and Bipolar Disorder. Association of the Met Allele with Suicidal Behavior of Bipolar Patients
Kim B, et al.
Neuropsychobiology 2008 Oct;58(2):97-103

ADRA2A polymorphism and smoking in a Turkish population
Karahalil B, et al.
Toxicol Ind Health 2008 Apr;24(3):171-6

 

Diseases of the Nervous System and Sense Organs

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study
Ennis S, et al.
Lancet 2008 Oct

Deficiency of CARD8 Is Associated with Increased Alzheimer's Disease Risk in Women
Fontalba A, et al.
Dement Geriatr Cogn Disord 2008 Oct;26(3):247-50

Apolipoprotein E Polymorphism and Brain Morphology in Mild Cognitive Impairment
Thomann PA, et al.
Dement Geriatr Cogn Disord 2008 Oct;26(4):300-5

Fine mapping and association studies in a candidate region for autism on chromosome 2q31-q32
Conroy J, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 Oct

Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis
Paubel A, et al.
Arch Neurol 2008 Oct;65(10):1333-6

Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism  with the susceptibility of Parkinson's disease.
Xiao Y & Zhang B
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008 Oct;25(5):586-7

Association of the DJ-1 gene polymorphism with sporadic Parkinson's disease in Sichuan province of China.
Chen W, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008 Oct;25(5):566-9

Analysis of APBB2 gene polymorphisms in sporadic Alzheimer's disease
Golanska E, et al.
Neurosci Lett 2008 Oct

Association of GSK3B with Alzheimer disease and frontotemporal dementia
Schaffer BA, et al.
Arch Neurol 2008 Oct;65(10):1368-74

Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia
Sleegers K, et al.
Hum Mutat 2008 Oct

CYP1B1 and MYOC mutations in 116 Chinese patients with primary congenital glaucoma
Chen Y, et al.
Arch Ophthalmol 2008 Oct;126(10):1443-7

Genetic study of eight AKT1 gene polymorphisms and their interaction with DRD2 gene polymorphisms in tardive dyskinesia
Zai CC, et al.
Schizophr Res 2008 Oct

Synergistic Effect of Heme Oxygenase-1 and Tau Genetic Variants on Alzheimer's Disease Risk
Mateo I, et al.
Dement Geriatr Cogn Disord 2008 Oct;26(4):339-42

The Q7R polymorphism in the saitohin gene is rare in a southern Chinese population
Lin K, et al.
Neurol Sci 2008 Oct

 

Diseases of the Circulatory System

A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men
Adamzik M, et al.
Basic Res Cardiol 2008 Nov;103(6):598-610

FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
Martinelli N, et al.
Am J Clin Nutr 2008 Oct;88(4):941-9

Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction
Allayee H, et al.
Am J Clin Nutr 2008 Oct;88(4):934-40

Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the  Southern German population
Arnold ML, et al.
Thromb Haemost 2008 Oct;100(4):614-7

Association of genetic variation in apolipoprotein E and low density lipoprotein  receptor with ischemic stroke in Northern Han Chinese
Wang B, et al.
J Neurol Sci 2008 Oct

G protein beta3 subunit gene polymorphism in Turkish hypertensives
Alioglu E, et al.
Anadolu Kardiyol Derg 2008 Oct;8(5):331-5

Ambulatory Blood Pressure Is Associated With Polymorphic Variation in P2X Receptor Genes
Palomino-Doza J, et al.
Hypertension 2008 Oct

 

Diseases of the Respiratory System

Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia
Patwari PP, et al.
Pediatr Crit Care Med 2008 Oct

Polymorphisms of aquaporin5 gene in chronic obstructive pulmonary disease in a Chinese population
Ning Y, et al.
Swiss Med Wkly 2008 Oct;138(39-40):573-8

MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis
Checa M, et al.
Hum Genet 2008 Oct

 

Diseases of the Genitourinary System

Mutation analysis of the Uromodulin gene in 96 individuals with urinary tract anomalies (CAKUT)
Wolf MT, et al.
Pediatr Nephrol 2008 Oct

Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility
Gunel-Ozcan A, et al.
Mol Biol Rep 2008 Oct

 

Complications of Pregnancy, Childbirth, and the Puerperium

Maternal thrombophilia and the risk of recurrence of preeclampsia
Facchinetti F, et al.
Am J Obstet Gynecol 2008 Oct

 

Diseases of the Musculoskeletal System and Connective Tissue

Different Genetic Effects of Interferon Regulatory Factor 5 (IRF5) Polymorphisms  on Systemic Lupus Erythematosus in a Korean Population
Shin HD, et al.
J Rheumatol 2008 Oct

Associations Between FCGR3A Polymorphisms and Susceptibility to Rheumatoid Arthritis: A Metaanalysis
Lee YH, et al.
J Rheumatol 2008 Oct

Putative Role of Functional Interferon Regulatory Factor 5 (IRF5) Polymorphism in Rheumatoid Arthritis in a Korean Population
Kim YJ, et al.
J Rheumatol 2008 Oct

MEFV Mutations Modify the Clinical Presentation of Henoch-Schonlein Purpura
Ozcakar ZB, et al.
J Rheumatol 2008 Oct

Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis
Harrison P, et al.
Rheumatology (Oxford) 2008 Oct

 

Certain Conditions Originating in the Perinatal Period

Smoking and Human Reproduction: The Effect of Adenylate Kinase Genetic Polymorphism
Gloria-Bottini F, et al.
Am J Perinatol 2008 Oct

 

Symptoms, Signs and Ill-defined Conditions

The FTO gene and measured food intake in children
Wardle J, et al.
Int J Obes (Lond) 2008 Oct

Efficacy of ER-alpha Polymorphisms and the Intrafollicular IGF System for Predicting Pregnancy in IVF-ET Patients
Choi YS, et al.
Gynecol Obstet Invest 2008 Oct;67(2):73-80

 

Injury and Poisoning

Modulating effect of apolipoprotein E polymorphisms on secondary brain insult and outcome after childhood brain trauma
Lo TY, et al.
Childs Nerv Syst 2008 Oct

Genetic Polymorphisms, Messenger RNA Expression of p53, p21, and CCND1, and Possible Links with Chromosomal Aberrations in Chinese Vinyl Chloride-Exposed Workers
Qiu YL, et al.
Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2578-84

Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population
Wu F, et al.
Toxicol Appl Pharmacol 2008 Sep

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC National Office of Public Health Genomics makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: October 16, 2008 (archived document)
Content Source: National Office of Public Health Genomics