November is Family Health History Awareness Month.
	New report, Personalized Health Care: Pioneers, Partnerships, Progress, released by the U.S. Department of Health and Human Services in November 2008.
	New publication, The Evidence Dilemma in Genomics Medicine, in the November-December 2008 thematic issue on medical technology of Health Affairs, written by Muin J. Khoury, MD, PhD. (Abstract only)
	New genetics fellowship position with CDC’s Division of Laboratory Systems in the National Center for Preparedness, Detection, and Control of Infectious Disease. Read the announcement. (75 KB) For more information, contact Ira Lubin at ilubin@cdc.gov.
	What's New in HuGENet™ November 2008

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases Boccia S, et al. Mutat Res 2008 Oct

Subjects matter: a survey of public opinions about a large genetic cohort study
Kaufman D, et al.
Genet Med 2008 Nov;10(11):831-9

The Role of the CAG Repeat Androgen Receptor Polymorphism in Andrology
Zitzmann M
Front Horm Res 2009;37:52-61

Can geneticists help clinicians to understand and treat non-autoimmune diabetes?
Malecki MT, et al.
Diabetes Res Clin Pract 2008 Nov

Chapter 1 common genetic variation and human disease
Orr N & Chanock S
Adv Genet 2008;62:1-32

Chapter 2 genetics of the framingham heart study population
Govindaraju DR, et al.
Adv Genet 2008;62:33-65

The SNPMaP package for R: A framework for genome-wide association using DNA pooling on microarrays
Davis OS, et al.
Bioinformatics 2008 Nov

Ranking single nucleotide polymorphisms by potential deleterious effects
Lee PH & Shatkay H
AMIA Annu Symp Proc 2008:667-71

Polygenic model for predicting breast cancer risk via genome-wide polymorphisms
Piccolo S
AMIA Annu Symp Proc 2008:1094

Correlating phenotype and genotype in autism spectrum disorder research
McMurry A, et al.
AMIA Annu Symp Proc 2008:894

AutDB: a gene reference resource for autism research
Basu SN, et al.
Nucleic Acids Res 2008 Nov

Environmental and genetic risk factors in obesity
Hebebrand J & Hinney A
Child Adolesc Psychiatr Clin N Am 2009 Jan;18(1):83-94

Environmental and genetic risk factors for eating disorders: what the clinician needs to know
Mazzeo SE & Bulik CM
Child Adolesc Psychiatr Clin N Am 2009 Jan;18(1):67-82

GENESTAT: an information portal for design and analysis of genetic association studies
Ripatti S, et al.
Eur J Hum Genet 2008 Nov

Genetic dissection of type 2 diabetes
Ridderstrale M & Groop L
Mol Cell Endocrinol 2008 Oct

Identifying genes for primary hypertension: methodological limitations and gene-environment interactions
Franks PW
J Hum Hypertens 2008 Nov

Genetic association analysis with FAMHAP: a major program update
Herold C & Becker T
Bioinformatics 2008 Nov

Sweat chloride testing in infants identified as heterozygote carriers by newborn  screening
Soultan ZN, et al.
J Pediatr 2008 Dec;153(6):857-9

A framework for interpreting genome-wide association studies of psychiatric disorders
Mol Psychiatry 2008 Nov

Declining brain glucose metabolism in normal individuals with a maternal history  of Alzheimer disease
Mosconi L, et al.
Neurology 2008 Nov

Analysis of Family Health History Data Collection Patterns in Consumer-Oriented Web-based Tools
Hulse NC, et al.
AMIA Annu Symp Proc 2008:982

Ideal features for a patient-entered family history and risk assessment tool
Taylor DP, et al.
AMIA Annu Symp Proc 2008:1152

Aggregation of lipoprotein and inflammatory parameters in families with a history of premature myocardial infarction: the Tallinn Myocardial Infarction Study
Aasvee K, et al.
Clin Chem Lab Med 2008;46(11):1602-8

Usability test of a family health history web tool
Huang Y, et al.
AMIA Annu Symp Proc 2008:981

Instance testing of the family history ontology
Peace J & Brennan P
AMIA Annu Symp Proc 2008:1088

 

Test for LRRK2 mutations in patients with Parkinson's disease
Healy DG, et al.
Pract Neurol 2008 Dec;8(6):381-5

Physicians' Experiences With BRCA1/2 Testing in Community Settings
Keating NL, et al.
J Clin Oncol 2008 Nov

Factors associated with intrusive cancer-related worries in women undergoing cancer genetic risk assessment
Bennett P, et al.
Fam Cancer 2008 Nov

Comparing test-specific distress of susceptibility versus deterministic genetic testing for Alzheimer's disease
Cassidy MR, et al.
Alzheimers Dement 2008 Nov;4(6):406-13

The genetic basis of hereditary medullary thyroid cancer: clinical implications for the surgeon, with a particular emphasis on the role of prophylactic thyroidectomy
Sakorafas GH, et al.
Endocr Relat Cancer 2008 Dec;15(4):871-84

 

Genome wide association for nicotine dependence and smoking cessation success in  NIH research volunteers
Drgon T, et al.
Mol Med 2008 Nov

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
Baranzini SE, et al.
Hum Mol Genet 2008 Nov

Detection of Cryptic Pathogenic Copy Number Variations and Constitutional Loss of Heterozygosity using High Resolution SNP Microarray Analysis in 117 Patients Referred for Cytogenetic Analysis and Impact on Clinical Practice
Bruno DL, et al.
J Med Genet 2008 Nov

Role of the tau gene region chromosome inversion in progressive supranuclear palsy, corticobasal degeneration, and related disorders
Webb A, et al.
Arch Neurol 2008 Nov;65(11):1473-8

Meta-analysis of genome-wide association data identifies four new susceptibility  loci for colorectal cancer
Houlston RS, et al.
Nat Genet 2008 Nov

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
Mallal S, et al.
Lancet 2002 Mar;359(9308):727-32

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