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Selected Publications

Mass Spectrometry Group

  1. Vitorino R, Guedes S, Tomer K, Domingues P, Duarte J, Amado F, . On-plate digestion using a commercial microfraction collector for nano-HPLC matrix-assisted laser desorption/ionization tandem time-of-flight protein analysis. Analytical biochemistry 380(1):128-130, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18519023) Exit NIEHS
  2. Smedley III JG, Sharp JS, Kuhn JF, Tomer KB. Probing the pH-dependent prepore to pore transition of Bacillus anthracis protective antigen with differential oxidative protein footprinting. Biochemistry 47(40):10694-10704, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18785752) Exit NIEHS
  3. McEntee, M.F., Ziegler, C., Reel, D., Tomer, K., Shoieb, A., Raym M., Li, X., Neilsen, N., Lih, F.B., O'Rourke, D., Whelan, J. Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. The American journal of pathology, 173(1):229-241, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18556778) Exit NIEHS
  4. Deterding, L.J., Bunger, B.K., Banks, G.C., Tomer, K.B., Archer, T.K. Global changes in and characterization of specific sites of phosphorylation in mouse and human histone H1 Isoforms upon CDK inhibitor treatment using mass spectrometry. J Proteome Res., 7:2368-2379, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18416567) Exit NIEHS
  5. McEntee, M.F., C. Ziegler, D. Reel, K. Tomer, A. Shoieb, M. Ray, X. Li, N. Neilsen. F.B. Lih, D. O'Rourke, J. Whelan. Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. Am. J. Pathol., 173:229-241, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18556778?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  6. Siraki, A., L.Deterding, M. Bonini, J.-J. Jiang, M. Ehrenshaft, K. Tomer, R. Mason. Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. Chem. Res. Toxicol., 21:1143-1153, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18489081?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  7. Deterding, L.J., M.K. Bunger, G.C. Banks, K.B. Tomer, T.K. Archer. Global changes in and characterization of specific sites of phosphorylation in mouse and human histone h1 isoforms upon CDK inhibitor treatment using mass spectrometry. J. Proteome Res., 7:2368-2379, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18416567?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  8. Iacob, R.E., Z. Keck, O. Olson, S.K. Foung, K.B. Tomer. Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 glycoprotein. Biochim. Biophys. Acta-Proteins and Proteomics. 1784(3):530-542, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18230369?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  9. Iacob, R.E., I. Perdivara, M. Przybylski, K.B. Tomer. Mass spectrometric characterization of glycosylation of Hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans. J. Amer. Soc. Mass Spectrom., 19:428-444, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18187336?ordinalpos=15&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  10. Lardinois, O.M., C.D. Detweiler, K.B. Tomer, R.P. Mason, L.J. Deterding. Identifying the site of spin-trapping in proteins by a combination of liquid chromatography, ELISA and off-line tandem mass spectrometry. Free Rad. Biol & Med., 44:893-906, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18160050?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  11. Fostel, J., M. Waters, S. Stasiewicz, B.A. Merrick, K.B. Tomer, P. Bushel, R. Paules, N. Stegman, K. Yost, C. Johnson, S. Gustafson, S. Xirasagar, N. Xiao, C.-C. Huang, P. Boyer, D. Chan, Q. Pan, H. Gong, J. Taylor, D. Choi. CEBS: Chemical effects in biological systems. A public data repository integrating study design and toxicity data with microarray and proteomics data. Nuc. Acid Res., 36:D892-D900, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17962311?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  12. Cuthbertson, B.J., L.J. Deterding, J.G. Williams, K.B. Tomer,, K. Etienne, P.J. Blackshear, E.E. Büllesbach, P.S. Gross. Diversity in penaeidin antimicrobial peptide form and function. Devel. Comp. Immun., 32:167-181, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17716729?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  13. Perdivara, I., E. Sisu, I. Sisu, N. Dinca, K.B. Tomer, M. Przybylski, A.D. Zamfir. Enhanced electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry of long chain polysaccharides. Rap. Commun. Mass Spectrom., 22:773-782, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18275094?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Exit NIEHS
  14. Perdivara, I., L.J. Deterding, A. Moise, K.B. Tomer, M. Przybylski. Determination of primary structure and microheterogeneity of a β-amyloid plaque-specific antibody using high performance LC - tandem mass spectrometry. Analytical and bioanalytical chemistry 391(1):325-336, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18369607) Exit NIEHS
  15. Bhattacharjee, S., Deterding L.J., Jiang J.J., Bonini M.G., Tomer K.B., Ramirez D.C., Mason RP. Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. Journal of the American Chemical Society 129(44):13493-13501, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17939657) Exit NIEHS
  16. Deterding, L.J., S. Bhattacharjee, D.C. Rameriz, R.P. Mason, K.B. Tomer. Top-down and bottom-up mass spectrometric characterization of human myoglobin-centered free radicals induced by oxidative damage. Analytical chemistry 79(16):6236-6248, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17637042) Exit NIEHS
  17. Sharp, J.S., K.B. Tomer. Analysis of the oxidative damage-induced conformational changes of Apo- and Holo-calmodulin by dose-dependent protein oxidative surface mapping. Biophys. J., 92(5):1682-1692, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17158574) Exit NIEHS
  18. Cutalo, J.M., T.A. Darden, T.A. Kunkel, K.B. Tomer. Mapping the dimer interface in the C-terminal domains of the yeast MLH1-PMS1 heterodimer. Biochemistry, 45(51): 15458-15467, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17176067) Exit NIEHS
  19. Williams, J.G., C.E. Hioe, S. Zolla-Pazner, P.J. Norris, K.B. Tomer. The Antigenic Determinants on HIV p24 for CD4+ T Cell Inhibiting Antibodies as Determined by Limited Proteolysis, Chemical Modification, and Mass Spectrometry. J. Am. Soc. Mass Spectrom., 17:1560-1569, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16875837) Exit NIEHS
  20. Sharp, J.S., K.B. Tomer. Effects of anion proximity in peptide primary sequence on the rate and mechanism of leucine oxidation. Anal. Chem. 78:4885-4893, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16841907) Exit NIEHS
  21. Merrick, B.A., M.E. Bruno, J.H. Madenspacher, B.A. Wetmore, J. Foley, R. Pieper, M. Zhao, A.J. Makusky, A.M. McGrath, J.X. Zhou, J. Taylor, K.B. Tomer. Alterations in the rat serum proteome during liver injury from acetaminophen exposure. J. Pharm. Exp. Thera., 318:792-802, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16687475) Exit NIEHS
  22. Sharp, J.S., D.M. Sullivan, J. Cavanagh, K.B. Tomer. Measurement of multi-site oxidation kinetics reveals a specific conformational change in Spo0F as a result of protein oxidation. Biochem., 45:6260-6266, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16700537) Exit NIEHS
  23. Hager-Braun, C., H. Katinger, K.B. Tomer. The HIV-neutralizing monoclonal antibody 4E10 recognizes N-terminal sequences on the native antigen. J. Immunol., 176:7471-7481, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16751393) Exit NIEHS
  24. Xirasagar, S., S.F. Gustafson, C.-C. Huang, Q. Pan, J. Fostel, P. Boyer, B.A. Merrick, K.B. Tomer, D.D. Chan, K.J. Yost III, D.Choi, N. Xiao, S. Stasiewicz, P. Bushel, M.D. Waters. Chemical Effects in Biological Systems (CEBS) Object Model for Toxicology Data, Sys-Tox-OM: Design and Application. Bioinformatics, 22:874-882, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16410321) Exit NIEHS
  25. Ye, W., R. Sangaiah, D.E. Degen, A. Gold, K. Jayaraj, K.M. Koshlap, G. Boyesen, J. Williams, K.B. Tomer, L.M. Ball. A 2-Iminohydantoin from the oxidation of guanine. Chem. Res. Toxicol, 19:506-510, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16608161) Exit NIEHS
  26. Kuhn, J., P. Hoerth, S.T. Hoehn, T. Preckel, K.B. Tomer. Proteomics study of anthrax lethal toxin-treated murine macrophages. Electrophoresis, 27:1584-1597, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16609935) Exit NIEHS
  27. Vitorino, R., S. Guedes, R. Ferreira, M.J.C. Lobo, J. Duarte, A.J. Ferrer-Correia, K. Tomer, P. Domingues, F.L. Amado. 2D electrophoresis study of in vitro pellicle formation and dental caries susceptibility. Eur. J. Oral Sci., 114(2):147-153, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16630307) Exit NIEHS
  28. Sharp, J.S., S. Nelson, D. Brown, K.B. Tomer. Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS. Virol., 348: 216-223, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16443253) Exit NIEHS
  29. Cao, H., L.J. Deterding, J.D. Venable, E.A. Kennington, J.R. Yates, III, K.B. Tomer, P.J. Blackshear. Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem. J., 394(1): 285-297, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16262601) Exit NIEHS
  30. Fostel, J., D. Choi, C. Zwick, N. Morrison, A. Rashid, A. Hasan, W. Bao, A. Richard, W. Tong, P.R. Bushel, R. Brown, M. Bruno, M.L. Cunningham, D. Dix, W. Eastin, C. Frade, A. Garcia, A. Heinloth, R. Irwin, J. Madenspacher, B.A. Merrick, T. Papoian, R. Paules, P. Rocca-Serra, A.-S. Sansone, J. Stevens, K. Tomer, C. Yang, M. Waters. Chemical Effects in Biological Systems – Data Dictionary (CEBS-DD): A compendium of terms for the capture and integration of biological study design description, conventional phenotypes and ‘omics’ data. Toxicol. Sci., 88(2):585-601, (Dec.)2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16150882) Exit NIEHS
  31. De Morais-Guedes, S., R. Vitorino, R. Domingues, K. Tomer, A.J. Ferrer-Correia, F. Amado, P. Domingues. Proteomics of immune-challenged Drosophila melanogaster larvae heamolymph. Biochem. Biophys. Res. Commun., 328:106-115, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15670757) Exit NIEHS
  32. Hartman, T.J., D.J. Baer, L.B. Graham, W.I. Stone, E.W. Gunter, C.E. Parker, P.S. Albert, J.F. Dorgan, B.A. Clevidence, W.S. Campbell, K.B. Tomer, J.T. Judd, P.R. Taylor. Moderate alcohol consumption and levels of antioxidant vitamins and isoprostanes in postmenopausal women. Eur. J. Clin. Nutrition, 59:161-8, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15367922) Exit NIEHS
  33. M.B. Kadiiska, B.C. Gladen, D.B. Baird, D. Germolec, L.B. Graham, C.E. Parker, A. Nyska, J.T. Wachsman, B.N. Ames, S. Basu, N. Brot, G.A. Fitzgerald, R.A. Floyd, M. George, J.W. Heinecke, G.H. Hatch, K. Hensley, J.A. Lawson, L.J. Marnett, J.D. Morrow, D.M. Murray, J. Plastaras, L.J. Roberts, J. Rokach, M.K. Shigenaga, R.S. Sohal, J. Sun, R.R. Tice, D.H. Van Thiel, D. Wellner, P.B. Walter, K.B. Tomer, R.P. Mason, J.C. Barrett. Biomarkers of Oxidative Stress Study. II. Are Oxidation Products of Lipids, Proteins and DNA Markers in CCl4 Poisoning? Free Rad. Biol. Med., 38:698-710, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721980) Exit NIEHS
  34. Kadiiska, M.B., B.C. Gladen, D.B. Baird, L.B. Graham, C.E. Parker, A.B.N. Ames, S. Basu, G.A. Fitzgerald, J.A. Lawson, L.J. Marnett, D.M. Murray, J. Plastaras, L.J. Roberts, M.K. Shigenaga, J. Sun, P.B. Walter, K.B. Tomer, J.C. Barrett and R.P. Mason. Biomarkers of Oxidative Stress Study III. Effect of the Non-Steroidal Anti-inflammatory Agents Indomethacin and Meclofenamic acid on Measurements of Oxidative Products of Lipids in CCl4 Poisoning. Free Rad. Biol. Med., 38:711-718, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721981) Exit NIEHS
  35. Sharp, J. S., K.B. Tomer. Formation of b(n-1) + OH + H ions by solution-phase chemistry. J. Amer. Soc. Mass Spectrom., 16:607-621, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15862763) Exit NIEHS
  36. Titus, M.A., M.J. Schell, F.B. Lih, K.B. Tomer, J.L. Mohler. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin. Cancer Res., 11(13):4653-7, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16000557) Exit NIEHS
  37. Rhodin N.R., J.M. Cutalo, K.B. Tomer, W.P. McArthur, L.J. Brady. Characterization of the Streptococcus mutans P1 epitope recognized by immunomodulatory monoclonal antibody 6-11A. Infect. Immun., 72:4680-8, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15271929) Exit NIEHS
  38. Detweiler, C.D., O.M. Lardinois, L.J. Deterding, P.O. de Montellano, K. B. Tomer, R.P. Mason. Identification of the Myoglobin Tyrosyl Radical by Immuno-spin Trapping and its Dimerization. Free Radi. Biol. Med., 38:969-976, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15749393) Exit NIEHS
  39. Cutalo, J.M., L.J. Deterding, K.B. Tomer. Characterization of Glycopeptides From HIV-ISF2 gp120 by Liquid Chromatography Mass Spectrometry. J. Amer. Soc. Mass Spectrom., 15(11):1545-1555, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15519221) Exit NIEHS
  40. Williams, J., K.B. Tomer. Disposable Chromatography for a High-throughput Nano-ESI/MS and Nano-ESI/MS-MS Platform. J. Amer. Soc. Mass Spectrom., 15:1333-1340, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15337514) Exit NIEHS
  41. Vitorino, R., M.J.C. Lobo, A.J. Ferrer-Correia, K.B. Tomer, P.M. Domingues, F.M.L. Amado. In vitro hydroxyapatite adsorbed salivary proteins. Biochem. Biophys. Res. Commun., 320:342-346, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15219832) Exit NIEHS
  42. Xirasagar, S., S. Gustafson, A. Merrick, K.B. Tomer, S. Stasiewicz, D.D. Chan, K.J. Yost III, J.R. Yates III, S. Sumner, N. Xiao, M.D. Waters. CEBS Object Model for Systems Biology Data, SysBio-OM. Bioinformatics, 20:2004-2015, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15044233) Exit NIEHS
  43. Deterding, L.J., D.C. Ramirez, J.R. Dubin, R.P. Mason, and K.B. Tomer. Identification of free radicals on hemoglobin from its self-peroxidation using mass spectrometry and immuno-spin trapping: observation of a histidinyl radical. J. Biol. Chem., 279:11600-11607, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14699100) Exit NIEHS
  44. Vitorino R, M.J.C. Lobo, P. Domingues, A.J. Correia, K.B. Tomer, F.M.L. Amado. Analysis of Salivary peptides using HPLC-Electrospray Mass Spectrometry. Biomedical Chromatography 18(8):570-5, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15386514) Exit NIEHS
  45. Vitorino, R., M.J.C. Lobo, A.J. Ferrer-Correia, J.R. Dubin, K.B. Tomer, P.M. Domingues, F.M.L. Amado. Identification of human whole saliva protein components using proteomics. Proteomics, 4(4):1109-1115, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15048992) Exit NIEHS
  46. De Morais-Guedes, S., R. Vitorino, K. Tomer, R.M. Domingues, A.J. Ferrer-Correia, F. Amado, P. Domingues. Drosophila melanogaster larval heamolymph protein mapping. Biochem. Biophys. Res. Commun., 312:545-554, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14680800) Exit NIEHS
  47. Deterding, L.J., M. Khaledi, and K.B. Tomer. Effect of nonaqueous buffer modifiers on the capillary electrophoresis/mass spectrometry analysis of peptides. J. Capillary Electrophoresis, 8(1/2):11-18, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12757123) Exit NIEHS
  48. Hall, M.C., P. Shcherbakova, J.M. Fortune, C.H. Borchers, J.M. Dial, K.B. Tomer, T.A. Kunkel. DNA binding by yeast Mlh1 and Pms1: Implications for DNA mismatch repair. Nucleic Acids Res. 31(8):2025-2034, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12682353) Exit NIEHS
  49. Iida, M., C.H. Anna, J. Hartis, M. Bruno, B. Wetmore, J.R. Dubin, S. Sieber, L. Bennett, M.L. Cunningham, R.S. Paules, K.B. Tomer, C.D. Houle, B.A. Merrick, R.C. Sills, T.R. Devereux. Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens Oxazepam and Wyeth-14,643. Carcinogenesis 24:757-770, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12727805) Exit NIEHS
  50. Deterding, L.J., M. Khaledi, and K.B. Tomer. Effect of nonaqueous buffer modifiers on the capillary electrophoresis/mass spectrometry analysis of peptides. J. Capillary Electrophoresis, 8(1/2):11-18, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12757123) Exit NIEHS
  51. Bruno, M.E., C.H. Borchers, J.M. Dial, N.J. Walker, J.E. Hartis, B.E. Wetmore, J.C. Barrett, K.B. Tomer, and B.A. Merrick. Effects of TCDD upon IkB and IKK subunits localized in microsomes by proteomics. Arch. Biochem. Biophys., 406(2):153-164, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12361703) Exit NIEHS
  52. Chen, Y.-R., L.J. Deterding, B.E. Sturgeon, K.B. Tomer, and R.P. Mason. Protein oxidation of cytochrome c by reactive halogen species enhances its peroxidase activity. J. Biol. Chem., 77:29781-29791, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12050149) Exit NIEHS
  53. Qian, S.Y., K.B. Tomer, G. Yue, Q. Guo, M.B. Kadiiska, and R.P. Mason. Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: Identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry. Free Radical Biology & Medicine, 33:998-1009, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12361809) Exit NIEHS
  54. Detweiler, C.D., L.J. Deterding, K.B. Tomer, C.F. Chignell, D. Germolec, and R.P. Mason. Immunological identification of the heart myoglobin radical specifically formed by hydrogen peroxide. Free Radical Biology and Medicine, 33(3):364-369, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12126758) Exit NIEHS
  55. Qian, S.Y., Y.-R. Chen, L.J. Deterding, Y.C. Fann, C.F. Chignell, K.B. Tomer, and R.P. Mason. Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: Characterization by ESR spin-trapping, high performance liquid chromatography, and mass spectrometry. Biochem. J., 363(2):281-288, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11931655) Exit NIEHS
  56. Deterding, L.J., J.M. Cutalo, M. Khaledi, and K.B. Tomer. Separation and characterization of human high density apolipoproteins using nonaqueous modifiers in capillary electrophoresis/mass spectrometry. Electrophoresis, 23(14):2296-2305, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12210236) Exit NIEHS
  57. Wine, R.N., C.E. Parker, J.M. Dial, K.B. Tomer, and C.H. Borchers. Identification of components of protein complexes using a fluorescent photo-crosslinker and mass spectrometry. Anal. Chem., 74(9):1939-1945, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12033289) Exit NIEHS
  58. Hager-Braun, C., and K.B. Tomer. Characterization of the tertiary structure of soluble CD4 bound to glycosylated full-length HIV gp120 by chemical modification of arginine residues and mass spectrometric analysis. Biochem., 41:1759-1766, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11827520) Exit NIEHS
  59. Guo, Q., J.T. Corbett, G. Yue, Y.C. Fann, S.Y. Qian, K.B. Tomer, and R.P. Mason. Electron spin resonance investigation of semiquinone radicals formed from the reaction of ubiquinone 0 with human oxyhemoglobin. J. Biol. Chem. 277(8):6104-6110, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11748217) Exit NIEHS
  60. Parker, C.E., and K.B. Tomer. MALDI/MS-based epitope mapping of antigens bound to immobilized antibodies. Mol. Biotechnol. 20(1):49-62, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11876299) Exit NIEHS
  61. Parker, C.E., L.J. Deterding, C. Hager-Braun, J.M. Binley, N. Schuelke, H. Katinger, J.P. Moore, and K.B. Tomer. Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody, 2F5. J. Virol., 75:10906-10911, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11602730) Exit NIEHS
  62. Banks, G.C., L.J. Deterding, K.B. Tomer, and T.K. Archer. Hormone mediated dephosphorylation of specific histone H1 isoforms. J. Biol Chem., 276:36467-36473, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11479299) Exit NIEHS
  63. Peter, J.F., and K.B. Tomer. A general strategy for epitope mapping by direct MALDI-TOF mass spectrometry using secondary antibodies and crosslinking. Anal. Chem., 73:4012-4019, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11534730) Exit NIEHS
  64. Parker, C.E., L.B. Graham, M.-N. Nguyen, B.C. Gladen, M. Kadiiska, J.C. Barrett, and K.B. Tomer. An improved GC/MS-based procedure for the quantitation of the isoprostane 15-F2t IsoP in rat plasma. Molecular Biotechnology, 18:105-118, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11471453) Exit NIEHS
  65. Petrotchenko, E.V., Pedersen, L.C., Borchers, C.H., Tomer, K.B., and Negishi, M. The dimerization motif of cytosolic sulfotransferases. FEBS Lett., 490:39-43, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11172807) Exit NIEHS
  66. Tomer, K.B. Separations Combined With Mass Spectrometry. Chem. Rev., 101:297 328, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11712249) Exit NIEHS
  67. Merrick, B.A., Zhou, W., Martin, K.J., Jeyarajah S., Parker, C.E., Selkirk, J.K., Tomer, K.B., and Borchers, C.H. Site-specific phosphorylation of human p53 protein determined by mass spectrometry. Biochem., 40:4053-4066, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11300786) Exit NIEHS
  68. Deterding, L.J., Kast, J., Przybylski, M., and Tomer, K.B. Molecular characterization of a tetramolecular complex between dsDNA and a DNA-binding leucine zipper peptide dimer by mass spectrometry. Bioconj. Chem., 11(3): 335-344, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10821649) Exit NIEHS
  69. Zhou, W., Tomer, K.B., and Khaledi, M.G. Evaluation of the binding between potential anti-HIV DNA based drugs and viral envelope glycoprotein gp120 by capillary electrophoresis with laser-induced fluorescence detection. Anal. Biochem., 284(2): 334-341, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10964417) Exit NIEHS
  70. Zhu, X., C. Borchers, R.J. Bienstock, and K.B. Tomer. Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells. Biochem., 39:11194-11204, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10985765) Exit NIEHS
  71. Parker, C.E., and K.B. Tomer. Epitope mapping by a combination of epitope excision and MALDI/MS. In: Chapman, J., (ed.): Protein and peptide analysis: advances in the use of mass spectrometry, vol. 146 of Methods in Molecular Biology, Humana, Totowa, NJ, 185-201, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10948503) Exit NIEHS
  72. Zhou, W., B.A. Merrick, M.G. Khaledi, and K.B. Tomer. Detection and sequencing of phosphopeptides affinity bound to immobilized metal ion beads by matrix-assisted laser desorption/ionization mass spectrometry. J. Amer. Soc. Mass Spectrom., 11:273 282, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10757163) Exit NIEHS
  73. Deterding, L.J., R., Prasad, G.P. Mullen, S.H. Wilson, and K.B Tomer. Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase by mass spectrometry. J. Biol. Chem., 275(14):10463-10471, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10744736) Exit NIEHS
  74. Chen, Y.-R., L.J. Deterding, K.B. Tomer, and R.P. Mason. The nature of the inhibition of horseradish peroxidase and mitochondrial cytochrome c oxidase by cyanyl radical. Biochem., 39(15): 4415-4422, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10757991) Exit NIEHS
  75. Hochleitner, E.O., C. Borchers, C. Parker, R.J. Bienstock, and K.B. Tomer. Characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) core protein p24 by epitope excision and differential chemical modification followed by mass spectrometric peptide mapping analysis. Protein Sci., 9: 487-496, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10752610) Exit NIEHS
  76. Borchers, C., J.F. Peter, M.C. Hall, T.A. Kunkel, and K.B. Tomer. Identification of In Gel Digested Proteins by Complementary Peptide-Mass Fingerprinting and Tandem Mass Spectrometry Data Obtained on an Electrospray Ionization Quadrupole Time-of Flight Mass Spectrometer. Anal. Chem., 72:1163-1168, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10740854) Exit NIEHS
  77. Hochleitner, E.O., M.K. Gorny, S. Zolla-Pazner, and K.B. Tomer. Mass spectrometric characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) envelope protein HIV-gp120 recognized by the human monoclonal antibody 1331A. J. Immunol., 164(8): 4156-4161, 2000.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10754311) Exit NIEHS

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