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| PLEASE NOTE: This is a draft agenda. |
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| February 8, 2007 |
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| 7:00 – 8:00 a.m. |
Registration and Continental Breakfast |
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| 8:00 – 8:15 a.m. |
Welcome and Opening Remarks
Robert A. Star, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
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| 8:15 – 9:15 a.m. |
Keynote Address:
Kidney Development and Repair: Translational Outlook
Joseph V. Bonventre, M.D., Ph.D.
Brigham and Women’s Hospital |
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| Session I |
Renal Progenitors and Lineage Progression
Moderator:
Gregory R. Dressler, Ph.D. |
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| 9:15 – 9:40 a.m. |
Factors Which Regulate Formation of the Intermediate Mesoderm
Thomas M. Schultheiss, M.D., Ph.D.
Beth Israel Deaconess Medical Center and Harvard Medical School |
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| 9:40 – 10:05 a.m. |
Specification of Proximal Versus Distal Tubule
Raphael Kopan, Ph.D.
Washington University |
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| 10:05– 10:20 a.m. |
BREAK |
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| 10:20 – 10:45 a.m. |
Cell Lineages in Kidney during Development and Repair
Peter Igarashi, M.D.
University of Texas Southwestern Medical Center |
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| 10:45 – 11:10 a.m. |
Tail Bud-Derived Mesenchyme Patterns the Urinary Tract
Doris Herzlinger, Ph.D.
Weill Cornell Medical College, Cornell University |
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| 11:10 – 11:35 a.m. |
Linking Renal Epithelial Cell Specification to Epigenetic
Imprinting Mechanisms
Gregory R. Dressler, Ph.D.
University of Michigan |
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| 11:35 – 1:00 p.m. |
LUNCH (on your own) |
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| Session II |
Disease, Development, and Repair
Moderator: Lloyd
Cantley, M.D. |
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| 1:00 – 1:25 p.m. |
Regulation of Epithelial Morphology during Tubule Repair
Lloyd Cantley, M.D.
Yale University School of Medicine |
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| 1:25 – 1:50 p.m. |
Epithelial-Mesenchymal Transitions (EMT) in Renal Fibrosis
Eric G. Neilson, M.D.
Vanderbilt University School of Medicine |
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| 1:50 – 2:15 p.m. |
Iron Transport in the Kidney
Jonathan M. Barasch, M.D., Ph.D.
Columbia University |
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| 2:15 – 2:40 p.m. |
Cholesterol Accumulation: Implications for Cell Injury and the
Post Injury Cytoresistant State
Richard A. Zager, M.D.
University of Washington |
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| 2:40 – 3:05 p.m. |
Piecing Together the Renal Fibrosis Puzzle
Allison A. Eddy, M.D.
Children’s Hospital and Regional Medical Center and the University of
Washington |
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| 3:05 – 3:30 p.m. |
Regulation of mTOR and STAT6 by Polycystin-1: Is Polycystic
Kidney
Disease a Case of Futile Repair?
Thomas Weimbs, Ph.D.
University of California at Santa Barbara |
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| 3:30 – 4:00 p.m. |
BREAK |
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| 4:00 – 6:30 p.m. |
Poster Session |
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| Back to Top |
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| February 9, 2007 |
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| 7:00 – 8:00 a.m. |
Continental Breakfast |
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| 8:00 – 9:00 a.m. |
Keynote Address:
Developmental Recapitulation by Embryonic Stem Cells
Douglas Melton, Ph.D.
Harvard University |
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| Session III |
Kidney Cellular Niches
Moderator: Melissa Little, Ph.D. |
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| 9:00 – 9:25 a.m. |
Defining Progenitor Populations, Niches, and Potential Repair
Factors Via Comprehensive Temporospatial Gene Expression Analysis of
Renal Development and Disease
Melissa Little, Ph.D.
The University of Queensland, Brisbane, Australia |
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| 9:25 – 9:50 a.m. |
Cellular Crosstalk Required for Glomerular Development
Susan Quaggin, M.D.
University of Toronto, Ontario, Canada |
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| 9:50 –10:15 a.m. |
Cell/Extracellular Matrix Interactions in the Kidney
Jeffrey H. Miner, Ph.D.
Washington University School of Medicine |
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| 10:15 – 10:45 a.m. |
BREAK |
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| 10:45 – 11:10 a.m. |
Stem Cells and Their Niche in the Adult Kidney
Qais Al-Awqati, M.B., Ch.B.
Columbia University School of Physicians and Surgeons |
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| 11:10 – 11:35 a.m. |
Role of FGFs in Regulating Branching and Nephron Number
Carl Bates, M.D.
Columbus Children’s Research Institute |
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| 11:35 – 12:00 noon |
From Precursor to Product: Nephrogenesis in Mammalian Kidney
Development
Andrew McMahon, Dr.P.H.
Harvard University |
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| 12:00 – 1:30 p.m. |
LUNCH
(on your own) |
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| 1:30 – 1:45 p.m. |
Hot Topic Speaker #1 –
WTIP Is Required for Normal Development of the Zebrafish Pronephros
Tomoko Obara, Ph.D.
MetroHealth Medical Center, Case Western Reserve University |
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| 1:45 – 2:00 p.m. |
Hot Topic Speaker #2 –
Four-Dimensional Imaging of Renal Vascularization in Living Mouse
Embryos
Deborah Hyink, Ph.D.
Mount Sinai School of Medicine |
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| 2:00 – 2:15 p.m. |
Hot Topic Speaker #3 –
Isolation and Expansion of Resident Murine Kidney Stem Cells to
Accelerate Recovery in Damaged Kidneys
Patricia Agreda
Johns Hopkins University School of Medicine |
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| Session IV |
Looking Forward to Translation
Moderator: Joseph V.
Bonventre, M.D., Ph.D. |
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| 2:15 – 2:40 p.m. |
Tissue Engineering: Considerations and Uses
Linda G. Griffith, Ph.D.
Massachusetts Institute of Technology |
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| 2:40 – 3:05 p.m. |
Directed Tissue Self-Assembly: How to Print Kidney?
Vladimir A. Mironov, M.D., Ph.D.
Medical University of South Carolina |
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| 3:05 – 3:30 p.m. |
Scar Free Healing: From Accidental Discovery to Potential Human
Pharmaceuticals
Mark W.J. Ferguson, Ph.D., FDS, FFD, F.Med.Sci., C.B.E.
University of Manchester, Manchester, England |
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| 3:30 – 3:45 p.m. |
BREAK |
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| 3:45 – 5:00 p.m. |
Panel Discussion: What are scientific requirements for development of renal cell therapies? How should developmental and injury/repair studies inform each other? In what ways might tissue engineered models illuminate disease processes? Are tissue engineered/cell therapies feasible for the kidney? |
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| 5:00 p.m. |
Adjourn the Meeting |
