|
![Working Together To Manage Diabetes: A guide for Pharmacy, Podiatry, Optometry, and Dental professionals](images/header.gif) |
![](https://webarchive.library.unt.edu/eot2008/20090113205158im_/http://www.ndep.nih.gov/images/spacer.gif) |
Drug Table Supplement Contents
SECTION B Medications to Lower High Blood Pressure*
Category |
Generic Name |
Brand NameTM |
Minimum Daily Dose |
Maximum Daily Dose |
Special Considerations for class of drugs |
Angiotensinconverting
enzyme
(ACE) inhibitors |
benazepril |
Lotensin™ |
10 mg QD |
40 mg QD or divided |
May cause cough.
May increase potassium concentrations.
Do not use potassium or salt substitutes without
consulting physician.
Do not use if pregnant or if trying to conceive.
Caution if creatinine >1.5. |
captopril |
Capoten™ |
25 mg divided dose |
100 mg divided dose |
enalapril |
Vasotec™ |
5 mg QD |
40 mg QD or divided |
fosinopril |
Monopril™ |
10 mg QD |
40 mg QD or divided |
lisinopril |
Prinivil, Zestril™ |
10 mg QD |
40 mg QD |
moexipril |
Univasc™ |
7.5 mg QD |
30 mg QD or divided |
perindopril |
Aceon™ |
4 mg QD |
8 mg QD |
quinapril |
Accupril™ |
10 mg QD |
80 mg QD or divided |
ramipril |
Altace™ |
2.5 mg QD |
20 mg QD or divided |
Angiotensin II
receptor blockers |
trandolapril |
Mavik™ |
1 mg QD |
4 mg QD |
May cause dizziness and upset stomach.
Do not use potassium or salt substitutes without
consulting physician.
Do not use if pregnant or if trying to conceive.
Caution if creatinine >1.5. |
candesartan |
Atacand™ |
8 mg QD |
32 mg QD or divided |
eprosartan |
Teveten™ |
400 mg QD |
800 mg QD or divided |
irbesartan |
Avapro™ |
150 mg QD |
300 mg QD |
losartan |
Cozaar™ |
25 mg QD |
100 mg QD or divided |
olmesartan |
Benicar™ |
20 mg QD |
40 mg QD |
telmisartan |
Micardis™ |
20 mg QD |
80 mg QD |
valsartan |
Diovan™ |
80 mg QD |
320 mg QD |
Calcium channel
blockers |
amlodipine |
Norvasc™ |
2.5 mg QD |
10 mg QD |
May cause constipation, dizziness, upset stomach,
and flushing.
Call physician for shortness of breath, unusual heartbeat,
or swelling of feet or hands. |
diltiazem |
Cardizem LA™ |
120 mg QD |
540 mg QD |
diltiazem |
Cardizem CD™ |
180 mg QD |
420 mg QD |
diltiazem |
Dilacor XR™* |
180 mg QD |
420 mg QD |
diltiazem |
Tiazac™ |
180 mg QD |
420 mg QD |
felodipine |
Plendil™* |
2.5 mg QD |
20 mg QD |
isradipine |
DynaCircCR™* |
2.5 mg QD |
10 mg QD |
nicardipine |
Cardene SR™* |
60mg in divided dose |
120 mg divided dose |
nifedipine |
Adalat CC™* |
30 mg QD |
60 mg QD |
nifedipine |
Procardia XL™* |
30 mg QD |
60 mg QD |
nisoldipine |
Sular™* |
10 mg QD |
40 mg QD |
verapamil |
Calan™ |
80 mg QD in divided dose |
320 mg divided dose |
verapamil |
Calan SR ™ |
120 mg QD |
480 mg divided dose |
verapamil |
Covera HS™* |
120 mg QD |
360 mg QD |
verapamil |
Isoptin™ |
80 mg QD in divided dose |
320 mg divided dose |
verapamil |
Isoptin SR™* |
120 mg QD |
480 mg QD or divided |
verapamil |
Verelan™ |
80 mg QD in divided dose |
320 mg divided dose |
verapamil |
Verelan PM™ |
120 mg QD |
360 mg QD |
Thiazides and
related diuretics |
bedroflumethiazide |
Naturetin™ |
2.5 mg QD |
20 mg QD |
May increase blood glucose concentrations.
Take in morning to minimize diuretic effect at night.
May cause low potassium, need to monitor level. |
chlorothiazide |
Diuril™ |
125 mg QD |
500 mg QD or divided |
chlorthalidone |
Hygroton™ |
12.5 mg QD |
25 mg QD |
hydrochlorothiazide |
HydroDIURIL™ |
12.5 mg QD |
50 mg QD or divided |
hydrochlorothiazide |
Microzide™ |
12.5 mg QD |
50 mg QD or divided |
indapamide |
Lozol™ |
1.25 mg QD |
2.5 mg QD |
methyclothiazide |
Enduron™ |
2.5 mg QD |
5 mg QD |
metolazone |
Mykrox™ |
0.5 mg QD |
1.0 mg QD |
metolazone |
Zaroxolyn™ |
2.5 mg QD |
5 mg QD |
Loop diuretics |
bumetanide |
Bumex™ |
0.5 mg QD |
2 mg QD or divided |
May cause low potassium.
Need blood test to monitor level.
(Parenteral drug available) May cause
photosensitivity:sunscreen recommended. |
ethacrynic acid |
Edecrin™ |
25 mg QD |
200 mg divided dose |
furosemide |
Lasix™ |
20 mg QD |
80 mg QD or divided |
torsemide |
Demadex™ |
2.5 mg QD |
10 mg QD |
Potassium-sparing
diuretics |
amiloride |
Midamor™ |
5 mg QD |
10 mg QD |
Do not use potassium or salt substitutes without consulting physician. Need to monitor potassium level. |
triamterene |
Dyrenium™ |
50 mg QD or divided |
100 mg divided dose |
Aldosterone receptor
blockers |
eplerenone |
Inspra™ |
50 mg QD |
100 mg divided dose |
spironolactone |
Aldactone™ |
25 mg QD |
50 mg divided dose |
ß-blockers |
acebutolol |
Sectral™ |
200 mg QD |
800 mg divided dose |
Intrinsic sympathomimetic activity.
May alter blood glucose, may mask signs of low blood.
Call physician for slow heart rate (<60), confusion,
or swelling of feet or legs.
Can cause claudication.
Do not discontinue abruptly. |
atenolol |
Tenormin™ |
25 mg QD |
100 mg QD |
betaxolol |
Kerlone™ |
5 mg QD |
20 mg QD |
bisoprolol |
Zebeta™ |
2.5 mg QD |
10 mg QD |
carteolol |
Cartol™ |
2.5 mg QD |
10 mg QD |
metoprolol |
Lopressor™ |
50 mg QD |
100 mg QD or divided |
metoprolol |
Toprol XL™* |
50 mg QD |
100 mg QD |
nadolol |
Corgard™ |
40 mg QD |
120 mg QD |
penbutolol |
Levatol™ |
10 mg QD |
40 mg QD |
pindolol |
Visken™ |
10 mg in divided dose |
40 mg divided dose |
propranolol |
Inderal™ |
40 mg divided dose |
160 mg divided dose |
propranolol |
Inderal LA™* |
60 mg QD |
180 mg QD |
timolol |
Blocadren™ |
20 mg divided dose |
40 mg divided dose |
α-blockers |
doxazosin |
Cardura™ |
1 mg QD |
16 mg QD |
To prevent dizziness, avoid standing up suddenly, especially with the first few doses. |
prazosin |
Minipress™ |
2 mg in divided dose |
20 mg divided dose |
terazosin |
Hytrin™ |
1 mg QD |
20 mg QD |
Combined α-and ß-blockers |
carvedilol |
Coreg™ |
12.5 mg divided dose |
50 mg divided dose |
May mask signs of low blood glucose levels.
Take with food to avoid stomach upset. |
labetalol |
Normodyne™ |
200 mg divided dose |
800 mg divided dose |
labetalol |
Trandate™ |
200 mg divided dose |
800 mg divided dose |
Direct vasodilators |
hydralazine |
Apresoline™ |
25 mg QD |
100 mg divided dose |
May cause headaches, fluid retention, or fast heart rate. |
midoxidil |
Loniten™ |
2.5 mg QD |
80 mg divided dose |
Central a-agonists |
clonidine |
Catapres™ |
0.1 mg QD |
0.8 mg divided dose |
Do not discontinue drug suddenly without consulting physician. |
clonidine |
Catapres TTS™* (patch) |
0.1 mg Q week |
0.3 mg Q week |
methyldopa |
Aldomet™ |
250 mg divided dose |
1,000 mg divided dose |
guanfacine |
Tenex™ |
0.5 mg QD |
2 mg QD |
Peripheral
Anti-adrenergics |
guanadrel |
Hylorel™ |
10 mg in divided dose |
75 mg divided dose |
May cause dizziness, nasal congestion, and depression. |
guanethidine |
Ismelin™ |
10 mg QD |
50 mg QD |
resperine |
|
0.1 mg divided dose |
0.25 mg divided dose |
* Agents in a class of medicines share mechanisms of action, require similar precautions and generally have similar side effects.
CC= extended release XL=extended release SR=sustained release CR=controlled release CD=extended release XR=extended release PM=extended release, controlled onset LA = long acting
HS=extended release, controlled onset Dosages based on JNC7 usual dose range.
Note: There are many combination medications for the control of blood pressure. The indications and caveats are the same for each individual component. |
For all anti-hypertensives:
- Ask pharmacist before using OTC products.
- Monitor blood pressure regularly.
- To prevent dizziness, advise patient to stand up slowly. If dizziness persists, refer to health care provider.
Information about high blood pressure can be found at the following Web sites:
Health care professionals: www.nhlbi.nih.gov/health/prof/heart/index.htm
Information for people with diabetes: www.nhlbi.nih.gov/hbp
Drugs used to treat high blood pressure: www.nhlbi.nih.gov/guidelines/hypertension/express.pdf**
**PDF files require the free
Adobe Acrobat Reader application for viewing.
NDEP-54-S
March 2007 |
![](https://webarchive.library.unt.edu/eot2008/20090113205158im_/http://www.ndep.nih.gov/images/spacer.gif) |
|
|
next > |
|
|
|
|
![NDEP logo](https://webarchive.library.unt.edu/eot2008/20090113205158im_/http://www.ndep.nih.gov/images/logo_NDEP_med.gif)
National Diabetes Education Program (NDEP) http://ndep.nih.gov
NIDDK, National Institutes of Health, Bethesda, MD
A Joint Initiative of the National Institutes of Health and the
Centers for Disease Control and Prevention |
|
|
|
Includes information about managing the ABCs of Diabetes. Also features information for people with diabetes who are eligible for Medicare benefits.
Learn how to prevent or delay type 2 diabetes through small steps.
|