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FY 2008 Bench-to-Bedside Funded Projects
GENERAL CATEGORY:
Teams
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Projects
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Investigators
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NCI
NIAID
Ludwig Institute for Cancer Research
Weill Medical College Cornell |
Targeting cancer-testis gene expression for lung cancer therapy
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D. Schrump, MD, NCI; V. Lobanenkov, PhD, NIAID; L. Old, MD, Ludwig Institute for Cancer Research; and N. Altorki, MD, Weill Med College, Cornell |
NINR
U of MD |
Molecular mechanisms of glial cell modulation of chemotherapy-induced painful peripheral neuropathy
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X. Wang, MD, PhD, NINR; S. Dorsey, RN, PhD, and C. Renn, RN, PhD, U of MD |
AIDS CATEGORY:
Teams
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Project
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Investigators
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NCI
University of California, San Diego |
New strategies to decrease and eradicate HIV-1 reservoirs
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F. Maldarelli, MD, PhD, NCI; E. Reid, MD, UCSD |
NICHD
Case Western Reserve |
HIV-1 suppression by Acyclovir in patients coinfected with human herpesviruses from basic mechanism to clinical application
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L. Margolis, PhD, NICHD; M. Lederman, MD, Case Western |
NIAID
NHLBI, Children’s National Medical Center
NC |
Non-invasive cardiac 3T MRI for evaluation of premature coronary artery disease and myocardial dysfunction in adolescents and young adults with HIV acquired in infancy and childhood
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C. Hadigan, MD, MPH, NIAID; A. Gharib, MD, NHLBI; R. Cross, MD, MS, CNMC; S. Clauss, MD, CNMC |
AIDS/MINORITY HEALTH CATEGORY:
Teams
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Project
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Investigators
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NIAID
Johns Hopkins University
Uganda (Makere Medical School, Mulago Hospital) |
Hepatitis B and HIV co-infection in Uganda
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T. Quinn, MD and L. Stabinski, MD, MPH, NIAID; C. Thio, MD and G. Kirk, MD, MPH, PhD, JHU |
NCI
FDA
University of Washington |
Development and evaluation of a nanoparticle-based HIV-1 p24 antigen assay for monitoring therapy in resource limited settings
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F. Maldarelli, MD, PhD, NCI; Hewlett, PhD, FDA; L. Frenkel, MD, U of WA |
MINORITY HEALTH & HEALTH DISPARITIES CATEGORY:
Teams
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Project
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Investigators
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NIDDK
University of Michigan
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Toward molecular-marker based management of diabetic nephropathy in Pima Indians
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R. Nelson, MD, PhD, NIDDK; M. Kretzler, MD, U MI |
RARE DISEASES CATEGORY:
Teams
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Project
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Investigators
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NHGRI
University of South Carolina
University of Texas-MD Anderson |
Predicting the response to treatment using gene mutation profiling in metastatic melanoma patients
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Y. Samuels, PhD, NHGRI; P. Buckhaults, PhD, U of SC; P. Hwu, MD, U of TX-MD Anderson
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NHLBI
NIH Clinical Center |
Graft-Versus-Host Disease: novel cellular therapy using selective thawing of umbilical cord blood to obtain an aliquot for ex-vivo natural killer cell expansion and infusion following allogeneic hematopoietic stem cell transplantation
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R. Childs, MD, NHLBI; S. Vasu, MD, CC
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NIH Clinical Center
NHLBI
INOVA Fairfax Hosp |
Evaluation of the platelet transcriptome expression profile in pulmonary arterial hypertension
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R.F. Machado, MD (Clinical /Translational) and N. Raghavachari, PhD, NHLBI (Basic Science); S. Nathan, MD, INOVA |
NHLBI
Harvard
Temple University
NIH Clinical Center |
Characterization of Jak/Stat activation in patients with monosomy 7 and the development of targeted therapy for patients using a Jak2 inhibitor
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E. Sloand, MD and N. Young, MD, NHLBI; J. Groopman, MD, Harvard |
NHLBI
Imperial College, London |
Development of immunotherapeutic strategies to overcome tolerance in leukemia
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A. J. Barrett, MD, NHLBI; K. Rezvani, MD, PhD, Imperial College School of Med
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NIAID
NCI |
Recombinant human IL-& (CYT107) as immunomodulatory therapy for idiopathic CD4 lymphopenia: a phase I/IIA open-label pilot study
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J. Brenchley, PhD and I. Sereti, MD, MHS, NIAID
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WOMEN'S HEALTH CATEGORY:
Teams
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Project
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Investigators
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NHLBI
NCI
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Immunogenicity of quadrivalent human papilloma virus vaccine (HPV Types 6, 11, 16, 18) in recipients of reduced intensity hematologic stem cell transplantation (HSCT)
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Bedside: A. Chenoy, MD, NHLBI and P. Stratton, MD, NICHD
PBench: L. Pinto, MD and L. Wood, MD, NCI |
NICHD
NIDDK
Sackler School of Med, Tel Aviv, Israel |
Histaminergic pathways and energy intake in obese women
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J. Yanovski, MD, PhD, L. Yanoff, MD, and C. Cropp, PharmD, NICHD
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Awards Funded
2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999
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