AGENDA |
| Tuesday, March 24, 2009 (8:00 a.m. – 5:00 p.m.) |
| Welcome and Introduction |
Clinical Overview: Unmet Needs and Challenges
Pankaj J. Pasricha |
Clinical Overview: A Clinical Urologist’s View of Bladder Smooth Muscle Function
Steve Zderic |
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| Session 1: Structure and Contraction Function of Organ Smooth Muscle |
Session Overview
Karnam Murthy |
Myoarchitecture and Organ Function
Ravinder Mittal |
Signal Integration Through Myosin Phosphorylation in Smooth Muscle
James Stull |
Caldesmon and Actin-Based Regulation in Smooth Muscle Cells
C. L. Albert Wang |
Potassium Channels and Smooth Muscle Function
Mark Nelson |
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| Session 2: Non-Contractile Functions of Differentiated Smooth Muscle |
Session Overview
Don Powell |
Prostatic Smooth Muscle/Stromal Cells Normal Physiology and Disease
Karl-Erik Anderson |
Myofibroblasts and Gut Epithelial Proliferation/Stem Cell Niche
Deborah Rubin |
Classic and New Paradigms for Vascular Smooth Muscle Cell Phenotypic Switching
Brian Wamhoff |
Role of Cryptic Smooth Muscle and Myofibroblast Cells as Intestinal Stem Cell Niche
Xin Chen |
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| Session 3: Developmental Origins of Smooth Muscle and Interactions Leading to Differentiation |
Session Overview
Gary Owens |
Role of Hedgehog Signaling in Intestinal Smooth Muscle Development and Maintenance
Deborah Gumucio |
Development, Function, and Plasticity of the Neuromuscular Apparatus in Visceral Smooth Muscles
Kenton Sanders |
What Is the Cellular Origin of the Bladder Trigone?
Cathy Mendelsohn |
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| Wednesday, March 25, 2009 (8:00 a.m. – 4:00 p.m.) |
| Session 4: Effects of Inflammation and Disease on Structure and Function of Smooth Muscle; Potential for Therapy |
Session Overview
Gianrico Farrugia |
Obstruction-Induced Alterations in the Contractile and Regulatory Proteins in the Bladder Wall Smooth Muscle
Sam Chacko |
Gene Plasticity in Smooth Muscle Cells Underlies Motility Dysfunction in a Model of Post Infective Irritable Bowel Syndrome (IBS)
Sushil Sarna |
Immune Regulation of Gut Smooth Muscle Function
Terez Shea-Donohue |
Inflammation and Signaling in the Development of Esophagitis
Piero Biancani |
Regulation of Growth in Normal Intestinal Smooth Muscle and Dysregulation of Growth in the Inflamed Intestine
John Kuemmerle |
Interstitial Cells of Cajar (ICC) and Smooth Muscle in Diabetic Gastroenteropathy
Gianrico Farrugia |
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| Session 5: Regenerative Medicine |
Session Overview
Khalil Bitar |
De Novo Bladder Regeneration In Vivo: Regenerative Physiology/Pharmacology of Detrusor Smooth Muscle
George Christ |
Plasticity of Adult ICC Progenitors: Role in Turnover, Regeneration, and Neoplasia of the Gastrointestinal Musculature
Tamas Ordog |
Bioengineering of the Intestinal Smooth Muscle
James Dunn |
Aging and Bioengineering Gastrointestinal Sphincters
Khalil Bitar |
Material Systems to Engineer Smooth Muscle
David Mooney |
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| Session 6: Future Research Needs and Directions |
Session Overview
George Christ |
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