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Volume 4(4);  April 2008
Special Report
SNPs Meet CNVs in Genome-Wide Association Studies: HGV2007 Meeting Report
Xavier Estivill, Nancy J. Cox, Stephen J. Chanock, Pui-Yan Kwok, Stephen W. Scherer, and Anthony J. Brookes
PLoS Genet. 2008 April; 4(4): e1000068. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000068.
PMCID: PMC2330071
Review
Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis
Michelle M. A. Fernando, Christine R. Stevens, Emily C. Walsh, Philip L. De Jager, Philippe Goyette, Robert M. Plenge, Timothy J. Vyse, and John D. Rioux
PLoS Genet. 2008 April; 4(4): e1000024. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000024.
PMCID: PMC2291482
Research Articles
A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci
Ying Liu, Cynthia Helms, Wilson Liao, Lisa C. Zaba, Shenghui Duan, Jennifer Gardner, Carol Wise, Andrew Miner, M. J. Malloy, Clive R. Pullinger, John P. Kane, Scott Saccone, Jane Worthington, Ian Bruce, Pui–Yan Kwok, Alan Menter, James Krueger, Anne Barton, Nancy L. Saccone, and Anne M. Bowcock
PLoS Genet. 2008 April; 4(4): e1000041. Published online 2008 April 4. doi: 10.1371/journal.pgen.1000041.
PMCID: PMC2274885
Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus
Natalie D. Fedorova, Nora Khaldi, Vinita S. Joardar, Rama Maiti, Paolo Amedeo, Michael J. Anderson, Jonathan Crabtree, Joana C. Silva, Jonathan H. Badger, Ahmed Albarraq, Sam Angiuoli, Howard Bussey, Paul Bowyer, Peter J. Cotty, Paul S. Dyer, Amy Egan, Kevin Galens, Claire M. Fraser-Liggett, Brian J. Haas, Jason M. Inman, Richard Kent, Sebastien Lemieux, Iran Malavazi, Joshua Orvis, Terry Roemer, Catherine M. Ronning, Jaideep P. Sundaram, Granger Sutton, Geoff Turner, J. Craig Venter, Owen R. White, Brett R. Whitty, Phil Youngman, Kenneth H. Wolfe, Gustavo H. Goldman, Jennifer R. Wortman, Bo Jiang, David W. Denning, and William C. Nierman
PLoS Genet. 2008 April; 4(4): e1000046. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000046.
PMCID: PMC2289846
An Increase in Mitochondrial DNA Promotes Nuclear DNA Replication in Yeast
Heidi M. Blank, Chonghua Li, John E. Mueller, Lydia M. Bogomolnaya, Mary Bryk, and Michael Polymenis
PLoS Genet. 2008 April; 4(4): e1000047. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000047.
PMCID: PMC2289842
Evolution and Control of Imprinted FWA Genes in the Genus Arabidopsis
Ryo Fujimoto, Yuki Kinoshita, Akira Kawabe, Tetsu Kinoshita, Kazuya Takashima, Magnus Nordborg, Mikhail E. Nasrallah, Kentaro K. Shimizu, Hiroshi Kudoh, and Tetsuji Kakutani
PLoS Genet. 2008 April; 4(4): e1000048. Published online 2008 April 4. doi: 10.1371/journal.pgen.1000048.
PMCID: PMC2270340
Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait
Juliet Ansel, Hélène Bottin, Camilo Rodriguez-Beltran, Christelle Damon, Muniyandi Nagarajan, Steffen Fehrmann, Jean François, and Gaël Yvert
PLoS Genet. 2008 April; 4(4): e1000049. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000049.
PMCID: PMC2289839
Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements
Weise Chang, Zhengshi Lin, Holger Kulessa, Jean Hebert, Brigid L. M. Hogan, and Doris K. Wu
PLoS Genet. 2008 April; 4(4): e1000050. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000050.
PMCID: PMC2274953
β-Globin LCR and Intron Elements Cooperate and Direct Spatial Reorganization for Gene Therapy
Alla Buzina, Mandy Y. M. Lo, Angela Moffett, Akitsu Hotta, Eden Fussner, Rikki R. Bharadwaj, Peter Pasceri, J. Victor Garcia-Martinez, David P. Bazett-Jones, and James Ellis
PLoS Genet. 2008 April; 4(4): e1000051. Published online 2008 April 18. doi: 10.1371/journal.pgen.1000051.
PMCID: PMC2271131
A Genome-Wide Gene Expression Signature of Environmental Geography in Leukocytes of Moroccan Amazighs
Youssef Idaghdour, John D. Storey, Sami J. Jadallah, and Greg Gibson
PLoS Genet. 2008 April; 4(4): e1000052. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000052.
PMCID: PMC2290968
Global Transcriptome and Deletome Profiles of Yeast Exposed to Transition Metals
Yong Hwan Jin, Paul E. Dunlap, Sandra J. McBride, Hanan Al-Refai, Pierre R. Bushel, and Jonathan H. Freedman
PLoS Genet. 2008 April; 4(4): e1000053. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000053.
PMCID: PMC2278374
Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics
Montserrat Garcia-Closas, Per Hall, Heli Nevanlinna, Karen Pooley, Jonathan Morrison, Douglas A. Richesson, Stig E. Bojesen, Børge G. Nordestgaard, Christen K. Axelsson, Jose I. Arias, Roger L. Milne, Gloria Ribas, Anna González-Neira, Javier Benítez, Pilar Zamora, Hiltrud Brauch, Christina Justenhoven, Ute Hamann, Yon-Dschun Ko, Thomas Bruening, Susanne Haas, Thilo Dörk, Peter Schürmann, Peter Hillemanns, Natalia Bogdanova, Michael Bremer, Johann Hinrich Karstens, Rainer Fagerholm, Kirsimari Aaltonen, Kristiina Aittomäki, Karl von Smitten, Carl Blomqvist, Arto Mannermaa, Matti Uusitupa, Matti Eskelinen, Maria Tengström, Veli-Matti Kosma, Vesa Kataja, Georgia Chenevix-Trench, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing Chen, Australian Ovarian Cancer Management Group, The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Peter Devilee, Christi J. van Asperen, Catharina E. Jacobi, Rob A. E. M. Tollenaar, Petra E.A. Huijts, Jan G. M. Klijn, Jenny Chang-Claude, Silke Kropp, Tracy Slanger, Dieter Flesch-Janys, Elke Mutschelknauss, Ramona Salazar, Shan Wang-Gohrke, Fergus Couch, Ellen L. Goode, Janet E. Olson, Celine Vachon, Zachary S. Fredericksen, Graham G. Giles, Laura Baglietto, Gianluca Severi, John L. Hopper, Dallas R. English, Melissa C. Southey, Christopher A. Haiman, Brian E. Henderson, Laurence N. Kolonel, Loic Le Marchand, Daniel O. Stram, David J. Hunter, Susan E. Hankinson, David G. Cox, Rulla Tamimi, Peter Kraft, Mark E. Sherman, Stephen J. Chanock, Jolanta Lissowska, Louise A. Brinton, Beata Peplonska, Jan G. M. Klijn, Maartje J. Hooning, Han Meijers-Heijboer, J. Margriet Collee, Ans van den Ouweland, Andre G. Uitterlinden, Jianjun Liu, Low Yen Lin, Li Yuqing, Keith Humphreys, Kamila Czene, Angela Cox, Sabapathy P. Balasubramanian, Simon S. Cross, Malcolm W. R. Reed, Fiona Blows, Kristy Driver, Alison Dunning, Jonathan Tyrer, Bruce A. J. Ponder, Suleeporn Sangrajrang, Paul Brennan, James McKay, Fabrice Odefrey, Valerie Gabrieau, Alice Sigurdson, Michele Doody, Jeffrey P. Struewing, Bruce Alexander, Douglas F. Easton, and Paul D. Pharoah
PLoS Genet. 2008 April; 4(4): e1000054. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000054.
PMCID: PMC2291027
Small RNA-Directed Epigenetic Natural Variation in Arabidopsis thaliana
Jixian Zhai, Jun Liu, Bin Liu, Pingchuan Li, Blake C. Meyers, Xuemei Chen, and Xiaofeng Cao
PLoS Genet. 2008 April; 4(4): e1000056. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000056.
PMCID: PMC2289841
Analysis of Chimpanzee History Based on Genome Sequence Alignments
Jennifer L. Caswell, Swapan Mallick, Daniel J. Richter, Julie Neubauer, Christine Schirmer, Sante Gnerre, and David Reich
PLoS Genet. 2008 April; 4(4): e1000057. Published online 2008 April 18. doi: 10.1371/journal.pgen.1000057.
PMCID: PMC2278377
Identification of CIITA Regulated Genetic Module Dedicated for Antigen Presentation
Michal Krawczyk, Queralt Seguín-Estévez, Elisa Leimgruber, Peter Sperisen, Christoph Schmid, Philipp Bucher, and Walter Reith
PLoS Genet. 2008 April; 4(4): e1000058. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000058.
PMCID: PMC2278383
Coordinated Regulation of Intestinal Functions in C. elegans by LIN-35/Rb and SLR-2
Natalia V. Kirienko, John D. K. McEnerney, and David S. Fay
PLoS Genet. 2008 April; 4(4): e1000059. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000059.
PMCID: PMC2312330
Proofreading Activity of DNA Polymerase Pol2 Mediates 3′-End Processing during Nonhomologous End Joining in Yeast
Shun-Fu Tseng, Abram Gabriel, and Shu-Chun Teng
PLoS Genet. 2008 April; 4(4): e1000060. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000060.
PMCID: PMC2312331
Primary Coenzyme Q Deficiency in Pdss2 Mutant Mice Causes Isolated Renal Disease
Min Peng, Marni J. Falk, Volker H. Haase, Rhonda King, Erzsebet Polyak, Mary Selak, Marc Yudkoff, Wayne W. Hancock, Ray Meade, Ryoichi Saiki, Adam L. Lunceford, Catherine F. Clarke, and David L. Gasser
PLoS Genet. 2008 April; 4(4): e1000061. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000061.
PMCID: PMC2291193
Correction
Correction: Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen
Anthony Arnoldo, Jasna Curak, Saranya Kittanakom, Igor Chevelev, Vincent T. Lee, Mehdi Sahebol-Amri, Becky Koscik, Lana Ljuma, Peter J. Roy, Antonio Bedalov, Guri Giaever, Corey Nislow, A. Rod Merrill, Stephen Lory, and Igor Stagljar
PLoS Genet. 2008 April; 4(4): 10.1371/annotation/76d35829-07a2-479f-bbc1-cce6755b6d8c. Published online 2008 April 2. doi: 10.1371/annotation/76d35829-07a2-479f-bbc1-cce6755b6d8c.
PMCID: PMC2637088
Corrects: Anthony Arnoldo, et al. Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen. PLoS Genet. 2008 February; 4(2): e1000005.
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