| | This journal provides immediate access to some articles. Interview Imagine: An Interview with Svante Pääbo Jane Gitschier PMCID: PMC2274957 Research Articles ruvA Mutants That Resolve Holliday Junctions but Do Not Reverse Replication Forks Zeynep Baharoglu, Alison Sylvia Bradley, Marie Le Masson, Irina Tsaneva, and Bénédicte Michel PMCID: PMC2265524 GADD45A Does Not Promote DNA Demethylation Seung-Gi Jin, Cai Guo, and Gerd P. Pfeifer PMCID: PMC2265528 Role of Duplicate Genes in Robustness against Deleterious Human Mutations Tzu-Lin Hsiao and Dennis Vitkup PMCID: PMC2265532 Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region Daan Noordermeer, Miguel R. Branco, Erik Splinter, Petra Klous, Wilfred van IJcken, Sigrid Swagemakers, Manousos Koutsourakis, Peter van der Spek, Ana Pombo, and Wouter de Laat PMCID: PMC2265466 SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome Rea Biacsi, Daman Kumari, and Karen Usdin PMCID: PMC2265469 Functional Characterization of Variations on Regulatory Motifs Lapidot Michal, Orna Mizrahi-Man, and Yitzhak Pilpel PMCID: PMC2265473 Evolution of a Core Gene Network for Skeletogenesis in Chordates Jochen Hecht, Sigmar Stricker, Ulrike Wiecha, Asita Stiege, Georgia Panopoulou, Lars Podsiadlowski, Albert J. Poustka, Christoph Dieterich, Siegfried Ehrich, Julia Suvorova, Stefan Mundlos, and Volkhard Seitz PMCID: PMC2265531 Leukocyte Tyrosine Kinase Functions in Pigment Cell Development Susana S. Lopes, Xueyan Yang, Jeanette Müller, Thomas J. Carney, Anthony R. McAdow, Gerd-Jörg Rauch, Arie S. Jacoby, Laurence D. Hurst, Mariana Delfino-Machín, Pascal Haffter, Robert Geisler, Stephen L. Johnson, Andrew Ward, and Robert N. Kelsh PMCID: PMC2265441 C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging Tjakko J. van Ham, Karen L. Thijssen, Rainer Breitling, Robert M. W. Hofstra, Ronald H. A. Plasterk, and Ellen A. A. Nollen PMCID: PMC2265412 Gene Activation Using FLP Recombinase in C. elegans M. Wayne Davis, J. Jason Morton, Dana Carroll, and Erik M. Jorgensen PMCID: PMC2265415 From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis David L. Aylor and Zhao-Bang Zeng PMCID: PMC2265472 The Mating-Type Chromosome in the Filamentous Ascomycete Neurospora tetrasperma Represents a Model for Early Evolution of Sex Chromosomes Audrius Menkis, David J. Jacobson, Tim Gustafsson, and Hanna Johannesson PMCID: PMC2268244 An Abundant Evolutionarily Conserved CSB-PiggyBac Fusion Protein Expressed in Cockayne Syndrome John C. Newman, Arnold D. Bailey, Hua-Ying Fan, Thomas Pavelitz, and Alan M. Weiner PMCID: PMC2268245 Global Analysis of Genetic, Epigenetic and Transcriptional Polymorphisms in Arabidopsis thaliana Using Whole Genome Tiling Arrays Xu Zhang, Shinhan Shiu, Andrew Cal, and Justin O. Borevitz PMCID: PMC2265482 New Insights into Human Nondisjunction of Chromosome 21 in Oocytes Tiffany Renee Oliver, Eleanor Feingold, Kai Yu, Vivian Cheung, Stuart Tinker, Maneesha Yadav-Shah, Nirupama Masse, and Stephanie L. Sherman PMCID: PMC2265487 Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling Christine T. Ferrara, Ping Wang, Elias Chaibub Neto, Robert D. Stevens, James R. Bain, Brett R. Wenner, Olga R. Ilkayeva, Mark P. Keller, Daniel A. Blasiole, Christina Kendziorski, Brian S. Yandell, Christopher B. Newgard, and Alan D. Attie PMCID: PMC2265422 Transcriptional Profiling Uncovers a Network of Cholesterol-Responsive Atherosclerosis Target Genes Josefin Skogsberg, Jesper Lundström, Alexander Kovacs, Roland Nilsson, Peri Noori, Shohreh Maleki, Marina Köhler, Anders Hamsten, Jesper Tegnér, and Johan Björkegren PMCID: PMC2265530 Geographic Patterns of Genome Admixture in Latin American Mestizos Sijia Wang, Nicolas Ray, Winston Rojas, Maria V. Parra, Gabriel Bedoya, Carla Gallo, Giovanni Poletti, Guido Mazzotti, Kim Hill, Ana M. Hurtado, Beatriz Camrena, Humberto Nicolini, William Klitz, Ramiro Barrantes, Julio A. Molina, Nelson B. Freimer, Maria Cátira Bortolini, Francisco M. Salzano, Maria L. Petzl-Erler, Luiza T. Tsuneto, José E. Dipierri, Emma L. Alfaro, Graciela Bailliet, Nestor O. Bianchi, Elena Llop, Francisco Rothhammer, Laurent Excoffier, and Andrés Ruiz-Linares PMCID: PMC2265669 Fine Mapping of the Psoriasis Susceptibility Locus PSORS1 Supports HLA-C as the Susceptibility Gene in the Han Chinese Population Xing Fan, Sen Yang, Wei Huang, Zhi-Min Wang, Liang-Dan Sun, Yan-Hua Liang, Min Gao, Yue-Qing Ren, Kai-Yue Zhang, Wen-Hui Du, Yu-Jun Shen, Jian-Jun Liu, and Xue-Jun Zhang PMCID: PMC2265413 Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells Lee E. Finlan, Duncan Sproul, Inga Thomson, Shelagh Boyle, Elizabeth Kerr, Paul Perry, Bauke Ylstra, Jonathan R. Chubb, and Wendy A. Bickmore PMCID: PMC2265557 ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over Carrie A. Adelman and John H. J. Petrini PMCID: PMC2267488 Phospholipase C-ε Regulates Epidermal Morphogenesis in Caenorhabditis elegans Rafael P. Vázquez-Manrique, Anikó I. Nagy, James C. Legg, Olivia A. M. Bales, Sung Ly, and Howard A. Baylis PMCID: PMC2274882 An Essential Role for DYF-11/MIP-T3 in Assembling Functional Intraflagellar Transport Complexes Chunmei Li, Peter N. Inglis, Carmen C. Leitch, Evgeni Efimenko, Norann A. Zaghloul, Calvin A. Mok, Erica E. Davis, Nathan J. Bialas, Michael P. Healey, Elise Héon, Mei Zhen, Peter Swoboda, Nicholas Katsanis, and Michel R. Leroux PMCID: PMC2268012 Global Chromatin Domain Organization of the Drosophila Genome Elzo de Wit, Ulrich Braunschweig, Frauke Greil, Harmen J. Bussemaker, and Bas van Steensel PMCID: PMC2274884 Corrections Correction: The Genetic Structure of Pacific Islanders Jonathan S Friedlaender, Françoise R Friedlaender, Floyd A Reed, Kenneth K Kidd, Judith R Kidd, Geoffrey K Chambers, Rodney A Lea, Jun-Hun Loo, George Koki, Jason A Hodgson, D. Andrew Merriwether, and James L Weber PMCID: PMC2637087 Corrects: Jonathan S Friedlaender, et al. The Genetic Structure of Pacific Islanders. PLoS Genet. 2008 January; 4(1): e19. Correction: Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region Daan Noordermeer, Miguel R. Branco, Erik Splinter, Petra Klous, Wilfred van IJcken, Sigrid Swagemakers, Manousos Koutsourakis, Peter van der Spek, Ana Pombo, and Wouter de Laat PMCID: PMC2637086 Corrects: Daan Noordermeer, et al. Transcription and Chromatin Organization of a Housekeeping Gene Cluster Containing an Integrated β-Globin Locus Control Region. PLoS Genet. 2008 March; 4(3): e1000016. |
