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Research >
Biotechnology and Genomics
The latter part of the 20th century witnessed a
biological revolution that opened new horizons in the life sciences
and created an entirely new industry — biotechnology. California's
world-class research universities placed the state at the forefront
of that revolution. Home to one-third of the nation's biotechnology
firms. California has more biotech jobs than all of the other states
combined.
One in four U.S. biotech companies is located within 35 miles of
a UC campus. One in three California biotech firms (and one in six nationwide) was founded by
UC scientists, and 85% of California biotech firms employ UC alumni
with graduate degrees.
During the next half-century, the application of the quantitative
sciences — mathematics, physics, chemistry and engineering
— to biomedical research brings about a second revolution
that promises to improve human health and create dynamic new technologies.
Visit these UC web sites to learn more about how the University
of California is charting the future course of biotechnology, genomics and bioinformatics.
UC Discovery Grant
UC Discovery
Grants are awarded by the Industry-University Cooperative
Research Program to strengthen and expand California's economy
through UC-industry research partnerships in biotechnology and
other fields. They are state-funded matching grants for expanding
company participation in UC
research and accelerating growth of California R&D firms. Grants
are awarded for research in a broad spectrum of biotechnology areas,
including agriculture, biomaterials, medicine, engineering, genomics,
veterinary science, and environmental and marine sciences. More
than 300 California companies — including many small businesses
— participate in this UC program.
UC
Systemwide Biotechnology Research and Education
Created to ensure a foundation for future scientific advances through
strong new science and the development of highly skilled personnel,
this systemwide
biotech program provides support for biotech research, promotes
graduate and postdoctoral training, and informs government officials,
industry leaders and the public about biotech developments and impacts.
Institute
for Quantitative Biosciences (QB3)
One of four California
Institutes for Science and Innovation, the Institute
for Quantitative Biosciences builds on strengths in
engineering and physical sciences at UC Berkeley, the mathematical
sciences at UC Santa Cruz and the medical sciences at UC San Francisco,
as well as on strong biology programs at these three campuses. Check out the latest UCSF campus at Mission Bay.
Biotech research is also conducted at two other California Institutes
for Science and Innovation:
California Institute for
Telecommunications and Information Technology - Cal-(IT)²
California NanoSystems Institute
Center for Information Technology Research in the Interest of Society
(CITRIS)
Joint
Genomics Institute (National
Laboratories)
The
Joint Genomics Institute is a collaboration of the Berkeley,
Livermore and Los Alamos laboratories funded by the Department of
Energy. Visit Health Research
at the National Labs for more UC biotech research.
Berkeley
Program in Genomics
Genomic information is revolutionizing the way biological and biomedical
problems are defined,m approached and ultimately solved. In Berkeley,
over 30 research groups are actively working to develop new technologies
for the rapid acquisition of biological information on a genomic
scale, exploit these technologies to solve essential biomedical
problems, and create new computational approaches to analyzing the
resulting data.
Berkeley Graduate Program in Computational and Genomic Biology
Berkeley Center for Integrative Genomics
The Center for Integrative Genomics brings together researchers from several traditionally isolated fields of study to analyze and compare the genome sequences of a broad spectrum of organisms to determine the mechanisms responsible for evolutionary diversity among animals, plants and microbes. Faculty are drawn from a number of academic departments at UC Berkeley and the Lawrence Berkeley National Laboratory, including molecular and cellular biology, integrative biology, statistics, computer science, bioengineering, plant and microbial biology, biostatistics, mathematics, physics and public health.
Davis
Genome Center
The Davis
Genome Center will include scientists specializing in gene studies
from a multitude of disciplines, including human and animal medicine,
engineering, agriculture, and the biological and physical sciences
as well as a revitalized pharmacology and toxicology department
in the School of Medicine and a group of bioinformatics faculty
members. Also visit Davis
Biotechnology Program and Designated
Emphasis in Biotechnology.
Irvine
Institute for Genomics and Bioinformatics
The UC Irvine
Institute for Genomics and Bioinformatics will educate the next
generation of computational biologists and work with established
companies, start-ups, government agencies and standards bodies to
develop and transfer genomic and bioinformatic technologies to widespread,
practical applications. Also visit Irvine's
Biomedical Informatics Graduate Training Program.
UCLA
Bioinformatics Institute
Involving faculty members from 10 departments, UCLA
Bioinformatics brings together the avalanche of systematic biological
data — genomes — with the theory and tools of mathematics
and computer science. Also visit UCLA Human Genetics.
Merced Center for Computational Biology
Research projects at the UC Merced Center for Computational Biology focus on mathematical, computational and biological applications, involving methods development or applied simulations where the modeling drives biological insight, rather than being used as a tool for analyzing biological data. These projects also provide rich research opportunities for undergraduate and graduate students in biology and the mathematical and computational sciences.
Merced Genome Center
New funding will enable UC Merced researchers to continue their advanced genomics research at a high-end, cooperative laboratory facility that will include computers, robots and other equipment to help scientists study the genes of all kinds of organisms, from bacteria to sea creatures to human beings. The center will further UC Merced's "Core Labs" approach to research, which encourages professors to collaborate in building efficient, shared centers that house the technology needed to build knowledge in the interdisciplinary fields of the 21st century.
Riverside Institute for Integrative Genome Biology
In an era of rapid genomics-based discovery, the UC
Riverside Institute for Integrative Genome Biology brings a multidisciplinary approach
to foster innovations that will make possible advancements in the
quality of life – from greater agricultural productivity and
more nutritious foods to improved human health and environmental
quality. The institute will support advanced studies in genomics,
gene expression, proteomics, microscopy and bioinformatics, and
also includes the Center
for Plant Cell Biology. Also visit
the University Research Park.
Riverside
Biotechnology Impacts Center
The rapid pace of technical developments in genomics has intensified
public debate on the social impacts of biotechnology. The
Biotechnology Impacts Center will serve as an "honest broker"
forum to identify policy issues, act as an information clearinghouse
and initiate research that addresses the potential benefits and
consequences of the genomics revolution.
San
Diego Biomedical Genomics Microarray Facility
BIOGEM helps meet the needs of multiple labs interested in microarray
technology, which has, together with genome sequencing efforts
resulted in revolutionary
changes in how biomedical research can be done. Differences in
the levels of expression for thousands of genes can be assessed
all
at the same time in a single, simple experiment. Also visit the Whitaker Institute for
Biomedical Engineering, UCSD's
Interdisciplinary Bioinformatics Program and research
projects in bioinformatics and computational biology. The Center
for Marine Biotechnology and Biomedicine at Scripps explores
biotech in the water and new cures under the sea.
San Diego Scripps Genome Center
The Scripps Genome Center will harness the vast potential of studying genomes and genetic coding by combining the latest in computer and information technology with the existing biological and marine science leadership at UCSD's Scripps Institution of Oceanography. The center will address important ocean issues as well as those related to human health, the environment and other areas.
San
Francisco Biological and Medical Informatics
Recognizing that biology and medicine are rapidly becoming data-intensive
sciences that require the generation, management, and analysis of
complex, heterogeneous information, UCSF's
Biological and Medical Informatics Graduate Program conducts
research and training to promote the study, use, and development
of informatics technologies for research and more effective patient
care. Also visit UCSF's
Core Facility for Genomics and Proteomics.
San Francisco Center for BioEntrepreneurship
The UCSF Center for BioEntrepreneurship is
creating the next generation of leaders in life science entrepreneurship
and industry, and
weaving the UC community into the wider fabric of leading companies,
financiers and professionals necessary for the successful migration
of discoveries from the laboratory to commercialization for
the benefit of the institution and society.
Santa
Barbara Data Mining and Bioinformatics Laboratory
The
UCSB Data Mining and Bioinformatics Laboratory provide software tools for
analyzing genomics and proteomics data and applies such tools
in other areas
of computer science.
Santa
Cruz Center for Biomolecular
Science and Engineering
Located close to Silicon Valley and the San Francisco Bay Area
biotech community, Santa Cruz's Center
for Biomolecular Science and Engineering is meeting
the challenges of the post-genomic era resulting from completion
of the Human
Genome
Project. Also visit the UCSC
Computational Biology group. UCSC
is one of the few universities in the country to offer B.S.,
M.S. and Ph.D. in bioinformatics.
California's
Biotechnology Story
San
Francisco Biotechnology Archives - UC contributions to
the growth and development of the
biotechnology industry
UC Technology Transfer Annual Reports
Health Research at UC-Managed
National Laboratories
San Diego Supercomputing
Center - Integrative Bioscience
UC Health Professional Schools
UC Health News
UC stem cell research fact sheet
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Two new buildings at the Santa Cruz campus —
the Physical
Sciences Building (top) and the Engineering
II Building — will provide more than 10,000 square feet
of research and office space for the multicampus Institute
for Quantitative Biosciences.
UC and Biotechnology
To ensure that UC will continue to play a crucial role in the research
discoveries that fuel the multi-billion dollar bio-technology industry,
the UC
Discovery Grant program builds links between UC researchers
and California business with the goal of fostering research, positioning
California for international competitiveness in emerging areas
of biotechnology and identifying biotech solutions to important
statewide problems.
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