Research Centers
Environmental Lung Disease Center (National Jewish Medical and Research Center)
National Jewish Medical and Research Center
The objectives of the Environmental Lung Disease Center are to improve the understanding of lung disease, and develop innovative early disease detection, prevention and treatment approaches. The center's research involves: 1) determining the molecular mechanisms of environmental and occupational lung disease, 2) identifying the genetic and molecular basis for individual susceptibility, and 3) identifying the risk and effects of air pollution on human population with preexisting pulmonary diseases, and the exposure/host response relationship that leads to disease. Besides immunologic diseases, the project will focus on respiratory, allergic, and infectious diseases, through an integrated program of basic and clinical research.
Center Publications:
Views: | All publications | Selected publication types | Journal articles | Publications submitted after final report |
View Projects in Tabular Format
Main Center Abstract and Reports:
Asthma Indices Associated with Ambient Submicron Particles and Formaldehyde in Ambient Air Pollution
Immunologic Basis of Environmental Lung Disease
Center Research Projects:
R825702C001 - SP-A and SP-D in Environmental Lung Disease
R825702C003 - Adaptation to Nitrogen Dioxide: Role of Altered Glycolytic Pathway Enzyme Expression and NF-κB-Dependent Cellular Defenses Against Apoptosis
R825702C005 - Inhalation of Particulate Matter Alters the Allergic Airway Response to Inhaled Allergen
R825702C006 - Particle-Induced Lung Inflammation and Extracellular EC-SOD
R825702C007 - Indoor-Outdoor Relationships of Airborne Particle Count and Endotoxin Concentrations
R825702C008 - The Role of Mitochondrial DNA Mutations in Oxidant-Mediated Lung Injury
R825702C009 - Immunopathogenesis of Hypersensitivity Pneumonitis in the Mouse
R825702C010 - Activation of Natural T Lymphocytes by Diesel Exhaust Particulates Leads to Their Production of Interleukin-4 and TH2 Lymphocyte Differentiation to Allergen
R825702C011 - Latex Antigen Levels During Powdered and Powderless Glove Use
R825702C012 - Adjuvant Effects of Ozone in a Model of Allergen-Induced Airway Inflammation and Hyperresponsiveness
R825702C013 - Acute Exposure to Particulate Air Pollution in Childhood Asthma
R825702C014 - Mechanisms of Ozone Toxicity to the Lung