Integrated Risk Information System (IRIS)

IRIS (Integrated Risk Information System) is a compilation of electronic reports on specific substances found in the environment and their potential to cause human health effects. IRIS was initially developed for EPA staff in response to a growing demand for consistent information on substances for use in risk assessments, decision-making and regulatory activities. The information in IRIS is intended for those without extensive training in toxicology, but with some knowledge of health sciences.

Getting Started with IRIS

An overview of the web site What is IRIS? How does EPA decide which substances to add or update? More frequent questions >>

Using the IRIS Database

IRIS Process (2008 Update) Advanced Search in IRIS Compare IRIS Values Download IRIS

New Assessments and Reviews

The following documents are new assessments or under external peer review at this time: More Recent Additions >> Substance Milestone Uploaded Date Propionaldehyde Final Assessment 9/30/2008 Decabromodiphenyl ether (BDE-209) Final Assessment 6/30/2008 Hexabromodiphenyl ether (BDE-153) Final Assessment 6/30/2008 Pentabromodiphenyl ether (BDE-99) Final Assessment 6/30/2008 Tetrabromodiphenyl ether (BDE-47) Final Assessment 6/30/2008 Tetrachloroethylene (Perchloroethylene) External Peer Review 6/26/2008