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Acceptable Substitutes in Household and Light Commercial Air Conditioning

Ozone Protection Hotline (800) 296-1996

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is available from the hotline. If your browser is unable to display tables, please call the hotline for a free paper copy.

Unacceptable substitutes

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Acceptable Substitutes for CFCs (class I ODS) in Household & Light Commercial AC

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
Evaporative/Desiccant Cooling   all CFCs N
R-407C Suva 407C, Klea 407C 502 R, N
R-422C ICOR XLT1 502 R, N
Key: R = Retrofit Uses, N = New Uses

Acceptable Substitutes for HCFCs (class II ODS) in Household & Light Commercial AC

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
HFC-134a   22 N
THR-03   22 N
NOTE: this determination applies ONLY to window-unit residential air conditioning, and not to central air conditioning systems.
ISCEON 59, NU-22, R-417A Isceon 59, NU-22 22 R, N
R-410A, R-410B AZ-20, Suva 9100, Puron 22 N
R-407C Suva 9000, Klea 66 22 R, N
R-507, R-507A AZ-50 22 R, N
NU-22 NU-22 22 R, N
Ammonia Absorption   22 N
Evaporative/Desiccant Cooling   all HCFCs N
R-404A HP62 22 R, N
R-125/134a/600a (28.1/70.0/1.9)   22 R, N
RS-44 RS-44 22 R, N
R-421A Choice R421A 22 R, N
R-422D ISCEON MO29 22 R, N
R-424A RS-44 22 R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22 R, N
R-422C ICOR XLT1 22 R, N
R-422B ICOR XAC1 22 R, N
KDD5 KDD5 22 R, N
RS-45 (ASHRAE proposed designation: R-434A) RS-45 22 R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22 R, N
R-422B XAC1, NU-22B 22 R, N
R-422C XLT1 22, 402A, 402B, 408A R, N
Key: R = Retrofit Uses, N = New Uses

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