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Science Products
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Science Products
This page provides information on selected scientific papers, reports, and other references produced by researchers in the Human Health Research Program.
Research papers are available from published journals or through PubMed, a service of the U.S. National Library of Medicine that includes over 16 million citations from MEDLINE and other life science journals for biomedical articles.
A list of the Human Health Research Program's most highly cited publications (PDF) (27 pp, 274K) demonstrates the program's impact on advancing human health research.
To obtain copies of ORD (and other EPA) documents:
- National Service Center for Environmental Publications (NSCEP): NSCEP is EPA's central repository of all EPA documents with over 7,000 titles available in paper or electronic form.NSCEP also produces the EPA National Publications Catalog which is available on their web site.
- National Environmental Publications Internet Site (NEPIS): NSPIS is EPA's largest electronic documents site which allows you to search view and print, including full images of all original pages and full-text, from a collection of over 10,000 archival and current documents. This collection may include documents that are no longer available in print form. ORD publications are listed at "Publication Title List - 600 Series."
Exposures Factor Handbook
The Exposure Factors Handbook provides a summary of the available statistical data on various factors used in assessing human exposure. This handbook provides data on standard factors to calculate human exposure to toxic chemicals. These factors include: drinking water consumption, soil ingestion, inhalation rates, dermal factors including skin area and soil adherence factors, consumption of fruits and vegetables, fish, meats, dairy products, homegrown foods, breast milk intake, human activity factors, consumer product use, and residential characteristics.
Contact: Technical Information Staff, telephone, 202-564-3261, email: nceadc.comment@epa.gov
Child-Specific Exposure Factors Handbook
The Child-specific Exposure Factors Handbook 2006 provides a summary of the available and up-to-date statistical data on various factors assessing child exposures. These factors include drinking water consumption, soil ingestion, inhalation rates, dermal factors including skin area and soil adherence factors, consumption of fruits and vegetables, fish, meats, dairy products, homegrown foods, breast milk, activity patterns, body weight, consumer products and life expectancy.
Contact: Technical Information Staff, telephone, 202-564-3261, email: nceadc.comment@epa.gov
Benchmark Dose Software
Benchmark Dose Software (BMDS) is a tool developed to facilitate the application of benchmark dose (BMD) methods to EPA hazardous pollutant risk assessments. EPA uses BMD methods to estimate reference doses (RfDs) and reference concentrations (RfCs), which are used along with other scientific information to set standards for noncancer human health effects.
Contact: Technical Information Staff, telephone, 202-564-3261, email: nceadc.comment@epa.gov
Guidelines for Carcinogen Risk Assessment
The revised Guidelines for Carcinogen Risk Assessment 2005 provide a framework for assessing possible cancer risks from exposures to pollutants or other agents in the environment. Revisions to the Cancer Guidelines are intended to make greater use of the increasing scientific understanding of processes of cancer development.
Contact: Technical Information Staff, telephone, 202-564-3261, email: nceadc.comment@epa.gov
Report on Reference Dose and Reference Concentration Processes
The report, "A Review of the Reference Dose and Reference Concentration Processes," summarizes the review and deliberations of the Risk Assessment Forum's Reference Dose and Reference Concentration Technical Panel and its recommendations for improvements in the process of deriving reference values, including setting less than lifetime as well as chronic reference values. The document is a review, not guidance, and it evaluates the current state-of-the-art for hazard characterization with a focus on protection of potentially sensitive subpopulations.
Organophosphate Cumulative Risk Assessment
The organophosphate Cumulative Risk Assessment provides information about cumulative risk assessments of organophosphates and carbamate pesticides. EPA developed the risk assessment as part of an ongoing process for making pesticide reregistration eligibility and tolerance reassessment decisions.
Chromated Copper Arsenate (CCA) technical guidance
The Agency has worked with pesticide manufacturers to voluntarily phase out chromated copper arsenate (CCA) use for wood products around the home and in children's play areas. Effective December 31, 2003, no wood treater or manufacturer may treat wood with CCA for residential uses, with certain exceptions. Technical guidance on assessing exposure is available at: Probabilistic Exposure Model for Risk Assessment of Chromated Copper Arsenate (CCA).
Exposure Databases
Technology Transfer Network
Air Pollutants Exposure Model
Consolidated Human Activity Database (CHAD)
Human Exposure Database System (HEDS)
Children's Total Exposure to Persistent Pesticides Study
Framework for Assessing Risks of Environmental Exposures to Children