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HuGENet e-Journal
e-Journal Club
Summary Template 

Note: If you complete this form on line, you cannot save the data so please enter all information before submitting. Alternatively, e-Journal reviewers may either print and work from this page or download a Download Word Document Link here to download Word Reader (44KB).

>> See sample of a completed e-journal summary.

Provide title for review

Reviewed by 
List name(s) of individual(s) who reviewed article for e-journal club 
 
Affiliated agency
For each individual listed above, indicate affiliation
 
The Health Outcome 
Describe disease or health outcome, including information on public health significance (prevalence, morbidity, mortality). Include information on genetic association with the health outcome.
 
The Finding 
Report the findings of the study. Include type of study, study participant information, a description of the genetic component to the study, major results, and the author's conclusion. 
 
Public Health Implications 
Define how the information may or may not impact public health, prevention and or treatment of the disease. Identify gaps in knowledge, where additional research is needed.
 
References
List references numerically corresponding to reference in text, in the format listed below:
[First Author Last Name] [First Name Initial] , et al. Title of Journal Article. Journal Title. 2001 Month; volume (issue): pages.



Abstraction Template

Note: If you complete this form on line, you cannot save the data so please enter all information before submitting. Alternatively, e-Journal reviewers may either print and work from this page or download a Download Word Document Link here to download Word Reader (75KB).

>> See sample of a completed e-journal abstract
 

 Key Variables and  Description  Article
Reference
Complete the bibliographic reference for the article according to AJE format.

 

Category of HuGE information
Listing of the type of information in the article:
  1. Prevalence of gene variant 
  2. Gene-disease association
  3. Gene-environment interaction
  4. Gene-gene interaction
  5. Genetic test evaluation/ monitoring
Study hypotheses or purpose
State the authors study hypotheses or main purpose for conducting the study.

 

Gene(s)
Identify the following:
  • Gene name
  • Chromosome location
  • Gene product/function
  • Alleles
  • OMIM #
Environmental factor(s) OR Intervention
Identify the major environmental factors studied (infectious, chemical, physical, nutritional, and behavioral)

 

Health outcome(s)
Identify the major health outcome(s) studied.

 

Study design
Specify the types of study designs (from the list below) in the article:
  1. Case-control
  2. Cohort
  3. Cross-sectional
  4. Descriptive or case-series
  5. Clinical trial
  6. Population screening

 

Case definition
For study designs 1, 4 and 5, define the following if available:
  • Disease case definition
  • Exclusion criteria
  • Gender
  • Race/ethnicity
  • Age
  • Time period
  • Geographic location
  • Number of participants (% of total eligible)

 
Control definition
For study designs 1, define the following if available:
  • Control selection criteria
  • Matching variables
  • Exclusion criteria
  • Gender
  • Race/ethnicity
  • Age
  • Time period
  • Geographic location
  • Number of participants (% of total eligible)

 

Cohort definition
For study designs 2, 3, and 6, define the following if available:
  • Cohort selection criteria
  • Exclusion criteria
  • Gender
  • Race/ethnicity
  • Age
  • Time period
  • Geographic location
  • Number of participants (% of total eligible)

 

Assessment of environment factors
For studies that include gene-environment interactions, define
the following if available:
  • Environmental factor
  • Exposure assessment
  • Exposure definition
  • Number of participants
    with exposure data (% of total eligible)

 

Genotyping
Specify the following:
  • Gene
  • DNA source
  • Methodology
  • Number of participants genotyped (% of total eligible)

 

Analysis
Comment on the analysis carried out by the author(s). E.g. matching, modeling or statistical test used. Were the analyses appropriate?

 

 

Results
Specification of the major results under each of the following HuGE categories, including tables when data is provided.

  1. Prevalence of gene variant
  2. Gene-disease association
  3. Gene-environment interaction
  4. Gene-gene interaction
  5. Genetic test evaluation/
    monitoring



Conclusion
State the author's overall conclusions from the study.

 

 
Comments
Provide additional insight, including methodologic issues and/ or concerns, about the study.

   

Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics