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Thursday, October 4, 2007 |
Volume
19 Number 14 |
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This weekly update provides information about the impact of human genetic research on disease prevention & public health. |
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New article, Family History and Prevalence of Diabetes in the U.S. Population: The 6-year results from the National Health and Nutrition Examination Survey (1999–2004), published in the October 2007 issue of Diabetes Care. Authors: Valdez R, Yoon PW, Liu T and Khoury MJ |
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New HuGE publication, Assessment of Cumulative Evidence on Genetic Associations: Interim Guidelines, published in the September 2007 issue of the International Journal of Epidemiology. Authors: Ioannidis JPA, Boffetta P, Little J, O’Brien TR, Uitterlinden AG, Vineis P, et al. |
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View remarks by HHS Secretary Michael O. Leavitt and presentations given at the 21st Century Medicine: Personalized and Evidence-Based event hosted by the Personalized Medicine Coalition and Georgetown University School of Nursing & Health Studies on September 18-19, 2007. |
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Join the Mid-West Community Genetics Forum on Genomics, Community and Equity: A Continuing Dialogue presented by the University of Michigan, Center for Public Health and Community Genomics on October 12, 2007. Forums will be held in Illinois, Iowa, Michigan, Minnesota, and Missouri. |
- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Cancer |
Gastric cancer trial seeks 'genetic fingerprint' for predicting drug effectiveness, Medical News Today, October 4 |
Genomic profiling of lung tumors helps doctors choose most effective treatment, News-Medical.Net, September 30 |
Scientists identify six types of breast cancer, The Independent, October 3 |
Researchers at IRB Barcelona discover one of the mechanisms that prevents the spread of colon cancer, EurekAlert, September 30 |
Notch gene may lead to new methods of beating breast cancer, News-Medical.Net, October 2 |
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Mental Health |
Epilepsy in infants caused by genetic
mutation, Medical News Today, October 4 |
Genes tied to bad reactions to antidepressant
drug, New York Times, September 28 |
Genes linked to suicide risk in some patients, NPR, September 28 |
Genetic test announced for suicidal ideation in patients using antidepressant drugs, EurekAlert, September 27 |
Schizophrenia candidate genes affect even healthy individuals, News-Medical.Net, September 28 |
Genes linked to suicidal thinking during antidepressant treatment, NIH News, September 27 |
Other News |
PAZAR offers free shopping in a virtual bazaar of gene regulation data, Medical News Today, October 4 |
Mission impossible: A routine childhood, The New York Times, September 30 |
First significant genetic finding in severe premenstrual dysphoric disorder, News-Medical.Net, October 2 |
Toxic buildup in brain from loss of gene responsible for some dementias, Medical News Today, September 30 |
Genetics and learning, News-Medical.Net, October 2 |
'Jumping genes' could make for safer gene delivery system, Medical News Today, September 28 |
24 million Thais carry genetic trait for
thalassemia, News-Medical.Net, October 2 |
454 sequencing uncovers significant genetic variation, EurekAlert, September 27 |
Gene mutation tied to early-onset Parkinson disease,
(last accessed 2/2008) Reuters Health, October 1 |
Gene-hunting facility funded by federal 'genes and environment' grant, Medical News Today, September 27 |
Gene that lowers cell stress could protect against Parkinson's disease, News-Medical.Net, October 1 |
Genetics Clinic Set for Oct. 13, The Ellsworth American, September 27 |
microRNAs may be key to HIV's ability to hide, evade drugs, News-Medical.Net, October 1 |
Individual differences caused by shuffled chunks of DNA in the human genome, EurekAlert, September 27 |
NIH launches extensive open-access dataset of genetic and clinical data, NIH News, October 1 |
Successful strategies for probing genetic variation presented in new book, Medical News Today, September 27 |
Smoking is a turn-on for some genes: study,
(last accessed 2/2008) Reuters Health, October 1 |
New group to study genetic link to drug risks, Reuters Health, September 27 |
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Effects of environment, genetics and data analysis pitfalls in an esophageal cancer genome-wide association study
Statnikov A, et al.
PLoS ONE 2007;2(9):e958
Genomics and the future of pharmacotherapy in psychiatry
Malhotra AK, et al.
Int Rev Psychiatry 2007 Oct;19(5):523-30
Contribution of hierarchical clustering techniques to the modeling of the geographic distribution of genetic polymorphisms associated with chronic inflammatory diseases in the Quebec population
Madore AM, et al.
Community Genet 2007;10(4):218-26
Genetic association studies; the good, the bad, and the ugly
Donahue MP & Kraus WE
Am Heart J 2007 Oct;154(4):610-2
Population attributable fraction: its implications for genetic epidemiology and illness prevention
Karp I, et al.
Am Heart J 2007 Oct;154(4):607-9
Beyond "misunderstanding": Written information and decisions about taking part in a genetic epidemiology study
Dixon-Woods M, et al.
Soc Sci Med 2007 Sep
Genetic epidemiology of primary sclerosing cholangitis
Karlsen TH, et al.
World J Gastroenterol 2007 Nov;13(41):5421-31
Genetic variation of estrogen metabolism and the risks of cardiovascular disease
Almeida S & Hutz MH
Curr Opin Investig Drugs 2007 Oct;8(10):814-20
Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues
Gage BF & Lesko LJ
J Thromb Thrombolysis 2007 Oct
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports
Cupples LA, et al.
BMC Med Genet 2007 Sep;8 Suppl 1:S1
Danger zones: risk perceptions of young women from families with hereditary breast and ovarian cancer
Werner-Lin AV
Fam Process 2007 Sep;46(3):335-49
Increased cancer risk for individuals with a family history of prostate cancer, colorectal cancer, and melanoma and their associated screening recommendations and practices
Noe M, et al.
Cancer Causes Control 2007 Sep
Genetics of migraine headache in children
Hershey AD
Curr Pain Headache Rep 2007 Oct;11(5):390-5
The presence of family history and the development of type 2 diabetes mellitus risk factors in rural children
Adams MH & Lammon CA
J Sch Nurs 2007 Oct;23(5):259-66
Modification of risk for subsequent cancer after female breast cancer by a family history of breast cancer
Hemminki K, et al.
Breast Cancer Res Treat 2007 Sep
Sociodemographic, Family History, and Lifestyle Risk Factors for Open-angle Glaucoma and Ocular Hypertension The Los Angeles Latino Eye Study
Doshi V, et al.
Ophthalmology 2007 Sep
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page
For the week ending October 3, 2007, there are HuGE articles in the following areas:
Gene Variant Frequency
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions
For more information on HuGE, please visit the HuGENet™ home page |
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Provides link to non-governmental sites and does not necessarily represent the views of the Centers for Disease Control and Prevention. |
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