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 Thursday, March 2, 2006     Volume 16   Number 9  
Genomics & Health Weekly Update Genomics & Health Weekly Update Family History Genomics & Health Weekly Update Family History Population Research Genomics in Practice General Public
 This weekly update provides information about the impact of human genetic research on disease prevention  and public health.
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Genomics and Public Health - June 4-7, 2006
International Conference on “Genomics and Public Health”
This conference will address key questions relating to genomics and public health, including newborn screening programs, the role of international stakeholders, the role of citizens, and more.  Co-organizers include the University of Montreal,
Centers for Disease Control and Prevention, Public Health Genetics Unit, and the Public Health Agency of Canada. 
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CDC Announcements
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Family history of type 2 diabetes: A population-based screening tool for prevention
Hariri et al.
Genet Med 2006 Feb;8(2):102-108

   
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Inaugural Meeting - CDC Public Health Genomics Collaboration
March 17, 2006 ~ Atlanta, Georgia
Meeting open to CDC employees/contractors only

   
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From public health emergency to public health services: the implications for evolving criteria for newborn screening panels This reference links to a non-governmental website
Grosse S. et al. Pediatrics March 2006
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Genomics In The News
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  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press and do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
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“Genetic Link Found Between Eating Disorders And Obsessive Compulsive Disorder” This reference links to a non-governmental website
(February 25) Medical News Today reports, “Researchers at the University of Toronto have unravelled the genetic link between eating disorders and obsessive compulsive disorder (OCD) among women who experience both syndromes.”

“OECD countries agree Guidelines on licensing of healthcare genetics” This reference links to a non-governmental website (last accessed 2/2008)
(March 1) OECD reports, “OECD member countries have adopted an agreed set of Guidelines for the Licensing of Genetic Inventions used in healthcare, in a move designed to help people benefit more widely from advances in genetics while making research and innovation faster and more efficient.”

“Gene linked to depression risk” This reference links to a non-governmental website
(March 1) ABC News Online reports, “Australian researchers say more than a fifth of the population has a genetic predisposition to major depression triggered by a string of stressful life events.”

“Call for new genetic testing technologies” This reference links to a non-governmental website
(March 1) Laboratorytalk reports, “EuroGentest, the European Network of Excellence aiming at harmonising genetic testing services throughout Europe, has announced an urgent 'Call for new Innovative Techniques in Genome Diagnostics'.”

“Cell-death mechanism linked to developmental and degenerative brain disorders” This reference links to a non-governmental website
(March 1) News Medical.net reports, “An international research team has provided the first conclusive evidence that neurodevelopmental disorders such as mental retardation and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and ataxias can be caused, at least in part, by specific gene defects that interfere with the electrical impulses of rapid-firing brain nerve cells called bursting neurons.”

“Genes For Virulence In Strain Of Community-acquired MRSA Uncovered By Scientists” This reference links to a non-governmental website
(February 28) Medical News Today reports, “Scientists have identified the genes responsible for the resistance and virulence of one of the most predominant strains of community-acquired meticillin-resistant Staphylococcus aureus (MRSA) in the US.”

“Study: Gene Therapy Doesn't Cause Tumors” This reference links to a non-governmental website
(February 28) The Post Chronicle reports, “Yale University scientists say they've determined gene therapy used to create new arteries for older patients doesn't appear to cause cancer.”

“Gene Therapy Cancer Boost” This reference links to a non-governmental website
(February 28) Sky News Today reports, “Scientists have developed a method which could protect the healthy cells of cancer patients undergoing radiotherapy.”

“Scientists Find Variants Of Blood Clotting Genes Increase Risk Of Coronary Disease” This reference links to a non-governmental website
(February 27) Medical News Today reports, “Rare variants of two genes that regulate blood clotting may each increase a person's risk of coronary disease by about 15%, according to a meta-analysis in this week's issue of The Lancet.”

“Scientists arrive at novel method to identify genes” This reference links to a non-governmental website (last accessed 2/2008)
(February 27) Khaleej Times reports, “In a major advance, scientists in Bangalore — working with an American team — have found a novel way to identify new genes involved in genetic diseases.”

“Taste genes may yield important information about who smokes and why they smoke” This reference links to a non-governmental website
(February 27) News Medical.net reports, “Recent research on the genetics of smoking has focused on genes that are thought to be related to nicotine metabolism, personality traits, and regulation of emotions.”

“Alcoholism, Smoking And Genetics Among Plains American Indians” This reference links to a non-governmental website
(February 26) Medical News Today reports, “Alcoholism and smoking have a high rate of co-occurrence in the general population.”

“Gene Test Could Spot Athletes' Cardiac Risk”
(February 24) Medline Plus reports, “A rare, often fatal heart condition in young athletes could have its roots in a group of mutations in one gene, new research suggests.”

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Genomics in Scientific Literature
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Family history of type 2 diabetes: A population-based screening tool for prevention?
Hariri S, et al.
Genet Med 2006 Feb;8(2):102-8

Estimation and testing of genotype and haplotype effects in case-control studies: comparison of weighted regression and multiple imputation procedures
Cordell HJ
Genet Epidemiol 2006 Feb

Improved association analyses of disease subtypes in case-parent triads
Epstein MP, et al.
Genet Epidemiol 2006 Feb

Surveillance of women at high risk for hereditary ovarian cancer is inefficient
Oei AL, et al.
Br J Cancer 2006 Feb

Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
Edvardsen H, et al.
Pharmacogenet Genomics 2006 Mar;16(3):207-17

Breast and Ovarian Cancer in Relatives of Cancer Patients, with and without BRCA Mutations
Lee JS, et al.
Cancer Epidemiol Biomarkers Prev 2006 Feb;15(2):359-63

The role of genetic polymorphisms in alcoholic liver disease
Stickel F & Osterreicher CH
Alcohol Alcohol 2006 Feb

Gene-environment interplay and psychopathology: multiple varieties but real effects
Rutter M, et al.
J Child Psychol Psychiatry 2006 Mar;47(3-4):226-61

Getting ready for the future: integration of genomics into public health research, policy and practice in europe and globally
Brand A, et al.
Community Genet 2006;9(1):67-71

Genetic counseling for the public?
Kunstmann E & Epplen JT
Community Genet 2006;9(1):62-6

PopGen: Population-Based Recruitment of Patients and Controls for the Analysis of Complex Genotype-Phenotype Relationships
Krawczak M, et al.
Community Genet 2006;9(1):55-61

The spectre of coercion: is public health genetics the route to policies of enforced disease prevention?
van den Daele W
Community Genet 2006;9(1):40-9

Genomics and public health in the United States: signposts on the translation highway
Gwinn M & Khoury MJ
Community Genet 2006;9(1):21-6

What role for public health in genetics and vice versa?
Holtzman NA
Community Genet 2006;9(1):8-20

So many studies, too few subjects: establishing functional relevance of genetic polymorphisms on pharmacokinetics
Williams JA, et al.
J Clin Pharmacol 2006 Mar;46(3):258-64

Genetics, pathology, and clinics of familial gastric cancer
Oliveira C, et al.
Int J Surg Pathol 2006 Jan;14(1):21-33

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HuGE Published Literature
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending March 1, 2006, there are HuGE articles in the following areas:

Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 
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Upcoming Events
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New this week

Association of Professors of Human and Medical Genetics 12th Annual Workshop This reference links to a non-governmental website
April 26-29, 2006 ~ Marco Island, Florida

2006 Annual Clinical Genetics Meeting This reference links to a non-governmental website (last accessed 2/2008)
March 23-26, 2006 ~ San Diego, California

   
New this week The Genome Access Course This reference links to a non-governmental website (last accessed 2/2008)
April 25-26, 2006 ~ Cold Spring Harbor
August 29-30, 2006 ~ Cold Spring Harbor
November 29-30, 2006 ~ Cold Spring Harbor
   
  Third International Conference GENOMICS & SOCIETY This reference links to a non-governmental website
April 20-21, 2006 ~ Amsterdam, Netherlands
   
New this week 9th Annual Meeting of the American Society of Gene Therapy
May 31 - June 4, 2006 ~ Baltimore, MD
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Let's Go Surfing
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Public Health Genomics European Network (PHGEN) This reference links to a non-governmental website
PHGEN seeks to identify issues and priorities for Public Health Genomics; assess challenges linked to current national practices in applying genetic testing; and identify examples of best practices in applying genetic testing in Europe.

NIH Funding Announcement: Public Consultation to Inform the Design of Possible Large-Scale Studies of Genes and Environment in Common Disease
“The purpose of this funding opportunity is to provide support for a specialized center to conduct a pilot public consultation study to obtain wide societal input to inform the design of a possible large U.S.-based longitudinal cohort study of the role of genes and environment in health and disease.”

Understanding Genetics This reference links to a non-governmental website
An online exhibit created by The Tech Museum of Innovation where one can zoom into DNA, use an interactive eye color calculator, keep up with the latest genetics news and asked a geneticist at Stanford University questions about DNA.

 

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The CDC Office of Genomics and Disease Prevention makes available the above information as a public service only. Providing
this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers for  Disease Control and Prevention.
Page last reviewed: March 2, 2006 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics