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natural human interferon alpha OPC-18 A proprietary preparation of natural human interferon alpha (IFN alpha) with potential immunomodulatory and antineoplastic activities. Natural human interferon alpha OPC-18 binds to cell-surface IFN alpha receptors (IFNARs), resulting in the transcription and translation of genes whose products mediate antiviral, antiproliferative, and immune-modulating effects.
IFN alpha is a type I interferon produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products and is the primary interferon produced by virus-induced leukocyte cultures. In addition to its pronounced antiviral activity, it activates NK cells.
Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) | natural interferon alfa | | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) | Alfaferone | | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) | Code name: | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) | OPC-18 | | ![](https://webarchive.library.unt.edu/eot2008/20081025095843im_/http://www.cancer.gov/images/spacer.gif) |
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