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Sponsors and Collaborators: |
The University of Texas Health Science Center at San Antonio Department of Veterans Affairs |
Information provided by: | The University of Texas Health Science Center at San Antonio |
ClinicalTrials.gov Identifier: | NCT00223483 |
This research study goal is to analyze the plasma and the cells that make up part of the immune system. We want to learn how the plasma and cells work. These may influence why one person will develop an infection and another will not, or why one person develops severe symptoms of a disease while others remain without symptoms.
Condition | Intervention |
Hematologic Diseases Healthy Volunteers |
Genetic: Isolation of genomic DNA |
Study Type: | Observational |
Study Design: | Other, Prospective |
Official Title: | Identification and Analysis of Immunomodulatory Molecules From Leukocytes in Patients With Hematologic Disorders and Healthy Volunteers |
Whole blood, serum, white cells
Estimated Enrollment: | 1000 |
Study Start Date: | March 2005 |
Estimated Study Completion Date: | March 2015 |
This research study goal is to analyze the plasma and the cells that make up part of the immune system. These cells, called white cells or leukocytes, are present in blood. We want to learn how these cells work to prevent infection and how they respond after an infection occurs. We also want to study certain molecules present on the plasma, on or in these cells, and the genetic material that allows these molecules to be made. These molecules may influence why one person will develop an infection and another will not, or why one person develops severe symptoms of a disease while others remain without symptoms. This study may increase our understanding of a variety of diseases including infections such as HIV, allergic diseases such as asthma, joint diseases such as rheumatoid arthritis, certain cancers, and the rejection process that sometimes occurs after transplantation of an organ.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Primary care clinic and community samples
Inclusion Criteria:
Exclusion Criteria:
Contact: Juan J Toro, MD | 210-617-5300 ext 16777 | juantoro2@va.gov |
United States, Texas | |||||
The University of Texas Health Science Center at San Antonio | Recruiting | ||||
San Antonio, Texas, United States, 78229 | |||||
Contact: Juan J Toro, MD 210-617-5300 ext 16777 juantoro2@va.gov | |||||
Principal Investigator: Juan J Toro, MD | |||||
Department of Veterans Affairs, South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division | Recruiting | ||||
San Antonio, Texas, United States, 78229 | |||||
Contact: Juan J Toro, MD 210-617-5300 ext 16777 juantoro2@va.gov | |||||
Principal Investigator: Juan J Toro, MD | |||||
Cancer Therapy & Research Center | Recruiting | ||||
San Antonio, Texas, United States, 78229 | |||||
Contact: Juan J Toro, MD 210-617-5300 ext 16777 juantoro2@va.gov | |||||
Principal Investigator: Juan J Toro, MD |
The University of Texas Health Science Center at San Antonio |
Department of Veterans Affairs |
Study Director: | Cesar O Freytes, MD | The University of Texas Health Science Center at San Antonio |
Responsible Party: | South Texas Veterans Health Care System ( Juan J. Toro ) |
Study ID Numbers: | HSC20040268H |
First Received: | September 13, 2005 |
Last Updated: | December 15, 2007 |
ClinicalTrials.gov Identifier: | NCT00223483 |
Health Authority: | United States: Food and Drug Administration |
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