Available in PDF
In this issue...
DOE '99 Oakland Highlights
Meeting Intro
HGP Progress, Challenges
Joint Genome Institute
JGI Facility Opening
Sequencing
Device Speeds Sequencing
Chromosome 19 Genes
Functional Genomics
Sample Prep System
Informatics
Education & Bioethics
Microbial Genomes
Next Meeting Feb. 2000
Genome Project
Accelerated Timetable
FY1999 Budgets
JGI Refits Facility
Progress
In the News
Drosophila Near Completion
Directors, Researchers Receive Awards
Chromosomes 21, 22 Near Finish
Human MHC Region Sequenced
Mouse Probes Aid Mapping
Genetic Testing Committee
DOE Labs & Biomedicine
Biomedical Engineering Proposals
Drug Firms Create SNP Resource
SBIR 1999 Awards
HUGO News
1999 Hollaender Winners
Microbial Genomics
EcoCyc Database for E. coli
Developing EcoCyc
Thermotoga Sequence
Clostridium Sequenced
Microbial Gene Finder
Neisseria Sequence
Microbial Web Sites
Ethical, Legal, and Social Issues
Education, Counseling Foundation
ELSI Studies
ELSI Retrospective
Protecting Privacy
Informatics
MGI 2.2 Released
DNA Repository
Web, Other Resources, Publications
Metabolic Pathways
New Staden Package
PDB Newsletter
Polymorphism Database
Bacterial Protein Database
DOE BER Publications
HGP Information Web
Biotechnology Business Webs
Behavioral Genetics
Office of Science Reports
Articles on Genetics
Funding
Genome Research Funding
Meeting Calendars & Acronyms
Genome & Biotech Meetings
Training Courses & Workshops
Acronyms
HGN archives & subscriptions
HGP Information home
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In the News
Human MHC Region Sequenced
Key to Transplant Rejection, Autoimmune Disease
Sequencing of the 4-Mb human Major Histocompatibility Complex (MHC) region of chromosome6 has been completed by the Sanger Centre, University of Washington, and Tokai University (www.sanger.ac.uk/HGP/Chr6/MHC.shtml).
Proteins encoded by genes residing in the MHC region are responsible for helping the body defend itself against microscopic invaders by distinguishing normal body constituents ("self") from everything else, which it then marks for extinction. Researchers hope that a better understanding of MHC proteins will lead to the development of new ways to minimize transplant rejection and fight such infectious and autoimmune diseases as arthritis and juvenile diabetes.
The electronic form of the newsletter may be cited in the following
style:
Human Genome Program, U.S. Department of Energy, Human Genome News
(v10n3-4).
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