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Guidelines on Overweight and Obesity: Electronic Textbook |
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3.d. Fitness
Rationale: Two RCTs that examined the effects of weight loss on glucose tolerance in older men (369) and in persons with diabetes (404) also had measures of VO2 max (oxygen consumption) as a measure of fitness. In both studies, physical activity resulted in a net weight loss of approximately 2.3 to 2.5 kg (2 to 3 percent) and increased VO2 max by 9 to 18 percent. In one study (419) most measures of glucose tolerance improved, whereas in the other study (369)only 2 hour insulin improved. Neither study was designed to test whether increased fitness improves glucose tolerance independent of weight loss.
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