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Human Genome News Archive Edition

  Vol.10, No.1-2   February 1999
Available in PDF 
 
In this issue... 

Genome Project 
U.S. HGP on Fast Track 
DOE Joint Genome Institute Exceeds Goal 
New 5-Year Goals 
Faster Sequencing with BACs 
Mapping with STCs and STSs 
Availability of BAC Clones and STC Data 
BAC Related Websites 
BAC Resource Success Story 
Scientists Hunt SNPs for Variation, Disease 
Who's Sequencing the Human Genome? 
Genomics Progress in Science 
EMSL Promotes Remote Access to Instrumentation 
Second Private-Sector Sequencing Project 
GeneMap'98 

In the News 
Team Delivers C. elegans Sequence 
Why Sequence Entire Genomes? Worm's Eye View 
Embnet.news on Web 
European Biotech Program 
DOE BER Research Update 
Hollaender Fellows Named 
SBIR 1998 Human Genome Awards Announced 
Mouse Resources 
Mouse Consortium for Functional Genomics 
Chlamydia Genome Analysis 
HUGO Merges Offices, Web Sites 

Microbial Genomics 
Superbug Deinococcus radiodurans 
Unfinished Microbial Genomes Searchable 
TIGR Releases Chlorobium tepidum Sequence 
DOE MGP Abstracts Online 
Microbial TV Series 
 
Ethical, Legal, and Social Issues and Educational Resources 
Cambridge ELSI Symposium 
Eric Lander, Genetics in the 21st Century 
Mark Rothstein, Genetic Privacy 
James Wilson, Gene Therapy Present & Future 
LeRoy Walters, Ethical Issues in Gene Therapy 
DNA Files on NPR, Internet 
Innovative Biotechnology Curriculum 
Short Course for Biology Teachers 
Microbial TV Series 

Proteomics 
Looking at Proteins to Understand Expression 
2-DGE:  Protein Visualization, Modification 
Tool for Protein Analysis 
TREMBL Release 6 
R&D 100 Award Goes to LANL's SOLVE 
NIH Awards Proteomics Grant to Axys 
E. coli Proteome Database 

Genetics in Medicine 
National Organization for Rare Disorders 
Translation of Genetics to Medicine: New Website 
Cancer Genetics Web Site 
HuGem Website Offers Education in New Genetics 
Calculation of Genetic Risks 2nd Edition 
New Genetics Manual Offered 
Mutation Research Genomics Online 
 
Informatics 
GDB Database Operations Restored 
In Silico Biology: Bioinformatics Journal 
Computational Methods Book Available 
Bioinformatics Guide
BioToolKit
Gene-Finding Programs at Sanger
New Sequin Version
Tandem Repeat Tool
Sequence Viewer
SmithKline Licenses Gene Logic Software 
Influenza Database at LANL 
TRANSFAC Database 
p53 Mutation Database 
TBASE at Jackson Laboratory 
Intein Database on Web 
System Identifies Polymorphisms 

Web, Other Resources, Publications 
1999 Oakland Workshop Website 
Launchpad to Human Chromosomes 
Nature Genetics Supplement 

Funding 
DOE Office of Science Grants and Contracts 
NHGRI National Service Award Fellowships 
NCI Technologies for Molecular Analysis 
NIH: Netork for Large-Scale Mouse Sequencing 
NHGRI: Genomic Technology Development 
US Genome Research Funding 

Meeting Calendars & Acronyms 
Genome and Biotechnology Meetings 
Training Courses and Workshops 
Acronyms 


HGN archives and subscriptions 
HGP Information home

Microbial Genomics News

Unfinished Microbial Genomes Searchable

The National Center for Biotechnology Information (NCBI) Web site links to sequences from unfinished microbial genomes for BLAST searching. These unfinished sequences, which are not yet in GenBank nor accessible via Entrez, also can be retrieved from their associated sequencing centers by ftp or Web. The 18 finished microbial genomes are searchable by Entrez via the NCBI site.


TIGR Releases Chlorobium tepidum Sequence

In September 1998, The Institute for Genomic Research (TIGR) announced the release of more than 1.9 Mb of genome sequence from Chlorobium tepidum, a photosynthetic gram-negative bacterium. The TIGR program, supported by DOE, has reached 3 coverage in the random-sequencing phase. The photosynthetic C. tepidum may play an important role in the earth's overall cycle of carbon use.

Microbial Genome Newsgroup

Microbial-Genomes is a newsgroup for the discussion of microbial (bacterial, archaeal, and small eukaryotic) genomes. To subscribe, send the command subscribe microbial-genomes as the only text in the body of a message.

M. jannaschii Paper Still Hot

The May-June 1998 issue of ScienceWatch, a publication of the Philadelphia-based Institute for Scientific Information, noted that the paper describing the complete genomic sequence of the 1.7-Mb archaeon Methanococcus jannaschii was the fifth most-cited paper in biology for the first 2 months of 1998. The paper, by C.J. Bult and others at The Institute for Genomic Research, confirmed the existence of a third kingdom of life on earth when it appeared in 1996 in Science (273, 1058). At the time of publication, only about one-third of the 1700 genes in M. jannaschii were found to resemble known genes, and the other two-thirds were completely novel to biology. This research was supported by the DOE Microbial Genome Program.

Microbial Information Broker Includes 18

The Genome Information Broker (GIB) now includes 18 microbial genomes that have been sequenced completely and released from DDBJ, EMBL, and GenBank databases. GIB information includes the numbers and names of clones, open reading frames and genes, and sequences. Results are represented in interactive graphics and tables.

UIUC Web Sites Include Microbial Information

Web sites at the University of Illinois at Urbana-Champaign present
  • Sequenced and incomplete genomes, including microbial, found in public databases, with links to sequencing institution, functional overview, publication, and further information.
  • Continuous annotations of Methanococcus jannaschii functions

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).

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