Daniel Hommer, MD, Chief
Section of Brain Electrophysiology and Imaging, LCTS
National Institute on Alcohol Abuse and Alcoholism
National Institutes of Health
10 Center Drive, Room 10-CRC/1E-5330: MSC 1108
Bethesda MD 20892-1108
telephone: 301.402.6094
e-mail: dan.hommer@mail.nih.gov
Dr. Hommer serves as the laboratory chief of the Section of Brain Electrophysiology and Imaging, LCTS, NIAAA . He supervises the scientific research personnel and acts as the scientific leader for the section.
What we do
This section conducts both functional and structural brain imaging studies related to alcoholism. For functional work we primarily use functional magnetic resonance imaging (fMRI) techniques although positron emission tomographic (PET) studies are also undertaken. Structural studies include both measurements of brain volumes using MRI as well as diffusion tensor imaging (DTI). We also use nuclear magnetic resonance (NMR) spectroscopy to measure various brain metabolites. Recently much of our functional work has focused on emotion and motivation as they related to substance abuse. Pharmacological fMRI studies are also employed, particularly studies involving alcohol administration.
Current staff
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Reza Momenan, PhD
Staff Scientist
telephone: 301.451.6972 reza.momenan@mail.nih.gov
Dr. Momenan provides research expertise and support in the areas of experimental design, imaging, and analysis to the SBEI and the Laboratory of Clinical and Translational Studies. His main focus of research is development of image processing and image analysis methods. He also conducts imaging research in both human and animal brain using various methods.
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Dan Rio, PhD
Physicist
telephone: 301.402.2994 dan.rio@mail.nih.gov
Dr. Rio is a physicist/mathematician who setup the original imaging facilities in this section. His current interest is developing new models for analysis of functional MRI in addition to providing support in the areas of computational mathematics, mathematical modeling, image processing and experimental design.
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Beth Israel
Psychologist
telephone: 301.496.7874 beth.israel@mail.nih.gov
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Mike Kerich
Computer Scientist
telephone: 301.496.6540 mike.kerich@mail.nih.gov
Mike Kerich is responsible for providing programming and technical support for the imaging research as well as backing up and maintaining several large servers for imaging data. He also provides desktop support for local users.
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Dasha Dotson
Research Assistant
telephone: 301.594.7416
dasha.dotson@mail.nih.gov
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Betsy Davis
Psychology Technician
telephone: 301.435.3493 betsy.davis@mail.nih.gov
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Jodi Gilman, PhD
Post-Doc IRTA
telephone: 301.451.9401 gilmanj@mail.nih.gov
Dr. Gilman is studying how alcohol affects the neural correlates of emotion. She uses functional magnetic resonance imaging to study both long-term effects of heavy alcohol consumption, as well as acute effects of alcohol administration, on the structure and function of the brain. She is also interested in using neuroimaging to assess the clinical efficacy of medications being developed for alcoholism.
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Tess Crouss
Post-Bacc IRTA
telephone: 301.496.7513 crousstm@mail.nih.gov
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Ashley Smith
Contractor
telephone: 301.451.6978 ashley.smith@mail.nih.gov
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Lawrence Woltz, PhD
Contractor telephone: 301.435.9376
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BEI Clinical Protocols
04-AA-0060 The Effect of Ethanol on Cerebral Blood Flow as Measured by Functional Magnetic Resonance Imaging and the Development of Conditioned Response to Ethanol Administration
03-AA-0013 Brain Activation in Response to Motivational and Affective Stimuli: Pharmacologist Manipulations
98-AA-0009 Screening Evaluation for NIAAA Protocols
98-AA-0056 Functional Neuroanatomy of Positive and Negative Affect in Alcoholics and Nonalcoholics
NIAAA Clinical Protocols & link to all NIH Clinical Protocols
Selected Publications
ORIGINAL PUBLICATIONS
Gilman JM, Hommer DW. Modulation of brain response to emotional images by alcohol cues in alcohol-dependent patients. Addiction Biology, in press. PDF
Bjork JM, Momenan R, Smith A, Hommer DW. Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent patients. Alcohol and Drug Dependence. 95(1-2):115-28, 2008. PDF
Gilman JM, Ramchandani VA , Davis MB , Bjork JM and Hommer DW. Why we like to drink: An fMRI Study of the Rewarding and Anxiolytic Effects of Alcohol. Journal of Neuroscience. 28(18):4583-91, 2008. PDF
George DT, Gilman J, Hersh J, Thorsell A, Herion D, Geyer C, Peng, X, Kielbasa, W, Rawlings, R, Brandt, J, Gehlert DR, Tauscher JT, Hunt SP, Hommer D, Heilig M. Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science. 319(5869):1536-1539, 2008. PDF
Salloum JB, Ramchandani VA, Bodurka J, Rawlings R, Momenan R, George D, Hommer DW. Blunted rostral anterior cingulate response during a simplified decoding task of negative facial expressions in alcoholic patients. Alcoholism: Clinical and Experimental Research. 31(9): 1490-1504, 2007. PDF
Bjork JM, Smith A, Danube C, Hommer DW. Developmental differences in posterior mesofrontal cortex recruitment by risky rewards. Journal of Neuroscience. 27(18): 4839-4849, 2007. PDF
Schottenbauer MA, Momenan R, Kerich M, Hommer DW. Relationships among aging, IQ, and intracranial volume in alcoholics and control subjects. Neuropsychology. 21(3): 337-345, 2007. PDF
Schottenbauer MA, Hommer D, Weingartner H. Memory deficits among alcoholics: Performance on a selective reminding task. Aging, Neuropsychology, and Cognition. 14(5): 505-516, 2007. PDF
Brown AK, George DT, Fujita M, Liow J, Ghose S, Sangare J, Hommer DW, Innis RB. PET [11C]DASB imaging of serotonin transporters in patients with alcoholism. Alcoholism: Clinical and Experimental Research. 31(1): 28-32, 2007. PDF
Gilman JM, Bjork JM, Hommer DW. Parental alcohol use and brain volumes in early- and late-onset alcoholics. Biological Psychiatry. 62(6):607-615, 2007. PDF
Bjork JM, Hommer DW. Anticipating instrumentally obtained and passively-received rewards: A factorial fMRI investigation. Behavioural Brain Research. 177 (1): 165-170, 2007. PDF
Rio DE, Rawlings RR, Woltz LA, Salloum JB, Hommer DW. Single subject image analysis using complex general linear model - An application to functional magnetic imaging with multiple inputs. Computer Methods and Programs in Biomedicine. 82(1):10-19, 2006. PDF
Momenan R, Rawlings R, Fong G, Knutson B, Hommer D. Voxel-based homogeneity probability maps of gray matter in groups: assessing the reliability of functional effects. Neuroimage. 21(3):965-72, 2006. PDF
Bjork JM, Hommer DW, Grant SJ, Danube C. Impulsivity in abstinent alcohol-dependent patients: relation to control subjects and type 1-/type 2-like traits. Alcohol 2004; 42 (2-3): 133-150. PDF
Knutson B, Bjork JM, Fong GW, Hommer D, Mattay VS, Weinberger DR. Amphetamine modulates human incentive processing. Neuron. 43 (2):261-269, 2004 July . PDF
Bjork JM, Knutson B, Fong GW, Caggiano DM, Bennett SM, Hommer DW. Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J Neurosci . 24(8):1793-1802, 2004 February. PDF
Bjork JM, Grant SJ, Hommer DW. Cross-sectional volumetric analysis of brain atrophy in alcohol dependence: effects of drinking history and comorbid substance use disorder. Am J Psychiatry. 160(11):2038-45, 2003 November. PDF
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NIH Research and Training Opportunities
Updated: July 2008
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