Agency for Toxic Substances and Disease Registry
Case Studies in Environmental Medicine (CSEM) 

Lead Toxicity
Literature Cited

References

1. Agency for Toxic Substances and Disease Registry. 1999. Toxicological profile for lead. Atlanta: US Department of Health and Human Services, Public Health Service.
2. Agency for Toxic Substances and Disease Registry. 2005. Toxicological profile for lead. Atlanta: US Department of Health and Human Services, Public Health Service.
3. Alexander H, Checkoway H, van Netten C, et al. 1996. Semen quality of men employed at a lead smelter. Occup Environ Med 53:411-416.
4. Alexander FW, Clayton BE, Delves HT. 1974. Mineral and trace-metal balances in children receiving normal and synthetic diets. QJ Med 43:89-11.
5. American Academy of Pediatrics. 1993. Lead poisoning: from screening to primary prevention. Pediatrics 92(1): 176-183.
6. American Academy of Pediatrics. 1995. Treatment guidelines for lead exposure in children. Pediatrics 96(1): 155-1601.
7. American Conference of Governmental Industrial Hygienists (ACGIH) 2005. TLVs and BEIs. 2005. Signature publications. Cincinnati, OH.
8. Aufderheide AC, Wittmers LE Jr. 1992. Selected aspects of the spatial distribution of lead in bone. Neurotoxicol 13:809-820.
9. Baghurst PA, Robertson EF, McMichael AJ, et al. 1987. The Port Pirie cohort study: lead effects on pregnancy outcome and early childhood development. Neurotoxicology 8:395-401.
10. Barry PSI. 1981. Concentrations of lead in the tissues of children. Br J Ind Med 38:61-71.
11. Batuman V, Maesaka JK, Haddad B, Medicaid et al. 1981. The role of lead in gout nephropathy. New England Journal of Medicine 304:520-3.
12. Bennett WM. 1985. Lead nephropathy. Kidney Int 28:212-20.
13. Borja-Aburto, et al. 1999. Blood Lead Levels Measured Prospectively and Risk of Spontaneous Abortion. Am J Epidemiol 1999; 150:590-7
14. Bowen WH. 2001. Exposure to metal ions and susceptibility to dental caries. Journal of Dental Education. 65(10): 1046-1053.
15. Buchanan LH, Counter SA, Ortega F, Laurell G. 1999. Distortion product oto-acoustic emissions in Andean children and adults with chronic lead intoxication. Acta Otolaryngol. 1999; 119(6):652-8.
16. Budd P, Montgomery J, Cox A, Krause P, Barreiro B, Thomas RG. 1998. The distribution of lead within ancient and modern human teeth: implications for long-term and historical exposure monitoring, Sci Total Environ (Sept) 18;220(2-3):121-36.
17. Canfield RL, Henderson CR, Cory-Slechta DA, Cox C, Juski TA, Lanphear BP. 2003. Intellectual impairment in children with blood lead concentrations below 10 µg per Deciliter. New England Journal of Medicine. 348(16): 1517-1526.
18. Centers for Disease Control and Prevention. 1997a. Screening young children for lead poisoning: guidance for state and local public health officials. Atlanta: US Department of Health and Human Services, Public Health Service, CDC Childhood Lead Poisoning Prevention Program. November 1997.
19. Centers for Disease Control and Prevention. 1997b. Update: blood lead levels. MMWR 46(7)141-146.
20. Centers for Disease Control and Prevention. 2002. Managing elevated blood lead levels among young children: Recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention. Atlanta: US Department of Health and Human Services.
21. Centers for Disease Control and Prevention. 2003. Surveillance for Elevated Blood Lead Levels Among Children --- United States, 1997—2001. Atlanta: US Department of Health and Human Services. September 12, 2003 / 52(SS10);1-21. Available from URL: http://www.cdc.gov/mmwr/preview/mmwrhtml/ss5210a1.htm.
22. Centers for Disease Control and Prevention 2005. Blood lead levels- Unites States 1999-2002. MMWR 54(20)513-516.
23. Chamberlain A, Heard C, Little MJ, et al. 1978. Investigations into lead from motor vehicles. Harwell, United Kingdom: United Kingdom Atomic Energy Authority. Report no. AERE-9198. 1979. The dispersion of lead from motor exhausts. Philos Trans R Soc Lond A 290:557-589.
24. Children’s Environmental Health Network (CEHN). 1999. Training manual on pediatric environmental health: Putting it into practice. Available from URL: www.cehn.org/cehn/trainingmanual/manual-front.html.
25. Cooper WC. 1976. Cancer mortality patterns in the lead industry. Ann NY Acad Sci 271:250-259.
26. DeSilva PE. 1981. Determination of lead in plasma and studies on its relationship to lead in erythrocytes. Br J Ind Med 38:209-217.
27. EPA. 1986a. Air quality criteria for lead. Research Triangle Park, NC: U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment. Environmental Criteria and Assessment Office. EPA 600/8-83-028F.
28. EPA. 1986b. Determination of reportable quantities for hazardous substances. U.S. Environmental Protection Agency. Code of Federal Regulations. 40 CFR 117.
29. Ernhart CB, Wolf AW, Kennard MJ, et al. 1985. Intrauterine lead exposure and the status of the neonate. In: Lekkas TD, ed. International Conference on Heavy Metals in the Environment, Athens, Greece. September, Vol. 1. Edinburgh, United Kingdom: CEP Consultants, Ltd. 35-37.
30. Everson J, Patterson CC. 1980. “Ultra-clean” isotope dilution/mass spectrometric analyses for lead in human blood plasma indicate that most reported values are artificially high. Clin Chem 26:1603-1607.
31. FDA. 1994. Action Levels for Poisonous or Deleterious Substances in Human Food and Animal Feed. Department of Health and Human Services. Public Health Service. Food and Drug Administration.
32. FDA. 1995. Substances prohibited from use in human food. Substances prohibited from indirect addition to human food through food-contact surfaces. U.S. Food and Drug Administration. Code of Federal Regulations. 21 CFR 189.240.
33. Flegal AR and Smith DR.1995. Measurements of environmental lead contamination and human exposure. Rev Environ Contam Toxicol 143:1-45.
34. Fulton M, Raab G, Thomson G, Laxen D, Hunter R, Hepburn W. 1987. Influence of blood lead on the ability and attainment of children in Edinburgh. Lancet 1: 1221-1226.
35. Gennart J-P, Buchet J-P, Roels H, et al. 1992. Fertility of male workers exposed to cadmium, lead or manganese. Am J Epidemiol 135: 1208-1219.
36. Goyer RA. 1985. Renal changes associated with lead exposure. In: Mahaffey KR, rd. Dietary and environmental lead: Human health effects. Amsterdam, The Netherlands: Elsevier Science Publishers B.V.
37. Griffin TB, Couiston F, Wills H. 1975. Biological and clinical effects of continuous exposure to airborne particulate lead. Arh Hig Toksikol 26:191-208. (Yugoslavian)
38. Hawk BA, Schroeder SR, Robinson G, et al. 1986. Relation of lead and social factors to IQ of low SES children: a partial replication: Am J Ment Defic 91:178-183.
39. Hu H. 1991. Knowledge of diagnosis and reproductive history among survivors of childhood plumbism. Am J Public Health 81:1070-1072.
40. Hu H, Aro A, Payton M, et al. 1996. The relationship of bone and blood lead to hypertension. The normative aging study. JAMA 275:1171-6.
41. IARC. 1987. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: Overall evaluations of carcinogenicity. Suppl 7: An updating of the IARC monographs volumes 1 to 42. Lyon, France: World Health Organization, International Agency for Research for Research on Cancer, 230-232.
42. James HM, Milburn ME, Blair JA. 1985. Effects of meals and meal times on uptake of lead from the gastrointestinal tract of humans. Human Toxicol 4:401-407.
43. Kaul B, Sandhu RS, Depratt C, and Reyes F. 1999. Follow-Up Screening of Lead-Poisoned Children Near an Auto Battery Recycling Plant, Haina, Dominican Republic. Environ Health Perspect 107:917-920.
44. Kehoe RA. 1961. The metabolism of lead in man in health and disease: Present hygienic problems relating to the absorption of lead: The Harben lectures, 1960. J R Inst Public Health Hyg 24:177-203.
45. Kim R, Rotnitzky A, Sparrow D, et al. 1996. A longitudinal study of low-level lead exposure and impairment of renal function. The normative aging study. JAMA 275:1177-81.
46. Koo WWR, Succop PA, Bornschcin RL, et al. 1991. Serum vitamin D metabolites and bone mineralization in young children with chronic low to moderate lead exposure. Pediatrics 87:680-687.
47. Korrick SA, Hunter DJ, Rotnitzky A, et al. 1999. Lead and hypertension in a sample of middle-aged women. Am J Public Health. 89(3): 330-5.
48. Landrigan PJ, Schechter CB, Lipton JM, Fahs MC, and Schwartz J. 2002. Environmental pollutants and disease in American children: Estimates of morbidity, mortality, and costs for lead poisoning, asthma, cancer, and developmental disabilities. Environmental Health Perspectives. 110(7): 721-728.
49. Landsdown R, Yule W, Urbanowicz MA, Hunter J. 1986. The relationship between blood-lead concentrations, intelligence, attainment and behavior in a school population: the second London study. Int Arch Occup Environ Health 57: 225-235.
50. Lanphear BP, Matte TD, Rogers J, Clickner RP, Dietz B, Bornschein RL, Succop P,
51. Mahaffey KR, Dixon S, Galke W, Rabinowitz R, Farfel M, Rohde C, Schwartz J, Ashley P, and Jacobs DE. 1998. The contribution of lead-contaminated house dust and residential soil to children’s blood lead levels: A pooled analysis of 12 epidemiological studies. Environmental research 79: 51-68.
52. Lanphear BP, Dietrich K, Auinger P, Cox. C 2000. Cognitive deficits associated with BLLs <10 µg/dL in US children and adolescents. Public Health Rep. 115:521-529.
53. Lanphear BP, Hornung R, Ho M, Howard CR, Eberley S, and Knauf K. 2002. Environmental lead exposure during early childhood. Journal of Pediatrics 140: 40-47.
54. Lerda D. 1992. Study of sperm characteristics in persons occupationally exposed to lead. Am J Ind Med 22:567-571.
55. Lin S, Hwang S, Marshall EG, et al. 1996. Fertility rates among lead workers and professional bus drivers: A comparative study. Ann Epidemiol 6:201-208.
56. Litvak PF, Wasserman G, Kline JK, Jgraziano. 1999. The Yugoslavia Prospective Study of Environmental Lead Exposure. Environ Health Perspect 107:9-15.
57. López-Carrillo L, Torres-Sánchez L, Garrido F, Papaqui-Hernández J, Palazuelos-Rendón E, López-Cervantes M. 1996. Prevalence and determinants of lead intoxication in Mexican children of low socioeconomic status. Environ Health Perspect 104:1208-1211.
58. Mahaffey KR. 1990. Environmental lead toxicity: nutrition as a component of intervention. Environ Health Perspect 89:75-78.
59. McMichael AJ, Vimpani GV, Robertson EF, et al. 1986. The Port Pirie cohort study: Maternal blood lead and pregnancy outcome. J Epidemiol Community 40:18-25.
60. Murphy MJ, Graziano JH, Popovac D, et al. 1990. Past pregnancy outcomes among women living in the vicinity of a lead smelter in Kosovo, Yugoslavia. Am J Public Health 80:33-5.
61. Mushak P, Davis JM, Crocetti AF, Grant LD. 1989. Prenatal and postnatal effects of low-level lead exposure: integrated summary of a report to the US Congress on childhood lead poisoning. Environ Res 50:11-36
62. National Center for Healthy Housing (NCHH). 2001. Another link in the chain: State policies and practices for case management and environmental investigation for lead poisoned children: Update. Columbia, MD.
63. National Toxicology Program (NTP) 2004. Lead (CAS No. 7439-92-1) and lead compounds. Report on carcinogens, eleventh edition.
64. Needleman HL, Rabinowitz M, Leviton A, et al. 1984. The relationship between prenatal exposure to lead and congenital anomalies. JAMA 251:2956-2959.
65. Needleman H.L. 2002. Bone lead levels in adjudicated delinquents: A case control study. Neurotoxicology and Teratology 24: 711-717.
66. Nevin R. 2000. How lead exposure relates to temporal changes in IQ, violent crime, and unwed pregnancy.
67. Nordstrom S, Beckman L, Nordenson I. 1979. Occupational and environmental risks in and around a smelter in northern Sweden. V. Spontaneous abortion among female employees and decreased birth weight in their offspring. Hereditas 90:291-6.
68. Payton M, Hu H, Sparrow D, et al. 1994. Low-level lead exposure and renal function in the normative aging study. Am J Epidemiol 140(9):821-9.
69. Puzas JE, Sickel MJ, Felter ME. 1992. Osteoblasts and chondrocytes are important target cells for the toxic effects of lead. Neurotoxicology 13:800-806.
70. Rabin R.Warnings unheeded: a history of child lead poisoning. 1989. Am J Publ Health. 79:1668-1674.
71. Rabinowitz MB, Wetherill GW, Kopple JD. 1976. Kinetic analysis of lead metabolism in healthy humans. J Clin Invest 58:260-270.
72. Rothenberg SJ, Karchmer S, Schnaas L, Perroni E, Zea F, and Alba JF. 1994. Changes in serial blood lead levels during pregnancy. Environ Health Perspect 102: 876-880.
73. Saper RB, Kales SN, Paquin J, Burns MJ, Eisenberg DM, Davis RB, Phillips RS. 2004. Heavy metal content of Ayurvedic herbal medicine products. JAMA. 292(23): 2868-2873.
74. Sayre JW, Charney E, Vostal J, Pless BI. 1974. House and hand dust as potential source of childhood lead exposure. Am J Dis Child. 127:167-170.
75. Schwartz J. 1995. Lead, blood pressure, and cardiovascular disease in men. Arch Environ Health 50:31-37.
76. Schroeder SR, Hawk B, Otto DA, Mushak P, Hicks RE. 1985. Separating the effects of lead and social factors on IQ. Environ Res 38:144-154.
77. Staessen JA, Lauwerys RR, Buchet JP, et al. 1992. Impairment of renal function with increasing blood lead concentrations in the general population. N Engl J M 327(3): 151-6.
78. Telisman S, Cvitkovic P, Jurasovic J, Pizent A, Gavella M, Rocic B. 2000. Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men. Environ Health Perspect 108:45-53.
79. Victery W, Throler HA, Volpe R, et al. 1988. Summary of discussion sessions: Symposium on lead blood pressure relationships. Environ Health Perspect 78:139-155.
80. Wasserman GA, Liu X, Lolacono NJ, Factor-Litvak P, Kline JK, Popovac D, Morina N, Musabegovic A, Vrenezi N, Capuni-Paracka S, Lekic V, Preteni-Redjepi E, Hadzialjevic S, Slavkovich V, Graziano JH. 1997. Lead exposure and intelligence in 7-year-old children: the Yugoslavia prospective study. Environ Health Perspect 105:956-962.
81. Watson GE, Davis BA, Raubertas RF, Pearson SK, Bowen WH. 1997. Influence of maternal lead ingestion on caries in rat pups, Nat Med 3(9): 1024-1025. 
82. Weeden RP, D’Haese P, Van de Vyver FL, et al. 1986. Lead nephropathy. Am J Kidney Dis 3(5): 380-3.
83. Winneke G, Brockhaus A, Ewers U, Kramer U, Neuf M. 1990. Results from the European multicenter study on lead neurotoxicity in children: implications for risk assessment. Neurotoxicol Teratol 12:553-559.
84. Yule W, Lansdown R, Millar IB, Urbanowicz MA. 1981. The relationship between blood lead concentrations, intelligence and attainment in a school population: a pilot study. Dev Med Child Neurol 23:567-576
85. Ziegler EE, Edwards BB, Jensen RL, et al. 1978. Absorption and retention of lead by infants. Pediatr Res 12:29-34.