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Ensuring the safety of our Nation’s roads requires addressing the increase in fatalities involving large trucks and buses. One key area of addressing motor carrier safety is to ensure that commercial drivers maintain a valid medical certificate, which confirms they are healthy enough to safely operate the commercial vehicle. Our office is initiating an audit of the Federal Motor Carrier Safety Administration’s (FMCSA) oversight processes and controls for the medical certificate program and the quality of data submitted to the medical certificate database. Our objectives for this self-initiated audit are to evaluate FMCSA’s procedures for (1) oversight of its medical certificate program, including commercial driver medical certificate data quality, and (2) validating information in its National Registry of Certified Medical Examiners.