National Center for Medical Rehabilitation Research (NCMRR)

We are interested in applications that align with the following research priorities. For more information about NICHD’s research themes and cross-cutting topics, see NICHD Strategic Plan 2020 (PDF 2.3 MB).

Person-Centered Measures, Real-World Outcomes

Strategic Plan Theme 5: Advancing Safe and Effective Therapeutics and Devices for Pregnant and Lactating Women, Children, and People with Disabilities

Gap: Many rehabilitation outcome measures are targeted to clinic- or hospital-based assessments and do not reflect the person’s perception of their function across the rehabilitation process.

Priority: Research to develop scalable strategies and technologies to monitor person-centered outcomes. This approach includes the use of mobile technologies and social and behavioral science to understand the person’s perception of progress, their perception of environmental supports and barriers, their level of participation, and level of independence. Use large-scale datasets and big data approaches to measure exposure responses to therapy and device use among people with disabilities.

Multimodal Approaches to Promote Plasticity and Sensorimotor Function

Strategic Plan Theme 5: Advancing Safe and Effective Therapeutics and Devices for Pregnant and Lactating Women, Children, and People with Disabilities

Gap: Many rehabilitation interventions are multimodal, but there are few funded studies that target combination therapies.

Priority: Research on multimodal approaches that promote plasticity and sensorimotor function, particularly the combination of physical therapy with regenerative, pharmacological, or stimulation treatments. These projects may require team science approaches with multidisciplinary researchers.

Objective Markers of Treatment Response and Functional Progress

Strategic Plan Theme 5: Advancing Safe and Effective Therapeutics and Devices for Pregnant and Lactating Women, Children, and People with Disabilities

Gap: Rehabilitation outcomes are difficult to predict and measure objectively.

Priority: Research to develop objective measures of rehabilitation treatment response and functional progress. Promote discovery of biomarkers that predict rehabilitation treatment response and enable the tailoring of interventions to the needs, abilities, and resources of the person with disability. Identify new modeling approaches and better outcome measures to support the use of pharmacotherapies combined with rehabilitation strategies to reduce the barriers to testing for adults and children with physical disabilities.

Prevention and Treatment of Secondary Conditions

Strategic Plan Cross-Cutting Topic: Disease Prevention

Gap: There is a limited understanding of the incidence and prevalence of secondary conditions (e.g., pain, musculoskeletal dysfunction, deconditioning, skin breakdown, cognitive impairment, behavioral/social/emotional difficulties, and sleep disturbances) among individuals with physical disability; similarly, there are relatively few targeted strategies to prevent or treat these conditions.

Priority: Research to identify, prevent, and treat key secondary conditions that are associated with physical impairments and disabilities. This includes the role of rehabilitation approaches and self-management techniques for individuals and families.

Transition to Adulthood

Strategic Plan Theme 4: Improving Child and Adolescent Health and the Transition to Adulthood

Gap: The field lacks data on the types of interventions, services, and outcome assessments needed to ensure successful transition from pediatric rehabilitation care to general medical services.

Priority: Research aimed at improving the transition to adult health care for young adults with physical disabilities. Develop measures that may help determine successful transition at the individual, provider, or system level to improve care for adolescents. Develop rehabilitation pathways to optimize recovery for children who experience critical illness and/or traumatic injury.  

• Adaptation and Plasticity
• Devices and Technology Development
• Rehabilitation Diagnostics and Interventions
• Chronic Symptom Management
• Health Services Research
• Environmental Factors

• Medical Rehabilitation Research Resource Network (MRRRN)
• Rehabilitation Research Career Development (RRCD) Program

• Theresa Cruz, Director
• Toyin Ajisafe, Health Scientist Administrator
  Grant Categories: Rehabilitation devices and technology development; rehabilitation diagnostics and interventions
• Joe Bonner, Health Scientist Administrator
  Grant Categories: Adaptation and plasticity; rehabilitation diagnostics and interventions
• Sue Marden, Health Scientist Administrator
  Grant Categories: Rehabilitation diagnostics and interventions; chronic symptom management in rehabilitation; rehabilitation health services research; environmental factors affecting rehabilitation
• Ralph Nitkin, Health Scientist Administrator
  Grant Categories: Rehabilitation training and career development; adaptation and plasticity
• Alicia Ross, Program Analyst
• Shawnise Durham, Administrative Assistant
• Eliza Polk, Administrative Assistant
• Elizabeth Wilson, Contractor