Bureau of International Security and Nonproliferation
Office of Multilateral Nuclear and Security Affairs
Our Mission
The Office of Multilateral Nuclear and Security Affairs (ISN/MNSA) leads Department of State formulation and implementation of U.S. policy relating to the global nuclear nonproliferation regime, especially the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), the NPT review process, the International Atomic Energy Agency (IAEA), Nuclear-Weapon-Free-Zone treaties and protocols, and nuclear-related security assurances.