Laboratory Tests

This section focuses on FDA-approved diagnostic HIV tests for use in moderate and high complexity laboratories.

Laboratory Testing Guidance

• 2018 Quick Reference Guide: Recommended laboratory HIV testing algorithm for serum or plasma specimens
• Updated January 2019  APHL Suggested Reporting Language for the HIV Laboratory Diagnostic Testing Algorithmpdf iconexternal icon
• Full Version of the Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations
• Technical Update on HIV-1/2 Differentiation Assays, August 2016
• Technical Update: Use of the Determine HIV 1/2 Ag/Ab Combo Test with Serum or Plasma in the Laboratory Algorithm for HIV Diagnosis

FDA Approved HIV Tests

• Advantages and Disadvantages of Different Types of HIV tests pdf icon[PDF – 236 KB]
• Laboratory Screening Tests pdf icon[PDF – 602 KB]
• Updated February 2019 Supplemental Tests for Laboratory Settings pdf icon[PDF – 456 KB]
• Moderate Complexity Rapid HIV Tests for Clinical Settings pdf icon[PDF – 173 KB]
• CLIA-waived rapid HIV tests pdf icon[PDF – 619 KB]

Resources

• Fact Sheet: False Positive HIV Test Results pdf icon[PDF – 130 KB]
• Selecting an HIV Test: A Narrative Review for Clinicians and Researchersexternal icon
• The Evolution of HIV Testing Continuesexternal icon
• Highlights from the 2016 HIV diagnostics conference: The new landscape of HIV testing in laboratories, public health programs and clinical practiceexternal icon
• New HIV Testing Technologies: Implications for your Laboratoryexternal icon
• Association of Public Health Laboratories (APHL) HIV Testing Resourcesexternal icon (includes recent manufacturer news)
• Detection of Acute HIV Infection in Two Evaluations of a New HIV Diagnostic Testing Algorithm — United States, 2011–2013
• 2013 Journal of Clinical Virology Supplement: HIV Laboratory Diagnosis: New Tests and a New Algorithmexternal icon.
  (Select year 2013 then Vol. 58 December, 2013 p.e1-e134-Supplement 1)
• HIV Diagnostics Conferenceexternal icon