See comment in PubMed Commons belowBMJ. 2008 Apr 26;336(7650):924-6. doi: 10.1136/bmj.39489.470347.AD.
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.
Alderson P, Alonso-Coello P, Andrews J, Atkins D, Bastian H, de Beer H, Brozek J, Cluzeau F, Craig J, Djulbegovic B, Falck-Ytter Y, Fervers B, Flottorp S, Glasziou P, Guyatt G, Harbour R, Haugh M, Helfand M, Helfand M, Jaeschke R, Jones K, Kunnamo I, Kunz R, Liberati A, Marzo M, Mason J, Mrukovics J, Norris S, Oxman A, Robinson V, Schünemann H, Tan Torres T, Tovey D, Tugwell P, Tuut M, Varonen H, Vist G, Wittington C, Williams J, Woodcock J.
- 1Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5. guyatt@mcmaster.ca
In making healthcare management decisions, patients and clinicians must weigh up the benefits and downsides of alternative strategies. Decision makers will be influenced not only by the best estimates of the expected advantages and disadvantages but also by their confidence in these estimates. The cartoon depicting the weather forecaster’s uncertainty captures the difference between an assessment of the likelihood of an outcome and the confidence in that assessment (figure). The usefulness of an estimate of the magnitude of intervention effects depends on our confidence in that estimate.
BMJ. 2008 Apr 26;336(7650):924-926.
Full Text Sources
Other Literature Sources
Medical