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Grantees in the News
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An Unexpected Role for the Brain’s Immune Cells
Gladstone InstituteMonday, December 14, 2020
In a recent study published in the journal Nature Neuroscience, Gladstone Institute researchers show that surveillance by microglia helps prevent seizure activity (or hyperexcitability) in the brain.
Damage to brain cells reverberates to ‘bystander’ cells, study finds
Oregon Health & Sciences UniversityTuesday, December 8, 2020
OHSU scientists are first to document mechanism that can cause temporary but severe loss of nervous system function.
How the brain remembers right place, right time
UT Southwestern Medical CenterTuesday, December 8, 2020
Studies could lead to new ways to enhance memory for those with traumatic brain injury or Alzheimer’s disease.
What scientists are learning about COVID-19 and the brain
Sanford Burnham PrebysTuesday, December 8, 2020
Brain fog. Memory loss. Dizziness and confusion. Although COVID-19 is primarily thought of as a lung disease, survivors continue to report lingering and highly concerning neurological effects—severe enough to impact their ability to work and live normal lives.
A role for the slow oscillations of the neocortex in epileptic spasm generation
Baylor College of Medicine and Texas Children’s HospitalMonday, December 7, 2020
Researchers from Baylor College of Medicine and Texas Children’s Hospital now provide evidence that epileptic spasms originate from the pyramidal cells in the deep layers of the neocortex. Further, they uncovered a novel neurophysiological phenomenon that explains how cortical neurons generate spasms.
Novel form of Alzheimer’s protein found in spinal fluid indicates stage of the disease
Washington University School of Medicine in St. LouisMonday, December 7, 2020
Discovery could lead to better diagnostics, speed efforts to find treatment.
Novel gene variants that modify risk of late-onset Alzheimer’s disease discovered
Baylor College of Medicine and Texas Children’s HospitalMonday, December 7, 2020
Researchers at Baylor College of Medicine and Texas Children’s Hospital have now identified more than 200 new gene variants believed to play a role in who is affected by Late-onset Alzheimer’s disease (LOAD).
Research unlocks new information about reading through visual dictionary in the brain
The University of Texas Health Science Center at HoustonMonday, November 30, 2020
Scientists at The University of Texas Health Science Center at Houston (UTHealth) have now identified a crucial region in the temporal lobe, know as the mid-fusiform cortex, which appears to act as the brain’s visual dictionary.
Genetic treatment plus exercise reverses fatigue in mice with muscle wasting disease
Massachusetts General HospitalMonday, November 30, 2020
Adding exercise to a genetic treatment for myotonic dystrophy type 1 (DM1) was more effective at reversing fatigue than administering the treatment alone in a study using a mouse model of the disease. In fact, exercise alone provided some benefit whereas the genetic treatment alone did not.
Cortex over reflex: Study traces circuits where executive control overcomes instinct
The Picower Institute for Learning and Memory at MITMonday, November 30, 2020
When riding your bike to the store you might have two very different reasons to steer: plain old reflex when you see something dart into your path, or executive control when you see street signs that indicate the correct route. A new study by MIT neuroscientists shows how the brain is wired for both by tracking the specific circuits involved and their effect on visually cued actions.
