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Alternatives Literature Searching

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The regulations of the AWA require that investigators provide Institutional Animal Care and Use Committees (IACUCs) with documentation demonstrating that alternatives to procedures that may cause more than momentary pain or distress to the animals have been considered and that activities do not unnecessarily duplicate previous experiments. A thorough literature search regarding alternatives using relevant sources helps to meet this Federal mandate. 
AWIC Tips for Searching for Alternatives to Animal Research and Testing

USDA. NAL. Animal Welfare Information Center.

The following guidelines were developed to assist researchers, information specialists, and Institutional Animal Care and Use Committee (IACUC) members, when conducting literature searches to determine if alternatives to the use of animals exist and whether a protocol unnecessary duplicates previous research.

Databases

USDA. NAL. Animal Welfare Information Center.

Databases containing information on biomedical research, biological science, animal science, veterinary medicine, fish and wildlife research, toxicology and specialized alternative (3R) methods.