K99/R00 - The Pathway to Independence Award
The NIH Pathway to Independence Award (K99/R00) helps outstanding postdoctoral researchers complete needed mentored training and transition in a timely manner to independent, tenure-track or equivalent faculty positions.
NCI will accept K99/R00 applications in all areas of cancer research.
Reference the Program Announcements PA-20-187 (K99/R00 - Independent Clinical Trial Required) , PA-20-188 (K99/R00 - Independent Clinical Trial Not Allowed), and PA-20-189 (K99/R00 - Independent Basic Experimental Studies with Humans Required) or contact the program staff.
Applicant Eligibility
Citizens, Foreign Nationals, and U.S. Visa Holders |
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Geographic Location | K99/R00 recipients must reside in and work at U.S.-based institutions for the duration of the award. |
Career Stage |
Postdoctoral and Clinical Fellows
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Commitment | Candidate must commit a minimum of 9 calendar months (75%) full-time professional effort to the K99/R00 Career Development Award |
Duration of Award |
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R00 Criteria
Citizens, Foreign Nationals, and U.S. Visa Holders | For the R00 phase of the award, the U.S institution at which the R00 phase of the award will be conducted is responsible for determining and documenting, in the R00 application, that the PD/PI's visa will allow the PD/PI to remain in the U.S. for the duration of the R00 Award. |
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Geographic Location | R00 recipients must reside in and work at U.S. based institutions for the duration of the award. |
Career Stage | Tenure-track full-time assistant professor position (or equivalent) offered and accepted |
Institutional Commitment |
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Duration of Award | R00 phase: Up to 3 years |
Transition Application |
The independent phase institution should submit an application on behalf of the candidate for the R00 Award using the PHS 398 Application no later than 2 months prior to the proposed activation date of the R00 Award.
Human Subjects If the proposed research involves human subjects, provide:
Vertebrate Animals If the proposed research involves vertebrate animals, provide:
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Application Due Date | At least 2 months prior to the proposed activation date of the R00 Award |
Budget
Financial Support
K99 Phase | |
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Salary Support** | Up to $100K/year + fringe benefits |
Research Development Support: Research and Career Development Activities | Up to $30K/year |
F&A Costs/Indirect Costs | 8% |
Ancillary Personnel Support: Salary for Mentors, Secretarial and Administrative Assistance, etc. | Not allowed |
R00 Phase | |
Salary Research Development Support: Research and Career Development Activities F&A/ Indirect Costs | Up to $249K/year |
Ancillary Personnel Support: Salary for Mentors, Secretarial and Administrative Assistance, etc. | Not allowed |
Salary for Postdoctoral, Technician, Lab Manager Support | Allowed |
** The requested salary must be consistent with a) the established salary structure at the institution and b) with salaries actually provided by the institution from its own funds to other staff members with equivalent qualifications, rank, and responsibilities in the department concerned.
How to Apply
- Applications must submitted electronically.
- Applicants must follow the instructions in the SF424 (R&R) Application Guide, as well as any program-specific instructions in section IV of the Program Announcement.
- When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.
- Applications that do not comply with these instructions may be delayed or not accepted for review.
For assistance with application submission, please see the Frequently Asked Questions and/or contact eRA Commons Help Desk/Grant.gov contact Center.
Application Receipt Dates and Review Schedule
Receipt Cycle | Receipt Date: New Application | Receipt Date: Resubmission | Initial Review | Council Review | Earliest Possible Start Date* |
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1 | February 12 | March 12 | June/July | September/October | December |
2 | June 12 | July 12 | October/November | January/February | April |
3 | October 12 | November 12 | February/March | May/June | July |
* Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.
Applications are due by 5 pm local time.
When a standard submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.
Review and Selection Process
Subcommittee I, convened by the Division of Extramural Activities of the NCI, will determine if it meets the broad needs of the program and priorities of NCI and the National Cancer Program.
For review criteria for the K99 grant mechanism, see Section V. Application Review Information of the Program Announcement.
NCI Special Notes
Data Sharing
Under the NIH Data Sharing Policy, grantees are expected to engage in a timely release of final data sets that have been generated with NIH support for use by other researchers, provide a Data Sharing Plan that will achieve this objective, OR state why data sharing is not possible or appropriate.
Resources
- Program Announcement PA-20-187 (K99/R00 - Independent Clinical Trial Required)
- Program Announcement PA-20-188 (K99/R00 - Independent Clinical Trial Not Allowed)
- Program Announcement PA-20-189 (K99/R00 - Independent Basic Experimental Studies with Humans Required)
- Current List of K99/R00 Awards
- Link to Main Peer Review Group NCI-I
- K99/R00 FAQ
- Training Funding Opportunities to Promote Diversity
- Overview of the Grant Process
- NCI Resources for Researchers
- NIH Grants Policy Statement (GPS)- see section 12
NCI Staff Contacts
For additional information regarding policies and/or guidance in preparing an application for the K99/R00 Award, contact:
- Branch Phone: 240-276-5630
- Dr. Michael Schmidt
Program Director
Email: mschmidt@mail.nih.gov - Dr. Sergey Radaev
Program Director
Email: sradaev@mail.nih.gov
For information regarding fiscal and/or budget issues, contact:
- Grant Management Contact
Mutema Nyankale - Email: mutema.nyakale@nih.gov
For information regarding referral and review issues, contact:
- Referral Officer
Division of Extramural Activities
Phone: 240-276-6390
Fax: 240-276-7682