Click on the links below or scroll down to view open opportunities in each section.
- Requests for Applications
- Requests for Information (when available)
- Program Announcements
- Notices
- Challenges (when available)
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Research
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Open Opportunities
Requests for Applications
NIH Blueprint for Neuroscience Research: Functional Neural Circuits of Interoception (R01, Clinical Trial Not Allowed)
RFA-AT-21-003 · Posted Date: 09/02/2020Urgent Phase I/II Clinical Trials to Repurpose Existing Therapeutic Agents to Treat COVID-19 Sequelae (U01 Clinical Trial Required)
RFA-TR-20-003 · Posted Date: 08/05/2020Ethical Issues in Translational Science Research (R01 Clinical Trial Optional)
RFA-TR-20-001 · Posted Date: 10/23/2019HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
RFA-NS-20-009 · Posted Date: 10/03/2019HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)
RFA-NS-20-011 · Posted Date: 10/01/2019Program Announcements
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
PA-21-071 · Posted Date: 11/16/2020Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
PA-20-272 · Posted Date: 10/09/2020Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
PA-20-275 · Posted Date: 10/06/2020Drug Development Collaboratory (UG3/UH3 Clinical Trial Required)
PAR-20-301 · Posted Date: 09/18/2020Research to Improve Native American Health (R21 Clinical Trials Optional)
PAR-20-214 · Posted Date: 08/17/2020SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed)
PAR-20-128 · Posted Date: 07/10/2020NICHD Research Education Programs (R25 Clinical Trial Not Allowed)
PAR-20-250 · Posted Date: 06/29/2020Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)
PA-20-222 · Posted Date: 05/29/2020NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
PA-20-207 · Posted Date: 05/07/2020Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R01 Clinical Trials Not Allowed)
PAR-20-165 · Posted Date: 04/13/2020Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R21 Clinical Trials Not Allowed)
PAR-20-168 · Posted Date: 04/13/2020Non-Viral Technologies for in vivo Delivery of Genome Editors (R43/R44 Clinical Trial Not Allowed)
PAR-20-098 · Posted Date: 02/06/2020Non-Viral Technologies for in vivo Delivery of Genome Editors (R41/R42 Clinical Trial Not Allowed)
PAR-20-109 · Posted Date: 02/06/2020Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)
PA-20-047 · Posted Date: 01/08/2020Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)
PA-20-025 · Posted Date: 01/07/2020Limited Competition: Competitive Revision Awards for the Clinical and Translational Science Award (CTSA) Program (U54 Clinical Trial Optional)
PAR-19-337 · Posted Date: 08/07/2019SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, R44) Clinical Trial Not Allowed
PAR-19-334 · Posted Date: 08/05/2019Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award, (U01 Clinical Trial Optional)
PAR-19-099 · Posted Date: 12/12/2018Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)
PA-19-034 · Posted Date: 10/24/2018Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)
PA-19-033 · Posted Date: 10/24/2018Innovation Corps (I-Corps™) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial Not Allowed)
PA-19-029 · Posted Date: 10/17/2018Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
PAR-18-953 · Posted Date: 10/04/2018Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed)
PAR-18-952 · Posted Date: 10/04/2018Clinical and Translational Science Award (U54 Clinical Trial Optional)
PAR-18-940 · Posted Date: 09/27/2018Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)
PA-18-837 · Posted Date: 06/20/2018Innovative Therapies and Tools for Screenable Disorders (R21 Clinical Trial Optional)
PAR-18-691 · Posted Date: 03/01/2018Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
PA-18-591 · Posted Date: 01/25/2018Clinical Trial Planning: Therapeutic/Indication Pairing Strategies (U34) (Clinical Trials Not Allowed)
PAR-18-462 · Posted Date: 11/30/2017Clinic Testing Therapeutic/Indication Pairing Strategies (U01 Clinical Trial Required)
PAR-18-332 · Posted Date: 10/20/2017Notices
Clarification on Prohibition on Expending NIH Grant Funds for Covered Telecommunications Equipment or Services
NOT-OD-21-041 · Posted Date: 12/11/2020Prohibition on Expending NIH Grant Funds for Covered Telecommunications Equipment or Services
NOT-OD-21-030 · Posted Date: 11/23/2020NIH Implementation of the Revised Federal-wide Research Terms and Conditions
NOT-OD-21-029 · Posted Date: 11/17/2020Extended Guidance for Applicants Preparing Applications During the COVID-19 Pandemic
NOT-OD-21-026 · Posted Date: 11/04/2020Supplemental Information to the NIH Policy for Data Management and Sharing: Allowable Costs for Data Management and Sharing
NOT-OD-21-015 · Posted Date: 10/29/2020Supplemental Information to the NIH Policy for Data Management and Sharing: Selecting a Repository for Data Resulting from NIH-Supported Research
NOT-OD-21-016 · Posted Date: 10/29/2020Final NIH Policy for Data Management and Sharing
NOT-OD-21-013 · Posted Date: 10/29/2020Supplemental Information to the NIH Policy for Data Management and Sharing: Elements of an NIH Data Management and Sharing Plan
NOT-OD-21-014 · Posted Date: 10/29/2020Notice of Special Interest (NOSI): Repurposing Existing Therapeutics to Address the 2019 Novel Coronavirus Disease (COVID-19)
NOT-TR-21-006 · Posted Date: 10/23/2020Notice Announcing Availability of Data Harmonization Tools for Social Determinants of Health (SDOH) via the PhenX Toolkit
NOT-MD-21-003 · Posted Date: 10/19/2020Policy for Charging Personal Protective Equipment to NIH Grants and Cooperative Agreements as Direct Costs
NOT-OD-20-164 · Posted Date: 09/11/2020Reminder: NIH Natural Disaster Policy Hurricane Laura
NOT-OD-20-172 · Posted Date: 09/11/2020Notice of Change to Key Dates for PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
NOT-TR-20-036 · Posted Date: 08/27/2020NCATS Announces Plans to Publish the ASPIRE 2020 Reduction-to-Practice Challenge Prize Competition
NOT-TR-20-035 · Posted Date: 08/26/2020Notice of Special Interest: Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP) - U.S. Entity (Admin Supp)
NOT-NS-20-024 · Posted Date: 05/05/2020Notice to Extend the Expiration Date for PAR-18-332 "Clinic Testing Therapeutic/Indication Pairing Strategies (U01 Clinical Trial Required)"
NOT-TR-20-026 · Posted Date: 04/27/2020Notice to Extend the Expiration Date for PAR-18-462 "Clinical Trial Planning: Therapeutic/Indication Pairing Strategies (U34) (Clinical Trial Not Allowed)"
NOT-TR-20-027 · Posted Date: 04/27/2020Notice of Special Interest: NCCIH Administrative Supplements to NCATS CTSA Programs for Scholars Pursuing Complementary Health Research Career Development
NOT-AT-20-010 · Posted Date: 04/13/2020Notice of Information: Change in NCATS Prior Approval Process for New CTSA Program Pilot Projects that Involve Human Subjects Research
NOT-TR-20-019 · Posted Date: 04/09/2020Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements for Tissue Chips Research on the 2019 Novel Coronavirus
NOT-TR-20-016 · Posted Date: 04/09/2020Notice of Special Interest: Clinical and Translational Science Award (CTSA) Program Administrative Supplements
NOT-TR-20-014 · Posted Date: 04/08/2020Notice of NCATS' Participation in PA-20-135 "Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)"
NOT-TR-20-013 · Posted Date: 04/08/2020Notice of Transition to New System for Issuing Certificates of Confidentiality for Non-NIH Funded Research
NOT-OD-20-075 · Posted Date: 02/28/2020Notice of Special Interest (NOSI): Availability of Administrative Supplements for the Rare Disease Clinical Research Network (RDCRN)
NOT-TR-20-006 · Posted Date: 02/27/2020Notice of Special Interest: Research through NCATS’ Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Awards (U01 and R21)
NOT-TR-20-007 · Posted Date: 02/18/2020Additional Guidance on the NIH Policy on the Use of a Single Institutional Review Board for Multi-Site Research
NOT-OD-20-058 · Posted Date: 01/22/2020Notice of Special Interest (NOSI): Next-Generation Approaches to Renal Replacement Therapy Including Vascular Access
NOT-DK-19-027 · Posted Date: 10/09/2019Extension of Certain Flexibilities for Prospective Basic Experimental Studies With Human Participants
NOT-OD-19-126 · Posted Date: 07/24/2019Notice of Change to NOT-TR-19-014: Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
NOT-TR-19-026 · Posted Date: 07/05/2019Notice of Special Interest: Administrative Supplements for Alternatives to the Use of Human Fetal Tissues for NIH Tissue Chip Programs
NOT-TR-19-019 · Posted Date: 04/18/2019Notification of Upcoming Change in Federal-wide Unique Entity Identifier Requirements
NOT-OD-19-098 · Posted Date: 04/11/2019Notice of Change to Key Dates for RFA-EB-18-003 "HEAL Initiative: Translational Development of Devices to Treat Pain (U18 Clinical Trial Not Allowed)"
NOT-NS-19-056 · Posted Date: 04/10/2019Notice of Change to Key Dates for RFA-NS-19-016 "HEAL Initiative: Translational Devices to Treat Pain (UG3/UH3 Clinical Trial Optional)"
NOT-NS-19-053 · Posted Date: 04/10/2019Notice of Change to Key Dates for RFA-NS-19-017 "HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)"
NOT-NS-19-054 · Posted Date: 04/10/2019Notice of Change to Key Dates for RFA-NS-19-018 "HEAL Initiative: Clinical Devices to Treat Pain (UH3 Clinical Trial Optional)"
NOT-NS-19-055 · Posted Date: 04/10/2019Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
NOT-TR-19-013 · Posted Date: 12/19/2018Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
NOT-TR-19-010 · Posted Date: 11/07/2018Notice of Change to PAR-18-953 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
NOT-TR-19-012 · Posted Date: 10/29/2018Notice of Change to PAR-18-952 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed)
NOT-TR-19-011 · Posted Date: 10/29/2018Reinstatement of NIH SBIR Direct-to-Phase II Authority and Associated Updates to NIH SBIR Omnibus Solicitations
NOT-OD-19-019 · Posted Date: 10/15/2018Additional Awards Eligible for PA-18-906 Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)
NOT-OD-18-226 · Posted Date: 09/04/2018Notice of Availability of Administrative Supplements for NIH Grants Focused on Down Syndrome to Address Specific Down Syndrome Research Objectives
NOT-OD-18-195 · Posted Date: 06/20/2018Notice of Availability of Administrative Supplements for the NCATS Clinical and Translational Science Awards (CTSA) Program
NOT-TR-18-022 · Posted Date: 04/20/2018Additional Awards Eligible for PA-18-592 Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers" (Admin Supp)
NOT-OD-18-153 · Posted Date: 03/15/2018NCATS Requests for Proposals
To find NCATS Requests for Proposals, visit FedBizOpps, type n01tr into the keyword field and click the search button.
NIH Clinical Trial Policy
Learn more about the NIH clinical trial requirements for grants and contracts and download slides that highlight policy changes.
NCATS Policy for Support of Clinical Trial Activities
This Notice informs the research community of the NCATS policy regarding support of clinical trial activities. The policy is designed to ensure compliance with the 21st Century Cures Act (Cures Act) as well as all pertinent statutes and existing NIH and NCATS policies; and considers the urgency of developing new treatments for rare diseases.
Collaborate with NCATS Scientists on the NIH HEAL Initiative
NCATS welcomes your NIH HEAL Initiative-related proposals to advance promising compounds and human cell-based models through preclinical development in collaboration with NCATS' intramural scientists.
NCATS’ Role in the NIH HEAL Initiative
As part of NIH HEAL Initiative, NCATS is applying breakthrough approaches of translational science to advance new treatments for opioid misuse and addiction and for pain. Learn more about NCATS' Role in the NIH HEAL Initiative.CTSA Program Funding News
Learn more about current funding opportunities for the Clinical and Translational Science Awards (CTSA) Program on the CTSA Program Funding Information page, including recent announcements and frequently asked questions.
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